VIOLIN: Vaccine Investigation and Online Information Network

Vaxjo: Vaccine Adjuvants

Currently, Vaxjo includes 448 vaccine adjuvants. The detailed curated data is shown below:

Index	Vaccine Adjuvant Name	No. of associated vaccines	VO ID
1	1P7	0	VO_0005516
2	1V270	1	VO_0005270
3	1Z105	0
4	2B182C	0	VO_0005271
5	2E151	0	VO_0005281
6	2F52	1	VO_0005303
7	2G023A	0	VO_0006097
8	2GO53	0	VO_0006098
9	3DSNA	0	VO_0005517
10	3M-052-AF	0	VO_0005474
11	3M-052-Alum	0	VO_0005387
12	3M-052-SE	0	VO_0005386
13	3pRNA	0	VO_0005518
14	7DW8-5	0	VO_0005515
15	A-910823	0	VO_0006103
16	AAHS	0	VO_0005715
17	AAV-IL-27	0	VO_0005729
18	Abisco-100 vaccine adjuvant	1	VO_0001334
19	ACM-CPG	0	VO_0006106
20	Ad-p53	0	VO_0005738
21	Ad-SLC	0	VO_0005739
22	Adamantylamide Dipeptide Vaccine Adjuvant	1	VO_0000559
23	Adjumer	1	VO_0000351
24	Adjuplex+GLA	0	VO_0005302
25	ADP-ribosylating adjuvant	0	VO_0005520
26	Advax	1	VO_0005207
27	Advax-CpG55.2	0	VO_0005324
28	AF03	1	VO_0001330
29	AH:CpG	0	VO_0005521
30	Aikejia	0	VO_0005522
31	Alarmin IL-33	0	VO_0005524
32	Albumin-heparin microparticles vaccine adjuvant	0	VO_0001335
33	ALF	0	VO_0005525
34	ALFQ	0	VO_0006096
35	Algal Glucan	0	VO_0001285
36	Algammulin	1	VO_0001286
37	Algel-IMDQ	0	VO_0005526
38	Alhydrogel	13	VO_0001241
39	Alhydroxiquim-II	1	VO_0005301
40	AlO(OH)-polymer nanoparticles	0	VO_0005527
41	AlT3	0	VO_0005300
42	AlT4	0	VO_0005299
43	Alum and IL-10	0	VO_0005528
44	Alum-TLR7	0
45	Alum/CpG-based formulation	0
46	aluminum hydroxide vaccine adjuvant	63	VO_0000127
47	aluminum phosphate vaccine adjuvant	49	VO_0000128
48	aluminum potassium sulfate adjuvant	6	VO_0001240
49	Aluminum vaccine adjuvant	14	VO_0000884
50	amorphous aluminum hydroxyphosphate sulfate adjuvant	2	VO_0001323
51	AmpB	0	VO_0005530
52	AP adjuvant	0	VO_0005532
53	APS	0	VO_0005533
54	Arlacel A	1	VO_0000191
55	AS-2 vaccine adjuvant	4	VO_0001264
56	AS01	0	VO_0005534
57	AS01B	0
58	AS02	4	VO_0001264
59	AS02A	0
60	AS03	2	VO_0001320
61	AS04	1	VO_0001265
62	AS15	0	VO_0005741
63	AS1517499	0	VO_0005742
64	ASPPR	0
65	Avridine®	1	VO_0001288
66	B7-2 vaccine adjuvant	1	VO_0001337
67	Babassu aqueous extract	0	VO_0005535
68	Bay R1005	1	VO_0001287
69	BECC438b	0	VO_0005298
70	BECC438s	0	VO_0005297
71	BECC470b	0	VO_0005296
72	BECC470s	0	VO_0005383
73	BI-Eng2	0	VO_0005507
74	BI-Eng2+Adjuplex	0	VO_0005508
75	BLP	0
76	Bordetella pertussis component Vaccine Adjuvant	3	VO_0000193
77	Bupivacaine vaccine adjuvant	0	VO_0001338
78	BVP22	0	VO_0005536
79	BX795	0
80	c-di-AMP	0	VO_0005731
81	C3 adjuvant	0	VO_0005537
82	C5a	0
83	C60(OH)22	0	VO_0005538
84	CA-CpG	0	VO_0005539
85	CAF-01	0	VO_0005483
86	CAF-09b	0	VO_0005473
87	CAF04	0	VO_0005540
88	CAF05	0	VO_0005541
89	CAF06	0	VO_0005542
90	CAF19	0	VO_0005543
91	CAF23	0	VO_0005544
92	CAF24a	0	VO_0005545
93	Calcium Phosphate Gel	0	VO_0001289
94	Calcium phosphate vaccine adjuvant	1	VO_0000131
95	Candida skin test reagent	0	VO_0005546
96	CaPNP (CaPtivant)(TM)	0	VO_0005295
97	carbon-silica nanocomposite	0	VO_0005547
98	CARP-1	0	VO_0005768
99	CARP-2	0	VO_0005775
100	caspase-1	0	VO_0005548
101	Cationic adjuvant formulations (CAFs)	0	VO_0005681
102	Cationic Liposomal Vaccine Adjuvant	2	VO_0001262
103	Cationic liposome-DNA complex JVRS-100	1	VO_0001339
104	CBP-12	0	VO_0005549
105	CCL19	0	VO_0005550
106	CCL21 and IL1β	0	VO_0005551
107	CCL3	0	VO_0005553
108	CCL34	0	VO_0005554
109	CCL5 adjuvant	0	VO_0005555
110	CD226	0	VO_0005556
111	CDG	0	VO_0005557
112	CGAMP	0	VO_0005558
113	Chitin	0	VO_0005559
114	Chitosan	0	VO_0005360
115	Cholera toxin	17	VO_0000143
116	Cholera toxin B subunit	6	VO_0001242
117	CITCO	0	VO_0005560
118	CL429	0	VO_0005573
119	CnB	0	VO_0005574
120	Corynebacterium-derived P40 Vaccine Adjuvant	1	VO_0000146
121	CoVaccine HT™	0	VO_0005575
122	Cowpea Mosaic Virus	0	VO_0006107
123	CPDI-01	0	VO_0005330
124	CPDI-02	0	VO_0006093
125	CPG 7909	0	VO_0005576
126	CpG andDcMNPs	0	VO_0005577
127	CpG DNA Vaccine Adjuvant	15	VO_0001237
128	CpG M362	0	VO_0005578
129	CpG oligodeoxynucleotide 1826	0	VO_0005579
130	CpG-MUC1-hydrogel	0	VO_0005580
131	CpG-ODN and Coa-ASC16	0	VO_0005581
132	CpG-ODN Shapes Alum Adjuvant	0
133	CRL1005	2	VO_0001318
134	Cry proteins	0	VO_0005582
135	CS3 adjuvant	0	VO_0005583
136	CTA	0	VO_0005584
137	CTA1-DD gene fusion protein	2	VO_0001290
138	CTA1-M2e-DD	0	VO_0005585
139	CTA2B	0	VO_0005586
140	CTB	0	VO_0005587
141	curcumin	0	VO_0005588
142	Curdlan	0	VO_0005767
143	CVC1302	0	VO_0005589
144	CXCL10	0
145	CXCL10-mucin-GPI	0	VO_0005590
146	CXCL11	0	VO_0005591
147	CXCL11-Fc	0	VO_0005592
148	CXCL9	0	VO_0005593
149	CyPA	0	VO_0005594
150	CYT387	0	VO_0005774
151	D-mannose	0	VO_0005595
152	D-Murapalmitine	0	VO_0001304
153	D-Murapalmitine	0	VO_0001305
154	DAI	0	VO_0005596
155	DDA Adjuvant	3	VO_0001261
156	DDO (Defective derived oligonucleotide)	1	VO_0005294
157	delta-inulin	0	VO_0005723
158	DHEA vaccine adjuvant	1	VO_0001340
159	dibutyl phthalate	0	VO_0005369
160	DL-PGL (Polyester poly (DL-lactide-co-glycolide)) vaccine adjuvant	1	VO_0001341
161	DLinDMA	0	VO_0005597
162	dmLT (double mutant of heat-labile E.coli)	0	VO_0005329
163	DOC/Alum Complex	1	VO_0001291
164	DOTAP and DP7-C liposomes	0	VO_0005598
165	E. coli heat-labile toxin, LT	3	VO_0001322
166	EGCG	0	VO_0005599
167	Em	0	VO_0005293
168	EmT4	0	VO_0005292
169	EP67	0	VO_0005765
170	epigallocatechin-3-gallate	0	VO_0005599
171	Etx B subunit Adjuvant	2	VO_0001272
172	Evax-B	0	VO_0005510
173	Evax-S	0	VO_0005511
174	FimH	0	VO_0005600
175	FLAB-PSPA	0	VO_0005601
176	Flagellin	1	VO_0001331
177	FLIC	0	VO_0005602
178	Flt-3 ligand	0	VO_0005603
179	Fos47	0	VO_0005291
180	Freund's Complete Adjuvant	45	VO_0000139
181	Freund's Incomplete Adjuvant	46	VO_0000142
182	Fuc-Sc	0	VO_0005604
183	G2	0	VO_0005605
184	G3	0	VO_0005606
185	Gamma Inulin	1	VO_0001292
186	GC@ICG nanoparticle	0	VO_0005607
187	GDQ	0	VO_0005754
188	Gel-gffy	0	VO_0005608
189	Gerbu Adjuvant	1	VO_0001293
190	GITRL	0	VO_0005609
191	GLA-3M-052-LS	0	VO_0005385
192	GLA-AF	0	VO_0005424
193	GLA-Alum	0	VO_0006099
194	GLA-LSQ	0	VO_0005421
195	GLA-SE	0	VO_0005420
196	glycated chitosan	0	VO_0005610
197	glycerol	0	VO_0005370
198	GM-CSF	27	VO_0001294
199	GM3	0	VO_0005611
200	GMDP	1	VO_0001295
201	gp63	0	VO_0005612
202	GPI-0100	0	VO_0005763
203	GPI-CCL28	0	VO_0005552
204	Granules of mast cells	0	VO_0005613
205	Granulysin	0	VO_0005614
206	Graphene oxide	0	VO_0005615
207	HAV-aCNP	0	VO_0005616
208	HBcAg	0	VO_0005617
209	HBHA	0	VO_0005618
210	HBsAg	0	VO_0005779
211	hexosomes	0	VO_0005619
212	HIV-1 protease	0	VO_0005620
213	HMBA	0	VO_0005621
214	HMGB1	0	VO_0005622
215	HP-?-CD	0
216	Hsp65	0	VO_0005761
217	HVJ-Envelope	0	VO_0005762
218	IBL027	0	VO_0005623
219	IFN-α	0	VO_0005624
220	IFNβ	0	VO_0005625
221	IL-12 Vaccine Adjuvant	14	VO_0001147
222	IL-12-MOP	0	VO_0005509
223	IL-15	1	VO_0001342
224	IL-15 plasmid vaccine adjuvant	0	VO_0000384
225	IL-18	0	VO_0005627
226	IL-1R1	0	VO_0005628
227	IL-21	0	VO_0005629
228	IL-27	0	VO_0005630
229	IL-33	0	VO_0005631
230	IL-36	0	VO_0005632
231	IL-4	0	VO_0005633
232	IL-7	1	VO_0001299
233	IL-7-Fc	0	VO_0005634
234	IL15	1	VO_0005270
235	Imiquimod	1	VO_0001328
236	Immunoliposomes Containing Antibodies to Costimulatory Molecules	1	VO_0001343
237	IMP321	0	VO_0005635
238	INI-2002	0	VO_0005290
239	INI-2004	0	VO_0005289
240	INI-4001	0	VO_0005288
241	Injectable Excipients	0	VO_0005679
242	Interleukin-1β	1	VO_0001297
243	Interleukin-2	1	VO_0001298
244	Interleukin-7	1	VO_0001299
245	IPMPs	0	VO_0005637
246	iron oxide nanoparticles	0	VO_0005638
247	IRX-2	0	VO_0005639
248	ISCOM(s)™	2	VO_0000757
249	ISCOMATRIX®	1	VO_0001333
250	ISG15	0	VO_0005640
251	α-galactosylceramide	0	VO_0005724
252	α-GalCer and MPL	0	VO_0005725
253	K3-SPG	0	VO_0005641
254	Killed Corynebacterium parvum Vaccine Adjuvant	2	VO_0001259
255	KML-B	0	VO_0005642
256	Kynurenine	0	VO_0005643
257	L-NAME	0	VO_0005644
258	L-siRNA	0	VO_0005645
259	L. polysaccharide	0	VO_0005746
260	LAB EPS	0	VO_0005726
261	LAG-3	0
262	LCP	0	VO_0005736
263	Levamisole	0	VO_0005760
264	LIGHT	0	VO_0005646
265	Lipopolysaccharide Vaccine Adjuvant	1	VO_0000181
266	Liposomes	2	VO_0000366
267	Listeriolysin O	0	VO_0005647
268	LiT4	0	VO_0005287
269	LMQ	0	VO_0006092
270	Loxoribine	1	VO_0001300
271	LP-GMP	0	VO_0005648
272	LQ	0	VO_0005390
273	LT(R192G)	6	VO_0001321
274	LT-IIb	0	VO_0005649
275	LTA1	0	VO_0005355
276	LTK63 Vaccine Mutant Adjuvant	2	VO_0001251
277	LTR192G Vaccine Adjuvant	6	VO_0001321
278	LTR72 vaccine adjuvant	1	VO_0001344
279	Man-TLR7	0	VO_0005650
280	Mannadjuvant	0	VO_0005286
281	MAS-1	0	VO_0005471
282	Mast Cell Activator Small Muscles	0	VO_0005381
283	Mastoparan 7	0	VO_0005380
284	Matrix-M	2	VO_0005206
285	Matrix-S	1	VO_0001324
286	MCP-3	0	VO_0005651
287	MDA5	0	VO_0005652
288	MDP-1	0	VO_0005653
289	ME-F-1051	0	VO_0005512
290	ME-F-1122	0	VO_0005513
291	melatonin	0	VO_0005538
292	mesoporous silica nanoparticle	0	VO_0005654
293	MF59	5	VO_0001301
294	MicroCyrstalline Tyrosine® (MCT)	0	VO_0005419
295	MIP-1alpha	0	VO_0005759
296	MIP-2	0	VO_0005655
297	MiT4	0	VO_0005285
298	MMG-1	0	VO_0005656
299	monomeric annexin A2	0	VO_0005531
300	Montanide 103	0	VO_0000192
301	Montanide IMS 1313	0	VO_0000192
302	Montanide Incomplete Seppic Adjuvant	1	VO_0001269
303	Montanide ISA 206	0	VO_0005362
304	Montanide ISA 51	2	VO_0001270
305	Montanide ISA 720	6	VO_0001268
306	Montanide ISA 720 Adjuvant	6	VO_0001268
307	MPL	9	VO_0001250
308	MPL + TDM	0	VO_0005367
309	MPL-SE vaccine adjuvant	2	VO_0001345
310	MPL™ Adjuvant	9	VO_0001250
311	MSP-102	0	VO_0005657
312	MTP-PE Liposomes	2	VO_0001302
313	MUC1 based adjuvant-protein-antigen	0	VO_0005658
314	Murabutide	0	VO_0005752
315	Murametide	0	VO_0001303
316	Muramyl Dipeptide Adjuvant	1	VO_0000187
317	Myd88	0	VO_0005660
318	MyD88/CD40	0	VO_0005659
319	NADA	0	VO_0005755
320	NAGO	1	VO_0001306
321	Naltrexone	0	VO_0005661
322	NanoAlum	0	VO_0005475
323	nanoemulsion vaccine adjuvant	3	VO_0001319
324	Nanostructured Lipid Carrier (NLC)	0	VO_0005476
325	NanoVax/NE01	0	VO_0005284
326	Nexavant	0	VO_0006108
327	Non-Ionic Surfactant Vesicles	1	VO_0001307
328	non-toxic mutant E112K of Cholera Toxin mCT-E112K	1	VO_0001347
329	NP DNA adjuvant	0	VO_0005662
330	NP-3pRNA-CpG	0	VO_0005663
331	NP-R@M-M	0	VO_0005664
332	NS-TLR	0	VO_0005749
333	OK-432	0	VO_0005665
334	OMPC-TLR2	0	VO_0005666
335	Ophiopogonin D	0	VO_0005667
336	OVA-csNLCs	0	VO_0005668
337	OVA-LNPs	0	VO_0005669
338	P2Et	0	VO_0005670
339	PAA:nanoalum	0	VO_0005671
340	Pam3Cys	0	VO_0005371
341	PAMK	0	VO_0005672
342	PAPE	0	VO_0005673
343	pcIFN-gamma	0	VO_0005727
344	PCL and chitosan NPs	0
345	PEI-PPAS	0	VO_0005674
346	PET Lipid A	0	VO_0005675
347	PHAD	0	VO_0005757
348	PhotothermalPhage	0	VO_0005676
349	PI-RI	0	VO_0005677
350	PI-sRI	0	VO_0005678
351	PIKA	0	VO_0005379
352	Pinaceae-derived nanoemulsions	0	VO_0005679
353	PLA-b-P(NAS-co-NVP)	0	VO_0005680
354	Platycodin D	0	VO_0005682
355	PLGA	0	VO_0005684
356	PMMA	1	VO_0001308
357	PNPS-0.3	0	VO_0005685
358	Poly(I:C)	1	VO_0001332
359	Poly-ϵ-caprolactone and chitosan nanoparticles	0	VO_0005686
360	Polyethyleneimine	0	VO_0005687
361	Polygen Vaccine Adjuvant	1	VO_0001273
362	PolyIC:LC	0	VO_0005688
363	Polyinosinic-polycytidylic acid	0	VO_0005661
364	polysorbitol-co-PEI polymer	0	VO_0005689
365	porous silicon microparticle	0	VO_0005690
366	Precision Vaccines Program (PVP)-037	0	VO_0005382
367	Precision Vaccines Program (PVP)-057	0	VO_0006105
368	Pro-LNG-S	0	VO_0005472
369	Propionibacterium acnes(P. acnes)	0	VO_0005691
370	Protein Cochleates	1	VO_0001309
371	PRR agonists	0	VO_0005669
372	pSPreS2	0	VO_0005692
373	QS-17 and18	0	VO_0005693
374	QS-21	1	VO_0001310
375	Quil-A vaccine adjuvant	6	VO_0001263
376	RALDH2	0	VO_0005694
377	RC529 vaccine adjuvant	1	VO_0001239
378	rcIL-15	0	VO_0005728
379	Recombinant hIFN-gamma/Interferon-g	1	VO_0001296
380	Rehydragel HPA	1	VO_0001311
381	Rehydragel LV	1	VO_0001312
382	Resiquimod	0	VO_0001329
383	retinoic acid and IL-15	0	VO_0005695
384	rhIL-7 adjuvant	0	VO_0005730
385	Ribi Vaccine Adjuvant	11	VO_0001238
386	RNadjuvant	0	VO_0005697
387	rNDV-mOX40L	0	VO_0005698
388	Rotavirus VP6	0	VO_0005699
389	rOv-ASP-1	0	VO_0005327
390	Rv3628	0	VO_0005700
391	S-540956	0	VO_0006104
392	SAF-1	1	VO_0001349
393	SAG1 and TLR-5 ligand	0	VO_0005701
394	saponin and MPLA nanoparticles	0	VO_0006095
395	Saponin Monophosphoryl Lipid-A Nanoparticles	0	VO_0006095
396	Saponin Vaccine Adjuvant	4	VO_0001267
397	SBAS2	0	VO_0005750
398	Sclavo peptide	0	VO_0001313
399	Sendai Proteoliposomes, Sendai-containing Lipid Matrices	0	VO_0001350
400	Shrimp anti-lipopolysaccharide factor	0	VO_0005702
401	SLA-AF	0	VO_0005482
402	SLA-Alum	0	VO_0006100
403	SLA-LSQ	0	VO_0005422
404	SLA-SE	0	VO_0005423
405	solid nanoemulsion	0	VO_0005703
406	solid-in-oil-in-water emulsion	0	VO_0005704
407	sPD-1	0	VO_0005705
408	Specol	1	VO_0001314
409	spontaneous nanoliposome antigen particleization	0	VO_0005707
410	SPT (Antigen Formulation)	1	VO_0001315
411	SQ	0	VO_0005389
412	Squalene-based Adjuvants	1	VO_0000190
413	Stable Emulsion (SE) vaccine adjuvant	0	VO_0006101
414	Stearyl Tyrosine	1	VO_0001316
415	sticholysin II	0	VO_0005708
416	SWE	0	VO_0005388
417	t-NanoCpG	0	VO_0005710
418	T-vant	0	VO_0005375
419	T7-alum	0	VO_0005711
420	Taishan Robinia Pseudoacacia polysaccharides	0	VO_0005712
421	TDM	0	VO_0005713
422	TF-Al	0	VO_0005714
423	Theramide®	1	VO_0001317
424	Threonyl muramyl dipeptide (TMDP)	1	VO_0001351
425	TiterMax Gold Adjuvant	3	VO_0001260
426	TLR-7 andTLR-8 Agonist	0	VO_0005674
427	TLR3	1	VO_0001332
428	TLR4 agonist lipopolysaccharides	1	VO_0005270
429	TLR5	1	VO_0005270
430	TLR7-8 RNA ligands	0	VO_0005718
431	TLRa	0	VO_0005656
432	TQL-1055	0	VO_0005283
433	TRAC478	0	VO_0005384
434	trichosanthin	0	VO_0005719
435	TRIF	0	VO_0005720
436	Tumour-derived exosomes (TEXs)	0	VO_0005721
437	Ty Particles vaccine adjuvant	1	VO_0001352
438	U-Omp19 and alum	0	VO_0005722
439	UM-1098	0	VO_0005282
440	UM-3003	0	VO_0005354
441	UM-3004	0	VO_0005353
442	UM-3005	0	VO_0005337
443	V155M	0	VO_0005735
444	VISA	0	VO_0005723
445	VLP@Silica	0	VO_0005732
446	VSA-1	0	VO_0005326
447	VSA-2	0	VO_0005325
448	VSA-3 Adjuvant	2	VO_0001266
Total		419 (unique ones)

Vaccines with adjuvants by vaccine targeted pathogens or diseases

Pathogen or disease	No. of pathogen species	DNA vaccine	Toxoid vaccine	Subunit vaccine	Subunit vaccine + Inactivated or "killed" vaccine	Conjugate vaccine	Inactivated or "killed" vaccine	Recombinant vector vaccine	Live, attenuated vaccine	Fusion protein with adjuvant	Other	trivalent human seasonal influenza vaccine (TIV)	protein-nanoparticle vaccine	Prime-boost vaccine with DNA vaccine priming	Total
G- bacterium	22/51	2	6	97	11	7	2	6	0	0	0	0	0	0	131
G+ bacterium	11/17	2	26	39	17	6	4	1	0	1	0	0	0	0	96
parasite	15/25	6	0	53	0	0	1	4	1	0	0	0	1	2	68
Allergy	1/1	0	0	1	0	0	0	0	0	0	0	0	0	0	1
Cancer	1/1	7	0	12	0	1	0	8	1	0	4	0	0	0	33
Atherosclerosis	1/1	0	0	2	0	0	0	0	0	0	0	0	0	0	2
virus	28/115	2	0	44	11	0	23	1	3	0	0	1	0	0	85
fungus	1/1	0	0	3	0	0	0	0	0	0	0	0	0	0	3
Total	80/212	19	32	251	39	14	30	20	5	1	4	1	1	2	419

Click here for the list of vaccines that use two or more adjuvants.