VIOLIN: Vaccine Investigation and Online Information Network

Vaxjo: Vaccine Adjuvants

Currently, Vaxjo includes 396 vaccine adjuvants. The detailed curated data is shown below:

Index	Vaccine Adjuvant Name	No. of associated vaccines	VO ID
1	1P7	0	VO_0005516
2	1V270	1	VO_0005270
3	2B182C	0	VO_0005271
4	2E151	0	VO_0005281
5	2F52	1	VO_0005303
6	2G023A	0	VO_0006097
7	2GO53	0	VO_0006098
8	3DSNA	0	VO_0005517
9	3M-052-AF	0	VO_0005474
10	3M-052-Alum	0	VO_0005387
11	3M-052-SE	0	VO_0005386
12	3pRNA	0	VO_0005518
13	7DW8-5	0	VO_0005515
14	A-910823	0	VO_0006103
15	AAHS	0	VO_0005715
16	AAV-IL-27	0	VO_0005729
17	Abisco-100 vaccine adjuvant	1	VO_0001334
18	ACM-CPG	0	VO_0006106
19	Ad-p53	0	VO_0005738
20	Ad-SLC	0	VO_0005739
21	Adamantylamide Dipeptide Vaccine Adjuvant	1	VO_0000559
22	Adjumer	1	VO_0000351
23	Adjuplex+GLA	0	VO_0005302
24	ADP-ribosylating adjuvant	0	VO_0005520
25	Advax	1	VO_0005207
26	Advax-CpG55.2	0	VO_0005324
27	AF03	1	VO_0001330
28	AH:CpG	0	VO_0005521
29	Aikejia	0	VO_0005522
30	Alarmin IL-33	0	VO_0005524
31	Albumin-heparin microparticles vaccine adjuvant	0	VO_0001335
32	ALF	0	VO_0005525
33	ALFQ	0	VO_0006096
34	Algal Glucan	0	VO_0001285
35	Algammulin	1	VO_0001286
36	Algel-IMDQ	0	VO_0005526
37	Alhydrogel	13	VO_0001241
38	Alhydroxiquim-II	1	VO_0005301
39	AlO(OH)-polymer nanoparticles	0	VO_0005527
40	AlT3	0	VO_0005300
41	AlT4	0	VO_0005299
42	Alum and IL-10	0	VO_0005528
43	Alum-TLR7	0
44	aluminum hydroxide vaccine adjuvant	63	VO_0000127
45	aluminum phosphate vaccine adjuvant	49	VO_0000128
46	aluminum potassium sulfate adjuvant	6	VO_0001240
47	Aluminum vaccine adjuvant	14	VO_0000884
48	amorphous aluminum hydroxyphosphate sulfate adjuvant	2	VO_0001323
49	AmpB	0	VO_0005530
50	AP adjuvant	0	VO_0005532
51	APS	0	VO_0005533
52	Arlacel A	1	VO_0000191
53	AS-2 vaccine adjuvant	4	VO_0001264
54	AS01	0	VO_0005534
55	AS02	4	VO_0001264
56	AS03	2	VO_0001320
57	AS04	1	VO_0001265
58	AS15	0	VO_0005741
59	Avridine®	1	VO_0001288
60	B7-2 vaccine adjuvant	1	VO_0001337
61	Babassu aqueous extract	0	VO_0005535
62	Bay R1005	1	VO_0001287
63	BECC438b	0	VO_0005298
64	BECC438s	0	VO_0005297
65	BECC470b	0	VO_0005296
66	BECC470s	0	VO_0005383
67	BI-Eng2	0	VO_0005507
68	BI-Eng2+Adjuplex	0	VO_0005508
69	Bordetella pertussis component Vaccine Adjuvant	3	VO_0000193
70	Bupivacaine vaccine adjuvant	0	VO_0001338
71	c-di-AMP	0	VO_0005731
72	C3 adjuvant	0	VO_0005537
73	C60(OH)22	0	VO_0005538
74	CA-CpG	0	VO_0005539
75	CAF-01	0	VO_0005483
76	CAF-09	0	VO_0005473
77	CAF04	0	VO_0005540
78	CAF05	0	VO_0005541
79	CAF06	0	VO_0005542
80	CAF23	0	VO_0005544
81	CAF24a	0	VO_0005545
82	Calcium Phosphate Gel	0	VO_0001289
83	Calcium phosphate vaccine adjuvant	1	VO_0000131
84	Candida skin test reagent	0	VO_0005546
85	CaPNP (CaPtivant)(TM)	0	VO_0005295
86	CARP-2	0
87	caspase-1	0	VO_0005548
88	Cationic adjuvant formulations (CAFs)	0	VO_0005681
89	Cationic Liposomal Vaccine Adjuvant	2	VO_0001262
90	Cationic liposome-DNA complex JVRS-100	1	VO_0001339
91	CBP-12	0	VO_0005549
92	CCL19	0	VO_0005550
93	CCL21 and IL1β	0	VO_0005551
94	CCL5 adjuvant	0	VO_0005555
95	CD226	0	VO_0005556
96	CDG	0	VO_0005557
97	CGAMP	0	VO_0005558
98	Chitosan	0	VO_0005360
99	Cholera toxin	17	VO_0000143
100	Cholera toxin B subunit	6	VO_0001242
101	CITCO	0	VO_0005560
102	CL429	0	VO_0005573
103	CnB	0	VO_0005574
104	Corynebacterium-derived P40 Vaccine Adjuvant	1	VO_0000146
105	CoVaccine HT™	0	VO_0005575
106	Cowpea Mosaic Virus	0	VO_0006107
107	CPDI-01	0	VO_0005330
108	CPDI-02	0	VO_0006093
109	CPG 7909	0	VO_0005576
110	CpG andDcMNPs	0	VO_0005577
111	CpG DNA Vaccine Adjuvant	15	VO_0001237
112	CpG M362	0	VO_0005578
113	CpG oligodeoxynucleotide 1826	0	VO_0005579
114	CpG-ODN and Coa-ASC16	0	VO_0005581
115	CpG-ODN Shapes Alum Adjuvant	0
116	CRL1005	2	VO_0001318
117	Cry proteins	0	VO_0005582
118	CS3 adjuvant	0	VO_0005583
119	CTA	0	VO_0005584
120	CTA1-DD gene fusion protein	2	VO_0001290
121	CTA1-M2e-DD	0
122	CTA2B	0	VO_0005586
123	CTB	0	VO_0005587
124	curcumin	0	VO_0005588
125	CVC1302	0	VO_0005589
126	CXC11	0
127	CXCL10	0
128	CXCL11-Fc	0	VO_0005592
129	CXCL9	0	VO_0005593
130	CyPA	0	VO_0005594
131	D-mannose	0	VO_0005595
132	D-Murapalmitine	0	VO_0001305
133	DAI	0	VO_0005596
134	DDA Adjuvant	3	VO_0001261
135	DDO (Defective derived oligonucleotide)	1	VO_0005294
136	delta-inulin	0	VO_0005723
137	DHEA vaccine adjuvant	1	VO_0001340
138	DL-PGL (Polyester poly (DL-lactide-co-glycolide)) vaccine adjuvant	1	VO_0001341
139	DLinDMA	0	VO_0005597
140	dmLT (double mutant of heat-labile E.coli)	0	VO_0005329
141	DOC/Alum Complex	1	VO_0001291
142	DOTAP and DP7-C liposomes	0	VO_0005598
143	E. coli heat-labile toxin, LT	3	VO_0001322
144	EGCG	0	VO_0005749
145	Em	0	VO_0005293
146	EmT4	0	VO_0005292
147	epigallocatechin-3-gallate	0	VO_0005599
148	Etx B subunit Adjuvant	2	VO_0001272
149	Evax-B	0	VO_0005510
150	Evax-S	0	VO_0005511
151	FLAB-PSPA	0	VO_0005601
152	Flagellin	1	VO_0001331
153	FLIC	0	VO_0005602
154	Flt-3 ligand	0	VO_0005603
155	Fos47	0	VO_0005291
156	Freund's Complete Adjuvant	45	VO_0000139
157	Freund's Incomplete Adjuvant	46	VO_0000142
158	Fuc-Sc	0	VO_0005604
159	G2	0	VO_0005605
160	G3	0	VO_0005606
161	Gamma Inulin	1	VO_0001292
162	GC@ICG nanoparticle	0	VO_0005607
163	GDQ	0
164	Gel-gffy	0	VO_0005608
165	Gerbu Adjuvant	1	VO_0001293
166	GITRL	0	VO_0005609
167	GLA-3M-052-LS	0	VO_0005385
168	GLA-AF	0	VO_0005424
169	GLA-Alum	0	VO_0006099
170	GLA-LSQ	0	VO_0005421
171	GLA-SE	0	VO_0005420
172	glycated chitosan	0	VO_0005610
173	GM-CSF	27	VO_0001294
174	GM3	0	VO_0005611
175	GMDP	1	VO_0001295
176	gp63	0	VO_0005612
177	GPI-CCL28	0	VO_0005552
178	Granules of mast cells	0	VO_0005613
179	Granulysin	0	VO_0005614
180	Graphene oxide	0	VO_0005615
181	HBcAg	0	VO_0005617
182	HBHA	0	VO_0005618
183	HBsAg	0	VO_0005779
184	hexosomes	0	VO_0005619
185	HIV-1 protease	0	VO_0005620
186	HMBA	0	VO_0005621
187	HMGB1	0	VO_0005622
188	Hsp65	0
189	IBL027	0	VO_0005623
190	IFN-α	0	VO_0005624
191	IFNβ	0	VO_0005625
192	IL-12 Vaccine Adjuvant	14	VO_0001147
193	IL-12-MOP	0	VO_0005509
194	IL-15 vaccine adjuvant	1	VO_0001342
195	IL-1R1	0	VO_0005628
196	IL-21	0	VO_0005629
197	IL-27	0	VO_0005630
198	IL-36	0	VO_0005632
199	IL-7-Fc	0	VO_0005634
200	IL15	1	VO_0005270
201	Imiquimod	1	VO_0001328
202	Immunoliposomes Containing Antibodies to Costimulatory Molecules	1	VO_0001343
203	IMP321	0	VO_0005635
204	INI-2002	0	VO_0005290
205	INI-2004	0	VO_0005289
206	INI-4001	0	VO_0005288
207	Injectable Excipients	0	VO_0005679
208	Interleukin-1β	1	VO_0001297
209	Interleukin-2	1	VO_0001298
210	Interleukin-7	1	VO_0001299
211	IPMPs	0	VO_0005637
212	iron oxide nanoparticles	0	VO_0005638
213	IRX-2	0	VO_0005639
214	ISCOM(s)™	2	VO_0000757
215	ISCOMATRIX®	1	VO_0001333
216	ISG15	0	VO_0005640
217	α-galactosylceramide	0	VO_0005724
218	α-GalCer and MPL	0	VO_0005725
219	K3-SPG	0	VO_0005641
220	Killed Corynebacterium parvum Vaccine Adjuvant	2	VO_0001259
221	KML-B	0	VO_0005642
222	Kynurenine	0	VO_0005643
223	L-NAME	0	VO_0005644
224	L-siRNA	0	VO_0005645
225	L. polysaccharide	0	VO_0005746
226	LAG-3	0
227	LCP	0	VO_0005736
228	LIGHT	0	VO_0005646
229	Lipopolysaccharide Vaccine Adjuvant	1	VO_0000181
230	Liposomes	2	VO_0000366
231	Listeriolysin O	0	VO_0005647
232	LiT4	0	VO_0005287
233	LMQ	0	VO_0006092
234	Loxoribine	1	VO_0001300
235	LP-GMP	0	VO_0005648
236	LQ	0	VO_0005390
237	LT(R192G)	0	VO_0005528
238	LT-IIb	0	VO_0005649
239	LTA1	0	VO_0005355
240	LTK63 Vaccine Mutant Adjuvant	2	VO_0001251
241	LTR192G Vaccine Adjuvant	6	VO_0001321
242	LTR72 vaccine adjuvant	1	VO_0001344
243	Man-TLR7	0	VO_0005650
244	Mannadjuvant	0	VO_0005286
245	MAS-1	0	VO_0005471
246	Mast Cell Activator Small Muscles	0	VO_0005381
247	Mastoparan 7	0	VO_0005380
248	Matrix-S	1	VO_0001324
249	MCP-3	0	VO_0005651
250	MDA5	0	VO_0005652
251	MDP-1	0	VO_0005653
252	Melatonin	0	VO_0005538
253	mesoporous silica nanoparticle	0	VO_0005654
254	MF59	5	VO_0001301
255	MicroCyrstalline Tyrosine® (MCT)	0	VO_0005419
256	MiT4	0	VO_0005285
257	MMG-1	0	VO_0005656
258	monomeric annexin A2	1	VO_0005270
259	Montanide Incomplete Seppic Adjuvant	1	VO_0001269
260	Montanide ISA 51	2	VO_0001270
261	Montanide ISA 720 Adjuvant	6	VO_0001268
262	MPL	9	VO_0001250
263	MPL + TDM	0
264	MPL-SE vaccine adjuvant	2	VO_0001345
265	MPL™ Adjuvant	9	VO_0001250
266	MSP-102	0	VO_0005657
267	MTP-PE Liposomes	2	VO_0001302
268	Murametide	0	VO_0001303
269	Muramyl Dipeptide Adjuvant	1	VO_0000187
270	Murapalmitine	0	VO_0001304
271	Myd88	0	VO_0005660
272	MyD88/CD40	0	VO_0005659
273	NAGO	1	VO_0001306
274	Naltrexone	0	VO_0005661
275	NanoAlum	0	VO_0005475
276	nanoemulsion vaccine adjuvant	3	VO_0001319
277	Nanostructured Lipid Carrier (NLC)	0	VO_0005476
278	NanoVax/NE01	0	VO_0005284
279	Nexavant	0	VO_0006108
280	Non-Ionic Surfactant Vesicles	1	VO_0001307
281	non-toxic mutant E112K of Cholera Toxin mCT-E112K	1	VO_0001347
282	NP DNA adjuvant	0	VO_0005662
283	NP-3pRNA-CpG	0
284	NP-R@M-M	0	VO_0005664
285	NS-TLR	0	VO_0005749
286	OK-432	0	VO_0005665
287	Ophiopogonin D	0	VO_0005667
288	OVA-csNLCs	0	VO_0005668
289	P2Et	0	VO_0005670
290	PAA:nanoalum	0	VO_0005671
291	PAMK	0	VO_0005672
292	PAPE	0	VO_0005673
293	pcIFN-gamma	0	VO_0005727
294	PCL and chitosan NPs	0
295	PEI-PPAS	0	VO_0005674
296	PET Lipid A	0	VO_0005675
297	PhotothermalPhage	0	VO_0005676
298	PI-RI	0	VO_0005677
299	PI-sRI	0	VO_0005678
300	PIKA	0	VO_0005379
301	Pinaceae-derived nanoemulsions	0	VO_0005679
302	PLA-b-P(NAS-co-NVP)	0	VO_0005680
303	Platycodin D	0	VO_0005682
304	PLGA	0	VO_0005684
305	PMMA	1	VO_0001308
306	Poly(I:C)	1	VO_0001332
307	Poly-ϵ-caprolactone and chitosan nanoparticles	0	VO_0005686
308	Polyethyleneimine	0	VO_0005687
309	Polygen Vaccine Adjuvant	1	VO_0001273
310	PolyIC:LC	0	VO_0005688
311	Polyinosinic-polycytidylic acid	0	VO_0005661
312	polysorbitol-co-PEI polymer	0	VO_0005689
313	porous silicon microparticle	0	VO_0005690
314	Precision Vaccines Program (PVP)-037	0	VO_0005382
315	Precision Vaccines Program (PVP)-057	0	VO_0006105
316	Pro-LNG-S	0	VO_0005472
317	Propionibacterium acnes(P. acnes)	0	VO_0005691
318	Protein Cochleates	1	VO_0001309
319	PRR agonists	0	VO_0005669
320	pSPreS2	0	VO_0005692
321	QS-17 and18	0	VO_0005693
322	QS-21	1	VO_0001310
323	Quil-A vaccine adjuvant	6	VO_0001263
324	RALDH2	0	VO_0005694
325	RC529 vaccine adjuvant	1	VO_0001239
326	rcIL-15	0	VO_0005728
327	Recombinant hIFN-gamma/Interferon-g	1	VO_0001296
328	Rehydragel HPA	1	VO_0001311
329	Rehydragel LV	1	VO_0001312
330	Resiquimod	0	VO_0001329
331	retinoic acid and IL-15	0	VO_0005695
332	rhIL-7 adjuvant	0	VO_0005730
333	Ribi Vaccine Adjuvant	11	VO_0001238
334	RNadjuvant	0	VO_0005697
335	rNDV-mOX40L	0	VO_0005698
336	Rotavirus VP6	0	VO_0005699
337	rOv-ASP-1	0	VO_0005327
338	Rv3628	0	VO_0005700
339	S-540956	0	VO_0006104
340	SAF-1	1	VO_0001349
341	SAG1 and TLR-5 ligand	0	VO_0005701
342	saponin and MPLA nanoparticles	0	VO_0006095
343	Saponin Monophosphoryl Lipid-A Nanoparticles	0	VO_0006095
344	Saponin Vaccine Adjuvant	4	VO_0001267
345	SBAS2	0	VO_0005750
346	Sclavo peptide	0	VO_0001313
347	Sendai Proteoliposomes, Sendai-containing Lipid Matrices	0	VO_0001350
348	Shrimp anti-lipopolysaccharide factor	0	VO_0005702
349	SLA-AF	0	VO_0005482
350	SLA-Alum	0	VO_0006100
351	SLA-LSQ	0	VO_0005422
352	SLA-SE	0	VO_0005423
353	solid nanoemulsion	0	VO_0005703
354	solid-in-oil-in-water emulsion	0	VO_0005704
355	sPD-1	0	VO_0005705
356	Specol	1	VO_0001314
357	spontaneous nanoliposome antigen particleization	0	VO_0005707
358	SPT (Antigen Formulation)	1	VO_0001315
359	SQ	0	VO_0005389
360	Squalene-based Adjuvants	1	VO_0000190
361	Stable Emulsion (SE) vaccine adjuvant	0	VO_0006101
362	Stearyl Tyrosine	1	VO_0001316
363	sticholysin \|\|	0	VO_0005708
364	SWE	0	VO_0005388
365	t-NanoCpG	0	VO_0005710
366	T-vant	0	VO_0005375
367	T7-alum	0	VO_0005711
368	Taishan Robinia Pseudoacacia polysaccharides	0	VO_0005712
369	TDM	0	VO_0005713
370	TF-Al	0	VO_0005714
371	Theramide®	1	VO_0001317
372	Threonyl muramyl dipeptide (TMDP)	1	VO_0001351
373	TiterMax Gold Adjuvant	3	VO_0001260
374	TLR-7 andTLR-8 Agonist	0	VO_0005674
375	TLR3	1	VO_0001332
376	TLR4 agonist lipopolysaccharides	1	VO_0005270
377	TLR5	1	VO_0005270
378	TLR7-8 RNA ligands	0	VO_0005718
379	TLRa	0	VO_0005656
380	TQL-1055	0	VO_0005283
381	TRAC478	0	VO_0005384
382	trichosanthin	0	VO_0005719
383	TRIF	0	VO_0005720
384	Tumour-derived exosomes (TEXs)	0	VO_0005721
385	Ty Particles vaccine adjuvant	1	VO_0001352
386	U-Omp19 and alum	0	VO_0005722
387	UM-1098	0	VO_0005282
388	UM-3003	0	VO_0005354
389	UM-3004	0	VO_0005353
390	UM-3005	0	VO_0005337
391	V155M	0	VO_0005735
392	VISA	0	VO_0005723
393	VLP@Silica	0	VO_0005732
394	VSA-1	0	VO_0005326
395	VSA-2	0	VO_0005325
396	VSA-3 Adjuvant	2	VO_0001266
Total		417 (unique ones)

Vaccines with adjuvants by vaccine targeted pathogens or diseases

Pathogen or disease	No. of pathogen species	DNA vaccine	Toxoid vaccine	Subunit vaccine	Subunit vaccine + Inactivated or "killed" vaccine	Conjugate vaccine	Inactivated or "killed" vaccine	Recombinant vector vaccine	Live, attenuated vaccine	Fusion protein with adjuvant	Other	trivalent human seasonal influenza vaccine (TIV)	Prime-boost vaccine with DNA vaccine priming	Total
G- bacterium	22/51	2	6	97	11	7	2	6	0	0	0	0	0	131
G+ bacterium	11/17	2	26	39	17	6	4	1	0	1	0	0	0	96
parasite	15/25	6	0	52	0	0	1	4	1	0	0	0	2	66
Allergy	1/1	0	0	1	0	0	0	0	0	0	0	0	0	1
Cancer	1/1	7	0	12	0	1	0	8	1	0	4	0	0	33
Atherosclerosis	1/1	0	0	2	0	0	0	0	0	0	0	0	0	2
virus	28/115	2	0	44	11	0	23	1	3	0	0	1	0	85
fungus	1/1	0	0	3	0	0	0	0	0	0	0	0	0	3
Total	80/212	19	32	250	39	14	30	20	5	1	4	1	2	417

Click here for the list of vaccines that use two or more adjuvants.