VIOLIN: Vaccine Investigation and Online Information Network

Vaxjo: Vaccine Adjuvants

Currently, Vaxjo includes 448 vaccine adjuvants. The detailed curated data is shown below:

Index	Vaccine Adjuvant Name	No. of associated vaccines	VO ID
1	1P7	0	VO_0005516
2	1V270	1	VO_0005270
3	1Z105	0	VO_0005766
4	2B182C	0	VO_0005271
5	2E151	0	VO_0005281
6	2F52	1	VO_0005303
7	2G023A	0	VO_0006097
8	2GO53	0	VO_0006098
9	3DSNA	0	VO_0005517
10	3M-052-AF	0	VO_0005474
11	3M-052-Alum	0	VO_0005387
12	3M-052-SE	0	VO_0005386
13	3pRNA	0	VO_0005518
14	7DW8-5	0	VO_0005515
15	A-910823	0	VO_0006103
16	AAV-IL-27	0	VO_0005729
17	Abisco-100 vaccine adjuvant	1	VO_0001334
18	Ace-DEX	0	VO_0005753
19	ACM-CPG	0	VO_0006106
20	Ad-p53	0	VO_0005738
21	Ad-SLC	0	VO_0005739
22	Adamantylamide Dipeptide Vaccine Adjuvant	1	VO_0000559
23	Adjumer	1	VO_0000351
24	Adjuplex+GLA	0	VO_0005302
25	Adjuvax	0	VO_0005356
26	ADP-ribosylating adjuvant	0	VO_0005520
27	Advax	1	VO_0005207
28	Advax-CpG	0	VO_0005357
29	Advax-CpG55.2	0	VO_0005324
30	AF03	1	VO_0001330
31	AH:CpG	0	VO_0005521
32	Aikejia	0	VO_0005522
33	Al-BSA-Ce6 NPs	0	VO_0005523
34	Alarmin IL-33	0	VO_0005524
35	Albumin-heparin microparticles vaccine adjuvant	0	VO_0001335
36	ALF	0	VO_0005525
37	ALFQ	0	VO_0006096
38	Algal Glucan	0	VO_0001285
39	Algammulin	1	VO_0001286
40	Algel-IMDG	0	VO_0005526
41	Alhydrogel	13	VO_0001241
42	Alhydroxiquim-II	1	VO_0005301
43	AlO(OH)-polymer nanoparticles	0	VO_0005527
44	AlT3	0	VO_0005300
45	AlT4	0	VO_0005299
46	Alum and IL-10	0	VO_0005528
47	Alum/CpG-based formulation	0	VO_0005529
48	aluminum hydroxide vaccine adjuvant	63	VO_0000127
49	aluminum phosphate vaccine adjuvant	49	VO_0000128
50	aluminum potassium sulfate adjuvant	6	VO_0001240
51	Aluminum vaccine adjuvant	14	VO_0000884
52	amorphous aluminum hydroxyphosphate sulfate adjuvant	2	VO_0001323
53	AmpB	0	VO_0005530
54	ANXA2	0	VO_0005531
55	AP adjuvant	0	VO_0005532
56	APS	0	VO_0005533
57	Arlacel A	1	VO_0000191
58	AS-2 vaccine adjuvant	4	VO_0001264
59	AS01	0	VO_0005534
60	AS01B	1	VO_0005358
61	AS02A	0	VO_0005359
62	AS03	2	VO_0001320
63	AS04	1	VO_0001265
64	AS15	0	VO_0005741
65	AS1517499	0	VO_0005742
66	ASPPR	0	VO_0005769
67	Avridine®	1	VO_0001288
68	B7-2 vaccine adjuvant	1	VO_0001337
69	Babassu aqueous extract	0	VO_0005535
70	Bay R1005	1	VO_0001287
71	BECC438b	0	VO_0005298
72	BECC438s	0	VO_0005297
73	BECC470b	0	VO_0005296
74	BECC470s	0	VO_0005383
75	BI-Eng2	0	VO_0005507
76	BI-Eng2+Adjuplex	0	VO_0005508
77	BLP	0	VO_0005770
78	Bordetella pertussis component Vaccine Adjuvant	3	VO_0000193
79	Bupivacaine vaccine adjuvant	0	VO_0001338
80	BVP22	0	VO_0005536
81	BX795	0	VO_0005771
82	c-di-AMP	0	VO_0005731
83	C3 adjuvant	0	VO_0005537
84	C5a	0	VO_0005772
85	C60(OH)22	0	VO_0005538
86	CA-CpG	0	VO_0005539
87	CAF-01	0	VO_0005483
88	CAF-09b	0	VO_0005473
89	CAF04	0	VO_0005540
90	CAF05	0	VO_0005541
91	CAF06	0	VO_0005542
92	CAF19	0	VO_0005543
93	CAF23	0	VO_0005544
94	CAF24a	0	VO_0005545
95	Calcium Phosphate Gel	0	VO_0001289
96	Calcium phosphate vaccine adjuvant	1	VO_0000131
97	Candida skin test reagent	0	VO_0005546
98	CaPNP (CaPtivant)(TM)	0	VO_0005295
99	carbon-silica nanocomposite	0	VO_0005547
100	CARP-1	0	VO_0005768
101	CARP-2	0	VO_0005775
102	caspase-1	0	VO_0005548
103	Cationic Liposomal Vaccine Adjuvant	2	VO_0001262
104	Cationic liposome-DNA complex JVRS-100	1	VO_0001339
105	CBP-12	0	VO_0005549
106	CCL19	0	VO_0005550
107	CCL21 and IL1β	0	VO_0005551
108	CCL3	0	VO_0005553
109	CCL34	0	VO_0005554
110	CCL5 adjuvant	0	VO_0005555
111	CD226	0	VO_0005556
112	CDG	0	VO_0005557
113	CGAMP	0	VO_0005558
114	Chitin	0	VO_0005559
115	Chitosan	0	VO_0005360
116	Cholera toxin	17	VO_0000143
117	Cholera toxin B subunit	6	VO_0001242
118	CITCO	0	VO_0005560
119	CL429	0	VO_0005573
120	CnB	0	VO_0005574
121	Corynebacterium-derived P40 Vaccine Adjuvant	1	VO_0000146
122	CoVaccine HT™	0	VO_0005575
123	Cowpea Mosaic Virus	0	VO_0006107
124	CPDI-01	0	VO_0005330
125	CPDI-02	0	VO_0006093
126	CpG 1018	0	VO_0005514
127	CPG 7909	0	VO_0005576
128	CpG andDcMNPs	0	VO_0005577
129	CpG DNA Vaccine Adjuvant	15	VO_0001237
130	CpG M362	0	VO_0005578
131	CpG oligodeoxynucleotide 1826	0	VO_0005579
132	CpG-MUC1-hydrogel	0	VO_0005580
133	CpG-ODN and Coa-ASC16	0	VO_0005581
134	CpG55.2	0	VO_0006094
135	CRL1005	2	VO_0001318
136	Cry proteins	0	VO_0005582
137	CS3 adjuvant	0	VO_0005583
138	CTA	0	VO_0005584
139	CTA1-DD gene fusion protein	2	VO_0001290
140	CTA1-M2e-DD	0	VO_0005585
141	CTA2B	0	VO_0005586
142	CTB	0	VO_0005587
143	curcumin	0	VO_0005588
144	Curdlan	0	VO_0005767
145	CVC1302	0	VO_0005589
146	CXCL10-mucin-GPI	0	VO_0005590
147	CXCL11	0	VO_0005591
148	CXCL11-Fc	0	VO_0005592
149	CXCL9	0	VO_0005593
150	CyPA	0	VO_0005594
151	CYT387	0	VO_0005774
152	D-mannose	0	VO_0005595
153	D-Murapalmitine	0	VO_0001304
154	D-Murapalmitine	0	VO_0001305
155	DAI	0	VO_0005596
156	DDA Adjuvant	3	VO_0001261
157	DDO (Defective derived oligonucleotide)	1	VO_0005294
158	DHEA vaccine adjuvant	1	VO_0001340
159	dibutyl phthalate	0	VO_0005369
160	DL-PGL (Polyester poly (DL-lactide-co-glycolide)) vaccine adjuvant	1	VO_0001341
161	DLinDMA	0	VO_0005597
162	dmLT (double mutant of heat-labile E.coli)	0	VO_0005329
163	DOC/Alum Complex	1	VO_0001291
164	DOTAP and DP7-C liposomes	0	VO_0005598
165	DP-D	0	VO_0005733
166	E. coli heat-labile toxin, LT	3	VO_0001322
167	Em	0	VO_0005293
168	EmT4	0	VO_0005292
169	EP67	0	VO_0005765
170	epigallocatechin-3-gallate	0	VO_0005599
171	Etx B subunit Adjuvant	2	VO_0001272
172	Evax-B	0	VO_0005510
173	Evax-S	0	VO_0005511
174	FimH	0	VO_0005600
175	FLAB-PSPA	0	VO_0005601
176	Flagellin	1	VO_0001331
177	FLIC	0	VO_0005602
178	Flt-3 ligand	0	VO_0005603
179	Fos47	0	VO_0005291
180	Freund's Complete Adjuvant	45	VO_0000139
181	Freund's Incomplete Adjuvant	46	VO_0000142
182	Fuc-Sc	0	VO_0005604
183	G2	0	VO_0005605
184	G3	0	VO_0005606
185	Gamma Inulin	1	VO_0001292
186	GC@ICG nanoparticle	0	VO_0005607
187	GDQ	0	VO_0005754
188	Gel-gffy	0	VO_0005608
189	Gerbu Adjuvant	1	VO_0001293
190	GITRL	0	VO_0005609
191	GLA-3M-052-LS	0	VO_0005385
192	GLA-AF	0	VO_0005424
193	GLA-Alum	0	VO_0006099
194	GLA-LSQ	0	VO_0005421
195	GLA-SE	0	VO_0005420
196	glycated chitosan	0	VO_0005610
197	glycerol	0	VO_0005370
198	GM-CSF	27	VO_0001294
199	GM3	0	VO_0005611
200	GMDP	1	VO_0001295
201	gp63	0	VO_0005612
202	GPI-0100	0	VO_0005763
203	GPI-CCL28	0	VO_0005552
204	Granules of mast cells	0	VO_0005613
205	Granulysin	0	VO_0005614
206	Graphene oxide	0	VO_0005615
207	HAV-aCNP	0	VO_0005616
208	HBcAg	0	VO_0005617
209	HBHA	0	VO_0005618
210	hexosomes	0	VO_0005619
211	HIV-1 protease	0	VO_0005620
212	HMBA	0	VO_0005621
213	HMGB1	0	VO_0005622
214	HP-?-CD	0
215	Hsp65	0	VO_0005761
216	HVJ-Envelope	0	VO_0005762
217	IBL027	0	VO_0005623
218	IFN-α	0	VO_0005624
219	IFNβ	0	VO_0005625
220	IL-12 Vaccine Adjuvant	14	VO_0001147
221	IL-12-MOP	0	VO_0005509
222	IL-15	1	VO_0001342
223	IL-15 plasmid vaccine adjuvant	0	VO_0000384
224	IL-18	0	VO_0005627
225	IL-1R1	0	VO_0005628
226	IL-21	0	VO_0005629
227	IL-27	0	VO_0005630
228	IL-33	0	VO_0005631
229	IL-36	0	VO_0005632
230	IL-4	0	VO_0005633
231	IL-7-Fc	0	VO_0005634
232	Imiquimod	1	VO_0001328
233	Immunoliposomes Containing Antibodies to Costimulatory Molecules	1	VO_0001343
234	IMP321	0	VO_0005635
235	INI-2002	0	VO_0005290
236	INI-2004	0	VO_0005289
237	INI-4001	0	VO_0005288
238	Interleukin-1β	1	VO_0001297
239	Interleukin-2	1	VO_0001298
240	Interleukin-7	1	VO_0001299
241	IP-PA1	0	VO_0005636
242	IPMPs	0	VO_0005637
243	iron oxide nanoparticles	0	VO_0005638
244	IRX-2	0	VO_0005639
245	ISCOM(s)™	2	VO_0000757
246	ISCOMATRIX®	1	VO_0001333
247	ISG15	0	VO_0005640
248	α-galactosylceramide	0	VO_0005724
249	α-GalCer and MPL	0	VO_0005725
250	K3-SPG	0	VO_0005641
251	Killed Corynebacterium parvum Vaccine Adjuvant	2	VO_0001259
252	KML-B	0	VO_0005642
253	Kynurenine	0	VO_0005643
254	L-NAME	0	VO_0005644
255	L-siRNA	0	VO_0005645
256	L. polysaccharide	0	VO_0005746
257	LAB EPS	0	VO_0005726
258	LCP	0	VO_0005736
259	Levamisole	0	VO_0005760
260	LIGHT	0	VO_0005646
261	Lipopolysaccharide Vaccine Adjuvant	1	VO_0000181
262	Liposomes	2	VO_0000366
263	Listeriolysin O	0	VO_0005647
264	LiT4	0	VO_0005287
265	LMQ	0	VO_0006092
266	Loxoribine	1	VO_0001300
267	LP-GMP	0	VO_0005648
268	LQ	0	VO_0005390
269	LT-IIb	0	VO_0005649
270	LTA1	0	VO_0005355
271	LTK63 Vaccine Mutant Adjuvant	2	VO_0001251
272	LTR192G Vaccine Adjuvant	6	VO_0001321
273	LTR72 vaccine adjuvant	1	VO_0001344
274	Man-TLR7	0	VO_0005650
275	Mannadjuvant	0	VO_0005286
276	MAS-1	0	VO_0005471
277	Mast Cell Activator Small Muscles	0	VO_0005381
278	Mastoparan 7	0	VO_0005380
279	Matrix-M	2	VO_0005206
280	Matrix-S	1	VO_0001324
281	MCP-3	0	VO_0005651
282	MDA5	0	VO_0005652
283	MDP-1	0	VO_0005653
284	ME-F-1051	0	VO_0005512
285	ME-F-1122	0	VO_0005513
286	mesoporous silica nanoparticle	0	VO_0005654
287	MF59	5	VO_0001301
288	MicroCyrstalline Tyrosine® (MCT)	0	VO_0005419
289	MIP-1alpha	0	VO_0005759
290	MIP-2	0	VO_0005655
291	MiT4	0	VO_0005285
292	MMG-1	0	VO_0005656
293	Montanide 103	0	VO_0000192
294	Montanide IMS 1313	0	VO_0000192
295	Montanide Incomplete Seppic Adjuvant	1	VO_0001269
296	Montanide ISA 206	0	VO_0005362
297	Montanide ISA 50	0	VO_0005363
298	Montanide ISA 51	2	VO_0001270
299	Montanide ISA 720	6	VO_0001268
300	MPL + TDM	0	VO_0005367
301	MPL-SE vaccine adjuvant	2	VO_0001345
302	MPL™ Adjuvant	9	VO_0001250
303	MSP-102	0	VO_0005657
304	MTP-PE Liposomes	2	VO_0001302
305	MUC1 based adjuvant-protein-antigen	0	VO_0005658
306	Murabutide	0	VO_0005752
307	Murametide	0	VO_0001303
308	Muramyl Dipeptide Adjuvant	1	VO_0000187
309	Myd88	0	VO_0005660
310	MyD88/CD40	0	VO_0005659
311	NADA	0	VO_0005755
312	NAGO	1	VO_0001306
313	Naltrexone	0	VO_0005661
314	NanoAlum	0	VO_0005475
315	nanoemulsion vaccine adjuvant	3	VO_0001319
316	Nanostructured Lipid Carrier (NLC)	0	VO_0005476
317	NanoVax/NE01	0	VO_0005284
318	Nexavant	0	VO_0006108
319	Non-Ionic Surfactant Vesicles	1	VO_0001307
320	non-toxic mutant E112K of Cholera Toxin mCT-E112K	1	VO_0001347
321	NP DNA adjuvant	0	VO_0005662
322	NP-3pRNA-CpG	0	VO_0005663
323	NP-R@M-M	0	VO_0005664
324	NS-TLR	0	VO_0005749
325	OK-432	0	VO_0005665
326	OMPC-TLR2	0	VO_0005666
327	Ophiopogonin D	0	VO_0005667
328	OVA-csNLCs	0	VO_0005668
329	OVA-LNPs	0	VO_0005669
330	P2Et	0	VO_0005670
331	PAA:nanoalum	0	VO_0005671
332	Pam3Cys	0	VO_0005371
333	PAMK	0	VO_0005672
334	PAPE	0	VO_0005673
335	pcIFN-gamma	0	VO_0005727
336	PEI-PPAS	0	VO_0005674
337	PET Lipid A	0	VO_0005675
338	PHAD	0	VO_0005757
339	PhotothermalPhage	0	VO_0005676
340	PI-RI	0	VO_0005677
341	PI-sRI	0	VO_0005678
342	PIKA	0	VO_0005379
343	Pinaceae-derived nanoemulsions	0	VO_0005679
344	PLA-b-P(NAS-co-NVP)	0	VO_0005680
345	Platycodin D	0	VO_0005682
346	PLGA	0	VO_0005683
347	PMMA	1	VO_0001308
348	PNPS-0.3	0	VO_0005685
349	Poly-ϵ-caprolactone and chitosan nanoparticles	0	VO_0005686
350	Polyethyleneimine	0	VO_0005687
351	Polygen Vaccine Adjuvant	1	VO_0001273
352	PolyIC:LC	0	VO_0005688
353	polysorbitol-co-PEI polymer	0	VO_0005689
354	porous silicon microparticle	0	VO_0005690
355	Precision Vaccines Program (PVP)-037	0	VO_0005382
356	Precision Vaccines Program (PVP)-057	0	VO_0006105
357	Pro-LNG-S	0	VO_0005472
358	Propionibacterium acnes(P. acnes)	0	VO_0005691
359	Protein Cochleates	1	VO_0001309
360	pSPreS2	0	VO_0005692
361	QS-17 and18	0	VO_0005693
362	QS-21	1	VO_0001310
363	Quil-A vaccine adjuvant	6	VO_0001263
364	RALDH2	0	VO_0005694
365	RC529 vaccine adjuvant	1	VO_0001239
366	RC529-AF	0	VO_0001249
367	rcIL-15	0	VO_0005728
368	Recombinant hIFN-gamma/Interferon-g	1	VO_0001296
369	Rehydragel HPA	1	VO_0001311
370	Rehydragel LV	1	VO_0001312
371	Resiquimod	0	VO_0001329
372	retinoic acid and IL-15	0	VO_0005695
373	rhIL-7 adjuvant	0	VO_0005730
374	rHP-NAP	0	VO_0005696
375	Ribi Vaccine Adjuvant	11	VO_0001238
376	RNadjuvant	0	VO_0005697
377	rNDV-mOX40L	0	VO_0005698
378	Rotavirus VP6	0	VO_0005699
379	rOv-ASP-1	0	VO_0005327
380	Rv3628	0	VO_0005700
381	S-540956	0	VO_0006104
382	SAF-1	1	VO_0001349
383	SAG1 and TLR-5 ligand	0	VO_0005701
384	Saponin Monophosphoryl Lipid-A Nanoparticles	0	VO_0006095
385	Saponin Vaccine Adjuvant	4	VO_0001267
386	SBAS2	0	VO_0005750
387	Sclavo peptide	0	VO_0001313
388	Sendai Proteoliposomes, Sendai-containing Lipid Matrices	0	VO_0001350
389	Shrimp anti-lipopolysaccharide factor	0	VO_0005702
390	SLA-AF	0	VO_0005482
391	SLA-Alum	0	VO_0006100
392	SLA-LSQ	0	VO_0005422
393	SLA-SE	0	VO_0005423
394	SMQ	0	VO_0005756
395	solid nanoemulsion	0	VO_0005703
396	solid-in-oil-in-water emulsion	0	VO_0005704
397	sPD-1	0	VO_0005705
398	Specol	1	VO_0001314
399	sPLA2	0	VO_0005706
400	spontaneous nanoliposome antigen particleization	0	VO_0005707
401	SPT (Antigen Formulation)	1	VO_0001315
402	SQ	0	VO_0005389
403	Squalene-based Adjuvants	1	VO_0000190
404	ST101036	0	VO_0005758
405	Stable Emulsion (SE) vaccine adjuvant	0	VO_0006101
406	Stearyl Tyrosine	1	VO_0001316
407	sticholysin II	0	VO_0005708
408	STING V155M	0	VO_0005735
409	SWE	0	VO_0005388
410	Syntex Adjuvant Formulation	0	VO_0005368
411	synthetic melanin	0	VO_0005709
412	t-NanoCpG	0	VO_0005710
413	T-vant	0	VO_0005375
414	T7-alum	0	VO_0005711
415	T7-EA	0	VO_0005734
416	Taishan Robinia Pseudoacacia polysaccharides	0	VO_0005712
417	TDM	0	VO_0005713
418	TF-Al	0	VO_0005714
419	TFPR1	0	VO_0005751
420	Theramide®	1	VO_0001317
421	Threonyl muramyl dipeptide (TMDP)	1	VO_0001351
422	Thymosin alpha-1	0	VO_0005715
423	TiterMax Gold Adjuvant	3	VO_0001260
424	TLR3	1	VO_0001332
425	TLR7 agonist and NOD2 agonist	0	VO_0005717
426	TLR7-8 RNA ligands	0	VO_0005718
427	Tomatine	0	VO_0005364
428	TQL-1055	0	VO_0005283
429	TRAC478	0	VO_0005384
430	trichosanthin	0	VO_0005719
431	TRIF	0	VO_0005720
432	Tumour-derived exosomes (TEXs)	0	VO_0005721
433	Tween 80	0	VO_0005764
434	Ty Particles vaccine adjuvant	1	VO_0001352
435	U-Omp19 and alum	0	VO_0005722
436	UM-1098	0	VO_0005282
437	UM-3003	0	VO_0005354
438	UM-3004	0	VO_0005353
439	UM-3005	0	VO_0005337
440	Vaxfectin	0	VO_0005372
441	VISA	0	VO_0005723
442	VLP@Silica	0	VO_0005732
443	VSA-1	0	VO_0005326
444	VSA-2	0	VO_0005325
445	VSA-3 Adjuvant	2	VO_0001266
446	xanthan gum	0	VO_0000938
447	XtendIII	0	VO_0005366
448	Zymosan	0	VO_0005365
Total		420 (unique ones)

Vaccines with adjuvants by vaccine targeted pathogens or diseases

Pathogen or disease	No. of pathogen species	DNA vaccine	Toxoid vaccine	Subunit vaccine	Subunit vaccine + Inactivated or "killed" vaccine	Conjugate vaccine	Inactivated or "killed" vaccine	Recombinant vector vaccine	Live, attenuated vaccine	Fusion protein with adjuvant	Other	trivalent human seasonal influenza vaccine (TIV)	protein-nanoparticle vaccine	Prime-boost vaccine with DNA vaccine priming	Total
G- bacterium	22/51	2	6	97	11	7	2	6	0	0	0	0	0	0	131
G+ bacterium	11/17	2	26	39	17	6	4	1	0	1	0	0	0	0	96
parasite	15/25	6	0	54	0	0	1	4	1	0	0	0	1	2	69
Allergy	1/1	0	0	1	0	0	0	0	0	0	0	0	0	0	1
Cancer	1/1	7	0	12	0	1	0	8	1	0	4	0	0	0	33
Atherosclerosis	1/1	0	0	2	0	0	0	0	0	0	0	0	0	0	2
virus	28/115	2	0	44	11	0	23	1	3	0	0	1	0	0	85
fungus	1/1	0	0	3	0	0	0	0	0	0	0	0	0	0	3
Total	80/212	19	32	252	39	14	30	20	5	1	4	1	1	2	420

Click here for the list of vaccines that use two or more adjuvants.