VIOLIN: Vaccine Investigation and Online Information Network

Vaxjo: Vaccine Adjuvants

Currently, Vaxjo includes 435 vaccine adjuvants. The detailed curated data is shown below:

Index	Vaccine Adjuvant Name	No. of associated vaccines	VO ID
1	1P7	0	VO_0005516
2	1V270	1	VO_0005270
3	2B182C	0	VO_0005271
4	2E151	0	VO_0005281
5	2F52	1	VO_0005303
6	2G023A	0	VO_0006097
7	2GO53	0	VO_0006098
8	3DSNA	0	VO_0005517
9	3M-052-AF	0	VO_0005474
10	3M-052-Alum	0	VO_0005387
11	3M-052-SE	0	VO_0005386
12	3pRNA	0	VO_0005518
13	7DW8-5	0	VO_0005515
14	A-910823	0	VO_0006103
15	AAHS	0	VO_0005715
16	AAV-IL-27	0	VO_0005729
17	Abisco-100 vaccine adjuvant	1	VO_0001334
18	ACM-CPG	0	VO_0006106
19	Ad-p53	0	VO_0005738
20	Ad-SLC	0	VO_0005739
21	Adamantylamide Dipeptide Vaccine Adjuvant	1	VO_0000559
22	Adjumer	1	VO_0000351
23	Adjuplex+GLA	0	VO_0005302
24	ADP-ribosylating adjuvant	0	VO_0005520
25	Advax	1	VO_0005207
26	Advax-CpG55.2	0	VO_0005324
27	AF03	1	VO_0001330
28	AH:CpG	0	VO_0005521
29	Aikejia	0	VO_0005522
30	Alarmin IL-33	0	VO_0005524
31	Albumin-heparin microparticles vaccine adjuvant	0	VO_0001335
32	ALF	0	VO_0005525
33	ALFQ	0	VO_0006096
34	Algal Glucan	0	VO_0001285
35	Algammulin	1	VO_0001286
36	Algel-IMDQ	0	VO_0005526
37	Alhydrogel	13	VO_0001241
38	Alhydroxiquim-II	1	VO_0005301
39	AlO(OH)-polymer nanoparticles	0	VO_0005527
40	AlT3	0	VO_0005300
41	AlT4	0	VO_0005299
42	Alum and IL-10	0	VO_0005528
43	Alum-TLR7	0
44	Alum/CpG-based formulation	0
45	aluminum hydroxide vaccine adjuvant	63	VO_0000127
46	aluminum phosphate vaccine adjuvant	49	VO_0000128
47	aluminum potassium sulfate adjuvant	6	VO_0001240
48	Aluminum vaccine adjuvant	14	VO_0000884
49	amorphous aluminum hydroxyphosphate sulfate adjuvant	2	VO_0001323
50	AmpB	0	VO_0005530
51	AP adjuvant	0	VO_0005532
52	APS	0	VO_0005533
53	Arlacel A	1	VO_0000191
54	AS-2 vaccine adjuvant	4	VO_0001264
55	AS01	0	VO_0005534
56	AS01B	0
57	AS02	4	VO_0001264
58	AS02A	0
59	AS03	2	VO_0001320
60	AS04	1	VO_0001265
61	AS15	0	VO_0005741
62	AS1517499	0	VO_0005742
63	ASPPR	0
64	Avridine®	1	VO_0001288
65	B7-2 vaccine adjuvant	1	VO_0001337
66	Babassu aqueous extract	0	VO_0005535
67	Bay R1005	1	VO_0001287
68	BECC438b	0	VO_0005298
69	BECC438s	0	VO_0005297
70	BECC470b	0	VO_0005296
71	BECC470s	0	VO_0005383
72	BI-Eng2	0	VO_0005507
73	BI-Eng2+Adjuplex	0	VO_0005508
74	BLP	0
75	Bordetella pertussis component Vaccine Adjuvant	3	VO_0000193
76	Bupivacaine vaccine adjuvant	0	VO_0001338
77	BVP22	0	VO_0005536
78	BX795	0
79	c-di-AMP	0	VO_0005731
80	C3 adjuvant	0	VO_0005537
81	C5a	0
82	C60(OH)22	0	VO_0005538
83	CA-CpG	0	VO_0005539
84	CAF-01	0	VO_0005483
85	CAF-09b	0	VO_0005473
86	CAF04	0	VO_0005540
87	CAF05	0	VO_0005541
88	CAF06	0	VO_0005542
89	CAF19	0	VO_0005543
90	CAF23	0	VO_0005544
91	CAF24a	0	VO_0005545
92	Calcium Phosphate Gel	0	VO_0001289
93	Calcium phosphate vaccine adjuvant	1	VO_0000131
94	Candida skin test reagent	0	VO_0005546
95	CaPNP (CaPtivant)(TM)	0	VO_0005295
96	carbon-silica nanocomposite	0	VO_0005547
97	CARP-1	0	VO_0005768
98	CARP-2	0	VO_0005775
99	caspase-1	0	VO_0005548
100	Cationic adjuvant formulations (CAFs)	0	VO_0005681
101	Cationic Liposomal Vaccine Adjuvant	2	VO_0001262
102	Cationic liposome-DNA complex JVRS-100	1	VO_0001339
103	CBP-12	0	VO_0005549
104	CCL19	0	VO_0005550
105	CCL21 and IL1β	0	VO_0005551
106	CCL3	0	VO_0005553
107	CCL34	0	VO_0005554
108	CCL5 adjuvant	0	VO_0005555
109	CD226	0	VO_0005556
110	CDG	0	VO_0005557
111	CGAMP	0	VO_0005558
112	Chitin	0	VO_0005559
113	Chitosan	0	VO_0005360
114	Cholera toxin	17	VO_0000143
115	Cholera toxin B subunit	6	VO_0001242
116	CITCO	0	VO_0005560
117	CL429	0	VO_0005573
118	CnB	0	VO_0005574
119	Corynebacterium-derived P40 Vaccine Adjuvant	1	VO_0000146
120	CoVaccine HT™	0	VO_0005575
121	Cowpea Mosaic Virus	0	VO_0006107
122	CPDI-01	0	VO_0005330
123	CPDI-02	0	VO_0006093
124	CPG 7909	0	VO_0005576
125	CpG andDcMNPs	0	VO_0005577
126	CpG DNA Vaccine Adjuvant	15	VO_0001237
127	CpG M362	0	VO_0005578
128	CpG oligodeoxynucleotide 1826	0	VO_0005579
129	CpG-MUC1-hydrogel	0	VO_0005580
130	CpG-ODN and Coa-ASC16	0	VO_0005581
131	CpG-ODN Shapes Alum Adjuvant	0
132	CRL1005	2	VO_0001318
133	Cry proteins	0	VO_0005582
134	CS3 adjuvant	0	VO_0005583
135	CTA	0	VO_0005584
136	CTA1-DD gene fusion protein	2	VO_0001290
137	CTA1-M2e-DD	0	VO_0005585
138	CTA2B	0	VO_0005586
139	CTB	0	VO_0005587
140	curcumin	0	VO_0005588
141	Curdlan	0	VO_0005767
142	CVC1302	0	VO_0005589
143	CXCL10	0
144	CXCL10-mucin-GPI	0	VO_0005590
145	CXCL11	0	VO_0005591
146	CXCL11-Fc	0	VO_0005592
147	CXCL9	0	VO_0005593
148	CyPA	0	VO_0005594
149	CYT387	0	VO_0005774
150	D-mannose	0	VO_0005595
151	D-Murapalmitine	0	VO_0001305
152	DAI	0	VO_0005596
153	DDA Adjuvant	3	VO_0001261
154	DDO (Defective derived oligonucleotide)	1	VO_0005294
155	delta-inulin	0	VO_0005723
156	DHEA vaccine adjuvant	1	VO_0001340
157	dibutyl phthalate	0	VO_0005369
158	DL-PGL (Polyester poly (DL-lactide-co-glycolide)) vaccine adjuvant	1	VO_0001341
159	DLinDMA	0	VO_0005597
160	dmLT (double mutant of heat-labile E.coli)	0	VO_0005329
161	DOC/Alum Complex	1	VO_0001291
162	DOTAP and DP7-C liposomes	0	VO_0005598
163	E. coli heat-labile toxin, LT	3	VO_0001322
164	EGCG	0	VO_0005599
165	Em	0	VO_0005293
166	EmT4	0	VO_0005292
167	EP67	0	VO_0005765
168	epigallocatechin-3-gallate	0	VO_0005599
169	Etx B subunit Adjuvant	2	VO_0001272
170	Evax-B	0	VO_0005510
171	Evax-S	0	VO_0005511
172	FimH	0	VO_0005600
173	FLAB-PSPA	0	VO_0005601
174	Flagellin	1	VO_0001331
175	FLIC	0	VO_0005602
176	Flt-3 ligand	0	VO_0005603
177	Fos47	0	VO_0005291
178	Freund's Complete Adjuvant	45	VO_0000139
179	Freund's Incomplete Adjuvant	46	VO_0000142
180	Fuc-Sc	0	VO_0005604
181	G2	0	VO_0005605
182	G3	0	VO_0005606
183	Gamma Inulin	1	VO_0001292
184	GC@ICG nanoparticle	0	VO_0005607
185	GDQ	0	VO_0005754
186	Gel-gffy	0	VO_0005608
187	Gerbu Adjuvant	1	VO_0001293
188	GITRL	0	VO_0005609
189	GLA-3M-052-LS	0	VO_0005385
190	GLA-AF	0	VO_0005424
191	GLA-Alum	0	VO_0006099
192	GLA-LSQ	0	VO_0005421
193	GLA-SE	0	VO_0005420
194	glycated chitosan	0	VO_0005610
195	glycerol	0	VO_0005370
196	GM-CSF	27	VO_0001294
197	GM3	0	VO_0005611
198	GMDP	1	VO_0001295
199	gp63	0	VO_0005612
200	GPI-0100	0	VO_0005763
201	GPI-CCL28	0	VO_0005552
202	Granules of mast cells	0	VO_0005613
203	Granulysin	0	VO_0005614
204	Graphene oxide	0	VO_0005615
205	HAV-aCNP	0	VO_0005616
206	HBcAg	0	VO_0005617
207	HBHA	0	VO_0005618
208	HBsAg	0	VO_0005779
209	hexosomes	0	VO_0005619
210	HIV-1 protease	0	VO_0005620
211	HMBA	0	VO_0005621
212	HMGB1	0	VO_0005622
213	HP-?-CD	0
214	Hsp65	0	VO_0005761
215	HVJ-Envelope	0	VO_0005762
216	IBL027	0	VO_0005623
217	IFN-α	0	VO_0005624
218	IFNβ	0	VO_0005625
219	IL-12 Vaccine Adjuvant	14	VO_0001147
220	IL-12-MOP	0	VO_0005509
221	IL-15	1	VO_0001342
222	IL-15 plasmid vaccine adjuvant	0	VO_0000384
223	IL-18	0	VO_0005627
224	IL-1R1	0	VO_0005628
225	IL-21	0	VO_0005629
226	IL-27	0	VO_0005630
227	IL-33	0	VO_0005631
228	IL-36	0	VO_0005632
229	IL-4	0	VO_0005633
230	IL-7	1	VO_0001299
231	IL-7-Fc	0	VO_0005634
232	IL15	1	VO_0005270
233	Imiquimod	1	VO_0001328
234	Immunoliposomes Containing Antibodies to Costimulatory Molecules	1	VO_0001343
235	IMP321	0	VO_0005635
236	INI-2002	0	VO_0005290
237	INI-2004	0	VO_0005289
238	INI-4001	0	VO_0005288
239	Injectable Excipients	0	VO_0005679
240	Interleukin-1β	1	VO_0001297
241	Interleukin-2	1	VO_0001298
242	Interleukin-7	1	VO_0001299
243	IPMPs	0	VO_0005637
244	iron oxide nanoparticles	0	VO_0005638
245	IRX-2	0	VO_0005639
246	ISCOM(s)™	2	VO_0000757
247	ISCOMATRIX®	1	VO_0001333
248	ISG15	0	VO_0005640
249	α-galactosylceramide	0	VO_0005724
250	α-GalCer and MPL	0	VO_0005725
251	K3-SPG	0	VO_0005641
252	Killed Corynebacterium parvum Vaccine Adjuvant	2	VO_0001259
253	KML-B	0	VO_0005642
254	Kynurenine	0	VO_0005643
255	L-NAME	0	VO_0005644
256	L-siRNA	0	VO_0005645
257	L. polysaccharide	0	VO_0005746
258	LAB EPS	0	VO_0005726
259	LAG-3	0
260	LCP	0	VO_0005736
261	Levamisole	0	VO_0005760
262	LIGHT	0	VO_0005646
263	Lipopolysaccharide Vaccine Adjuvant	1	VO_0000181
264	Liposomes	2	VO_0000366
265	Listeriolysin O	0	VO_0005647
266	LiT4	0	VO_0005287
267	LMQ	0	VO_0006092
268	Loxoribine	1	VO_0001300
269	LP-GMP	0	VO_0005648
270	LQ	0	VO_0005390
271	LT(R192G)	6	VO_0001321
272	LT-IIb	0	VO_0005649
273	LTA1	0	VO_0005355
274	LTK63 Vaccine Mutant Adjuvant	2	VO_0001251
275	LTR192G Vaccine Adjuvant	6	VO_0001321
276	LTR72 vaccine adjuvant	1	VO_0001344
277	Man-TLR7	0	VO_0005650
278	Mannadjuvant	0	VO_0005286
279	MAS-1	0	VO_0005471
280	Mast Cell Activator Small Muscles	0	VO_0005381
281	Mastoparan 7	0	VO_0005380
282	Matrix-M	2	VO_0005206
283	Matrix-S	1	VO_0001324
284	MCP-3	0	VO_0005651
285	MDA5	0	VO_0005652
286	MDP-1	0	VO_0005653
287	ME-F-1051	0	VO_0005512
288	ME-F-1122	0	VO_0005513
289	melatonin	0	VO_0005538
290	mesoporous silica nanoparticle	0	VO_0005654
291	MF59	5	VO_0001301
292	MicroCyrstalline Tyrosine® (MCT)	0	VO_0005419
293	MIP-1alpha	0	VO_0005759
294	MIP-2	0	VO_0005655
295	MiT4	0	VO_0005285
296	MMG-1	0	VO_0005656
297	monomeric annexin A2	1	VO_0005270
298	Montanide Incomplete Seppic Adjuvant	1	VO_0001269
299	Montanide ISA 51	2	VO_0001270
300	Montanide ISA 720 Adjuvant	6	VO_0001268
301	MPL	9	VO_0001250
302	MPL + TDM	0
303	MPL-SE vaccine adjuvant	2	VO_0001345
304	MPL™ Adjuvant	9	VO_0001250
305	MSP-102	0	VO_0005657
306	MTP-PE Liposomes	2	VO_0001302
307	Murametide	0	VO_0001303
308	Muramyl Dipeptide Adjuvant	1	VO_0000187
309	Murapalmitine	0	VO_0001304
310	Myd88	0	VO_0005660
311	MyD88/CD40	0	VO_0005659
312	NAGO	1	VO_0001306
313	Naltrexone	0	VO_0005661
314	NanoAlum	0	VO_0005475
315	nanoemulsion vaccine adjuvant	3	VO_0001319
316	Nanostructured Lipid Carrier (NLC)	0	VO_0005476
317	NanoVax/NE01	0	VO_0005284
318	Nexavant	0	VO_0006108
319	Non-Ionic Surfactant Vesicles	1	VO_0001307
320	non-toxic mutant E112K of Cholera Toxin mCT-E112K	1	VO_0001347
321	NP DNA adjuvant	0	VO_0005662
322	NP-3pRNA-CpG	0
323	NP-R@M-M	0	VO_0005664
324	NS-TLR	0	VO_0005749
325	OK-432	0	VO_0005665
326	Ophiopogonin D	0	VO_0005667
327	OVA-csNLCs	0	VO_0005668
328	P2Et	0	VO_0005670
329	PAA:nanoalum	0	VO_0005671
330	PAMK	0	VO_0005672
331	PAPE	0	VO_0005673
332	pcIFN-gamma	0	VO_0005727
333	PCL and chitosan NPs	0
334	PEI-PPAS	0	VO_0005674
335	PET Lipid A	0	VO_0005675
336	PhotothermalPhage	0	VO_0005676
337	PI-RI	0	VO_0005677
338	PI-sRI	0	VO_0005678
339	PIKA	0	VO_0005379
340	Pinaceae-derived nanoemulsions	0	VO_0005679
341	PLA-b-P(NAS-co-NVP)	0	VO_0005680
342	Platycodin D	0	VO_0005682
343	PLGA	0	VO_0005684
344	PMMA	1	VO_0001308
345	Poly(I:C)	1	VO_0001332
346	Poly-ϵ-caprolactone and chitosan nanoparticles	0	VO_0005686
347	Polyethyleneimine	0	VO_0005687
348	Polygen Vaccine Adjuvant	1	VO_0001273
349	PolyIC:LC	0	VO_0005688
350	Polyinosinic-polycytidylic acid	0	VO_0005661
351	polysorbitol-co-PEI polymer	0	VO_0005689
352	porous silicon microparticle	0	VO_0005690
353	Precision Vaccines Program (PVP)-037	0	VO_0005382
354	Precision Vaccines Program (PVP)-057	0	VO_0006105
355	Pro-LNG-S	0	VO_0005472
356	Propionibacterium acnes(P. acnes)	0	VO_0005691
357	Protein Cochleates	1	VO_0001309
358	PRR agonists	0	VO_0005669
359	pSPreS2	0	VO_0005692
360	QS-17 and18	0	VO_0005693
361	QS-21	1	VO_0001310
362	Quil-A vaccine adjuvant	6	VO_0001263
363	RALDH2	0	VO_0005694
364	RC529 vaccine adjuvant	1	VO_0001239
365	rcIL-15	0	VO_0005728
366	Recombinant hIFN-gamma/Interferon-g	1	VO_0001296
367	Rehydragel HPA	1	VO_0001311
368	Rehydragel LV	1	VO_0001312
369	Resiquimod	0	VO_0001329
370	retinoic acid and IL-15	0	VO_0005695
371	rhIL-7 adjuvant	0	VO_0005730
372	Ribi Vaccine Adjuvant	11	VO_0001238
373	RNadjuvant	0	VO_0005697
374	rNDV-mOX40L	0	VO_0005698
375	Rotavirus VP6	0	VO_0005699
376	rOv-ASP-1	0	VO_0005327
377	Rv3628	0	VO_0005700
378	S-540956	0	VO_0006104
379	SAF-1	1	VO_0001349
380	SAG1 and TLR-5 ligand	0	VO_0005701
381	saponin and MPLA nanoparticles	0	VO_0006095
382	Saponin Monophosphoryl Lipid-A Nanoparticles	0	VO_0006095
383	Saponin Vaccine Adjuvant	4	VO_0001267
384	SBAS2	0	VO_0005750
385	Sclavo peptide	0	VO_0001313
386	Sendai Proteoliposomes, Sendai-containing Lipid Matrices	0	VO_0001350
387	Shrimp anti-lipopolysaccharide factor	0	VO_0005702
388	SLA-AF	0	VO_0005482
389	SLA-Alum	0	VO_0006100
390	SLA-LSQ	0	VO_0005422
391	SLA-SE	0	VO_0005423
392	solid nanoemulsion	0	VO_0005703
393	solid-in-oil-in-water emulsion	0	VO_0005704
394	sPD-1	0	VO_0005705
395	Specol	1	VO_0001314
396	spontaneous nanoliposome antigen particleization	0	VO_0005707
397	SPT (Antigen Formulation)	1	VO_0001315
398	SQ	0	VO_0005389
399	Squalene-based Adjuvants	1	VO_0000190
400	Stable Emulsion (SE) vaccine adjuvant	0	VO_0006101
401	Stearyl Tyrosine	1	VO_0001316
402	sticholysin \|\|	0	VO_0005708
403	SWE	0	VO_0005388
404	t-NanoCpG	0	VO_0005710
405	T-vant	0	VO_0005375
406	T7-alum	0	VO_0005711
407	Taishan Robinia Pseudoacacia polysaccharides	0	VO_0005712
408	TDM	0	VO_0005713
409	TF-Al	0	VO_0005714
410	Theramide®	1	VO_0001317
411	Threonyl muramyl dipeptide (TMDP)	1	VO_0001351
412	TiterMax Gold Adjuvant	3	VO_0001260
413	TLR-7 andTLR-8 Agonist	0	VO_0005674
414	TLR3	1	VO_0001332
415	TLR4 agonist lipopolysaccharides	1	VO_0005270
416	TLR5	1	VO_0005270
417	TLR7-8 RNA ligands	0	VO_0005718
418	TLRa	0	VO_0005656
419	TQL-1055	0	VO_0005283
420	TRAC478	0	VO_0005384
421	trichosanthin	0	VO_0005719
422	TRIF	0	VO_0005720
423	Tumour-derived exosomes (TEXs)	0	VO_0005721
424	Ty Particles vaccine adjuvant	1	VO_0001352
425	U-Omp19 and alum	0	VO_0005722
426	UM-1098	0	VO_0005282
427	UM-3003	0	VO_0005354
428	UM-3004	0	VO_0005353
429	UM-3005	0	VO_0005337
430	V155M	0	VO_0005735
431	VISA	0	VO_0005723
432	VLP@Silica	0	VO_0005732
433	VSA-1	0	VO_0005326
434	VSA-2	0	VO_0005325
435	VSA-3 Adjuvant	2	VO_0001266
Total		419 (unique ones)

Vaccines with adjuvants by vaccine targeted pathogens or diseases

Pathogen or disease	No. of pathogen species	DNA vaccine	Toxoid vaccine	Subunit vaccine	Subunit vaccine + Inactivated or "killed" vaccine	Conjugate vaccine	Inactivated or "killed" vaccine	Recombinant vector vaccine	Live, attenuated vaccine	Fusion protein with adjuvant	Other	trivalent human seasonal influenza vaccine (TIV)	protein-nanoparticle vaccine	Prime-boost vaccine with DNA vaccine priming	Total
G- bacterium	22/51	2	6	97	11	7	2	6	0	0	0	0	0	0	131
G+ bacterium	11/17	2	26	39	17	6	4	1	0	1	0	0	0	0	96
parasite	15/25	6	0	53	0	0	1	4	1	0	0	0	1	2	68
Allergy	1/1	0	0	1	0	0	0	0	0	0	0	0	0	0	1
Cancer	1/1	7	0	12	0	1	0	8	1	0	4	0	0	0	33
Atherosclerosis	1/1	0	0	2	0	0	0	0	0	0	0	0	0	0	2
virus	28/115	2	0	44	11	0	23	1	3	0	0	1	0	0	85
fungus	1/1	0	0	3	0	0	0	0	0	0	0	0	0	0	3
Total	80/212	19	32	251	39	14	30	20	5	1	4	1	1	2	419

Click here for the list of vaccines that use two or more adjuvants.