VIOLIN: Vaccine Investigation and Online Information Network

Vaxjo: Vaccine Adjuvants

Currently, Vaxjo includes 94 vaccine adjuvants. The detailed curated data is shown below:

Index	Vaccine Adjuvant Name	No. of associated vaccines
1	Abisco-100 vaccine adjuvant	1
2	Adamantylamide Dipeptide Vaccine Adjuvant	1
3	Adjumer™	1
4	AF03	1
5	Algammulin	1
6	Alhydrogel	13
7	Alhydroxiquim-II	1
8	aluminum hydroxide vaccine adjuvant	62
9	aluminum phosphate vaccine adjuvant	50
10	aluminum potassium sulfate adjuvant	6
11	Aluminum vaccine adjuvant	14
12	amorphous aluminum hydroxyphosphate sulfate adjuvant	2
13	Arlacel A	1
14	AS-2 vaccine adjuvant	1
15	AS02	4
16	AS03	2
17	AS04	1
18	Avridine®	1
19	B7-2 vaccine adjuvant	1
20	Bay R1005	1
21	Bordetella pertussis component Vaccine Adjuvant	3
22	Calcium phosphate vaccine adjuvant	1
23	Cationic Liposomal Vaccine Adjuvant	2
24	Cationic liposome-DNA complex JVRS-100	1
25	Cholera toxin	17
26	Cholera toxin B subunit	6
27	Corynebacterium-derived P40 Vaccine Adjuvant	1
28	CpG DNA Vaccine Adjuvant	13
29	CRL1005	2
30	CTA1-DD gene fusion protein	2
31	DDA Adjuvant	3
32	DHEA vaccine adjuvant	1
33	DL-PGL (Polyester poly (DL-lactide-co-glycolide)) vaccine adjuvant	1
34	DOC/Alum Complex	1
35	E. coli heat-labile toxin, LT	3
36	Etx B subunit Adjuvant	2
37	Flagellin	1
38	Freund's Complete Adjuvant	42
39	Freund's Incomplete Adjuvant	43
40	Gamma Inulin	1
41	Gerbu Adjuvant	1
42	GM-CSF	24
43	GMDP	1
44	IL-12 Vaccine Adjuvant	9
45	IL-15 vaccine adjuvant	1
46	Imiquimod	1
47	Immunoliposomes Containing Antibodies to Costimulatory Molecules	1
48	Interleukin-1β	1
49	Interleukin-2	1
50	Interleukin-7	1
51	ISCOM(s)™	2
52	ISCOMATRIX®	1
53	Killed Corynebacterium parvum Vaccine Adjuvant	2
54	Lipopolysaccharide Vaccine Adjuvant	1
55	Liposomes	2
56	Loxoribine	1
57	LTK63 Vaccine Mutant Adjuvant	2
58	LTK72 vaccine adjuvant	1
59	LTR192G Vaccine Adjuvant	6
60	Matrix-S	1
61	MF59	5
62	Montanide Incomplete Seppic Adjuvant	1
63	Montanide ISA 51	1
64	Montanide ISA 720 Adjuvant	6
65	MPL-SE vaccine adjuvant	1
66	MPL™ Adjuvant	9
67	MTP-PE Liposomes	2
68	Muramyl Dipeptide Adjuvant	1
69	NAGO	1
70	nanoemulsion vaccine adjuvant	3
71	Non-Ionic Surfactant Vesicles	1
72	non-toxic mutant E112K of Cholera Toxin mCT-E112K	1
73	PMMA	1
74	Poly(I:C)	1
75	Polygen Vaccine Adjuvant	1
76	Protein Cochleates	1
77	QS-21	1
78	Quil-A vaccine adjuvant	5
79	RC529 vaccine adjuvant	1
80	Recombinant hIFN-gamma/Interferon-g	1
81	Rehydragel HPA	1
82	Rehydragel LV	1
83	Ribi Vaccine Adjuvant	11
84	SAF-1	1
85	Saponin Vaccine Adjuvant	4
86	Specol	1
87	SPT (Antigen Formulation)	1
88	Squalene-based Adjuvants	1
89	Stearyl Tyrosine	1
90	Theramide®	1
91	Threonyl muramyl dipeptide (TMDP)	1
92	TiterMax Gold Adjuvant	3
93	Ty Particles vaccine adjuvant	1
94	VSA-3 Adjuvant	2
Total		404 (unique ones)

Vaccines with adjuvants by vaccine targeted pathogens or diseases

Pathogen or disease	No. of pathogen species	Subunit vaccine	Toxoid vaccine	Subunit vaccine + Inactivated or "killed" vaccine	Conjugate vaccine	Inactivated or "killed" vaccine	DNA vaccine	Recombinant vector vaccine	Live, attenuated vaccine	Other	Fusion protein with adjuvant	Total
virus	27/115	43	0	12	0	21	2	1	2	0	0	81
G- bacterium	22/50	97	6	11	7	2	2	6	0	0	0	131
parasite	15/25	50	0	0	0	1	1	2	1	0	0	55
G+ bacterium	11/17	39	26	17	6	4	2	1	0	0	1	96
Allergy	1/1	1	0	0	0	0	0	0	0	0	0	1
Cancer	1/1	12	0	0	1	0	7	8	1	6	0	35
Atherosclerosis	1/1	2	0	0	0	0	0	0	0	0	0	2
fungus	1/1	3	0	0	0	0	0	0	0	0	0	3
Total	79/211	247	32	40	14	28	14	18	4	6	1	404

Click here for the list of vaccines that use two or more adjuvants.