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GLA-Alum |
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Vaxjo ID |
161 |
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Vaccine Adjuvant Name |
GLA-Alum |
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Adjuvant VO ID |
VO_0006099
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Description |
A combination vaccine adjuvant of a synthetic TLR agonist and aluminum salt that induces a Th1 response |
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Stage of Development |
Clinical Trial |
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Location Licensed |
US (AAHI) |
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Host Species for Testing |
2 |
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Second Host Species for Testing |
3 |
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Components |
Aluminum hydroxide with TLR-4 agonist (GLA) and dipalmitoyl phosphatidylcholine |
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Storage |
2-8C |
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Function |
innate immune activation |
| References |
(Soza, 2024): Vaccine Adjuvant Compendium - VAC [https://vac.niaid.nih.gov/view?id=83]
Tamborrini et al., 2023: Tamborrini M, Schäfer A, Hauser J, Zou L, Paris DH, Pluschke G. The malaria blood stage antigen PfCyRPA formulated with the TLR-4 agonist adjuvant GLA-SE elicits parasite growth inhibitory antibodies in experimental animals. Malaria journal. 2023; 22(1); 210. [PubMed: 37454145].
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