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Precision Vaccines Program (PVP)-037

Vaxjo ID 186       
Vaccine Adjuvant Name Precision Vaccines Program (PVP)-037       
Adjuvant VO ID VO_0005382
Description small molecule Imidazopyrimidine TLR7 agonist that induces Th1 response       
Stage of Development Research       
Location Licensed US (Boston Children's Hospital)       
Host Species for Testing Mouse       
Second Host Species for Testing Pig       
Components Imidazopyrimidine       
Storage Lyophilized pharmacophore and API formulations stable at 4C or colder (months to years), Lyophilized pharmacophore and API formulations stable at -20C/-80C for long-term storage       
Function innate immune activation       
References
(Levy, 2023): Vaccine Adjuvant Compendium - VAC [https://vac.niaid.nih.gov/view?id=56]