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Precision Vaccines Program (PVP)-037

Vaxjo ID 186
Vaccine Adjuvant Name Precision Vaccines Program (PVP)-037
Adjuvant VO ID VO_0005382
Description small molecule Imidazopyrimidine TLR7 agonist that induces Th1 response
Stage of Development Research
Location Licensed US (Boston Children's Hospital)
Host Species for Testing 3
Second Host Species for Testing 15
Components Imidazopyrimidine
Storage Lyophilized pharmacophore and API formulations stable at 4C or colder (months to years), Lyophilized pharmacophore and API formulations stable at -20C/-80C for long-term storage
Function innate immune activation
References
(Levy, 2023): Vaccine Adjuvant Compendium - VAC [https://vac.niaid.nih.gov/view?id=56]