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UM-1098 |
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Vaxjo ID |
202 |
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Vaccine Adjuvant Name |
UM-1098 |
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Adjuvant VO ID |
VO_0005282
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Description |
Small molecule with CLR (Dectin, Mincle) receptor that induces Th17 reponse |
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Stage of Development |
Research |
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Location Licensed |
US (U. Montana & Inimmune) |
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Host Species for Testing |
Mouse |
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Storage |
room temp |
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Function |
Type: particulate antigen delivery system vaccine adjuvant. Target Receptor: C-type lectin domain family 4 member E (Mincle).. Induces Th17-biased immune profile. |
| References |
(Ryter, 2024): Vaccine Adjuvant Compendium - VAC [https://vac.niaid.nih.gov/view?id=27]
Abdelwahab et al., 2024: Abdelwahab WM, Le-Vinh B, Riffey A, Hicks L, Buhl C, Ettenger G, Jackson KJ, Weiss AM, Miller S, Ryter K, Evans JT, Burkhart DJ. Promotion of Th17 Polarized Immunity via Co-Delivery of Mincle Agonist and Tuberculosis Antigen Using Silica Nanoparticles. ACS applied bio materials. 2024; 7(6); 3877-3889. [PubMed: 38832760].
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