|
|
Babassu aqueous extract |
|
Vaxjo ID |
361 |
|
Vaccine Adjuvant Name |
Babassu aqueous extract |
|
Adjuvant VO ID |
VO_0005555
|
|
Description |
natural adjuvant that induces a Th1 response |
|
Stage of Development |
Research |
|
Host Species for Testing |
3 |
|
Components |
babassu aqueous extract, polysaccharides, 94.5%; proteins, 2.2%; lipids, 0.5%; monosaccharides and disaccharides, 1.8%; amino acids, < 1.0% |
|
Preparation |
Eighty grams of the mesocarp flour were extracted during 1 h with 1 L of sterilized water, at 24°C, under constant stirring, then filtered and diluted in PBS to appropriate concentrations |
|
Function |
Increased IFN-γ production |
| References |
Guerra et al., 2011: Guerra RN, Silva VM, Aragão-França LS, Oliveira PR, Feitosa R, Nascimento FR, Pontes-de-Carvalho LC. Babassu aqueous extract (BAE) as an adjuvant for T helper (Th)1-dependent immune responses in mice of a Th2 immune response-prone strain. BMC immunology. 2011; 12; 13. [PubMed: 21276258].
|
|
