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Babassu aqueous extract |
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Vaxjo ID |
361 |
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Vaccine Adjuvant Name |
Babassu aqueous extract |
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Adjuvant VO ID |
VO_0005535
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Description |
natural adjuvant that induces a Th1 response |
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Stage of Development |
Research |
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Host Species for Testing |
Mouse |
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Components |
babassu aqueous extract, polysaccharides, 94.5%; proteins, 2.2%; lipids, 0.5%; monosaccharides and disaccharides, 1.8%; amino acids, < 1.0% |
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Preparation |
Eighty grams of the mesocarp flour were extracted during 1 h with 1 L of sterilized water, at 24°C, under constant stirring, then filtered and diluted in PBS to appropriate concentrations |
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Function |
Increased IFN-γ production |
| References |
Guerra et al., 2011: Guerra RN, Silva VM, Aragão-França LS, Oliveira PR, Feitosa R, Nascimento FR, Pontes-de-Carvalho LC. Babassu aqueous extract (BAE) as an adjuvant for T helper (Th)1-dependent immune responses in mice of a Th2 immune response-prone strain. BMC immunology. 2011; 12; 13. [PubMed: 21276258].
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