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B7-2 vaccine adjuvant |
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Vaxjo ID |
92 |
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Vaccine Adjuvant Name |
B7-2 vaccine adjuvant |
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Alternative Names |
CD86 |
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Adjuvant VO ID |
VO_0001337
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Description |
The gene product encoded by B7-2 is a co-stimulatory molecule for GM-CSF. The genes had been cloned by PCR from baboon peripheral blood mononuclear cells (PBMC) and were sequenced, then sub-cloned into the mammalian expression vector, pND-14. |
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Stage of Development |
Research |
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Function |
B7-2 activates a Th2 response (Marciani, 2003). |
| Related Vaccine(s) |
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| References |
Marciani, 2003: Marciani DJ. Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity. Drug discovery today. 2003; 8(20); 934-943. [PubMed: 14554157].
Wiki: CD86: Wiki: CD86 [http://en.wikipedia.org/wiki/CD86]
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