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Stearyl Tyrosine |
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Vaxjo ID |
43 |
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Vaccine Adjuvant Name |
Stearyl Tyrosine |
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Adjuvant VO ID |
VO_0001316
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Description |
Primary vaccine adjuvant with minimal immunostimulatory properties. Some use in allergy desensitization therapy (Vogel and Powell, 1995). |
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Stage of Development |
Research |
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Components |
Octadecyl tyrosine hydrocholoride (stearyl tyrosine)(Vogel and Powell, 1995). |
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Function |
Stearyl Tyrosine is considered an "organic equivelant" of aluminum hydroxide, with adjuvanticity similar to aluminum hydroxide in bacterial vaccines, superior to aluminum hydroxide in viral vaccines (Vogel and Powell, 1995). |
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Safety |
Non-toxic up to 2500 mg/kg in many animals, including primates. Nonpyrogenic, no adjuvant arthritis in rats, and no damage at the site of injection in cats (Vogel and Powell, 1995). |
| Related Vaccine(s) |
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| References |
Vogel and Powell, 1995: Vogel FR, Powell MF. A compendium of vaccine adjuvants and excipients. Pharmaceutical biotechnology. 1995; 6; 141-228. [PubMed: 7551218].
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