Propionibacterium acnes(P. acnes) |
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Vaxjo ID |
347 |
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Vaccine Adjuvant Name |
Propionibacterium acnes(P. acnes) |
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Adjuvant VO ID |
VO_0005270
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|
Description |
Propionibacterium acnes is a bacterium that acts as an adjuvant to enhance the immunogenicity of the HIVBr18 human immunodeficiency virus-1 vaccine. |
|
Stage of Development |
Research |
|
Host Species for Testing |
Mouse |
|
Structure |
Whole bacterium; a soluble polysaccharide extracted from the P. acnes cell wall. |
|
Function |
P. acnes was found to be a potent adjuvant capable of potentiating the effects of the HIVBr18 vaccine. Therefore, P. acnes may be a potential adjuvant to aid this vaccine in inducing immunity or for therapeutic use. |
| Related Vaccine(s) |
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| References |
Teixeira et al., 2018: Teixeira D, Ishimura ME, Apostólico JS, Viel JM, Passarelli VC, Cunha-Neto E, Rosa DS, Longo-Maugéri IM. Propionibacterium acnes Enhances the Immunogenicity of HIVBr18 Human Immunodeficiency Virus-1 Vaccine. Frontiers in immunology. 2018; 9; 177. [PubMed: 29467764].
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