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CCL19 |
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Vaxjo ID |
339 |
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Vaccine Adjuvant Name |
CCL19 |
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Adjuvant VO ID |
VO_0005582
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Description |
chemokine adjuvant that prodices a mixed Th1/Th2 response |
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Stage of Development |
Research |
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Host Species for Testing |
Mouse |
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Components |
CCR7-ligands CCL19 |
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Preparation |
DNAs were coated onto 0.8–1.5 μm gold particles following a protocol developed for the helium-driven gene delivery systems from Bio-Rad |
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Function |
CD8⁺ T cell activation |
| References |
Nguyen-Hoai et al., 2012: Nguyen-Hoai T, Hohn O, Vu MD, Baldenhofer G, Sayed Ahmed MS, Dörken B, Norley S, Lipp M, Pezzutto A, Westermann J. CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: improved vaccine efficacy and a role for B cells as APC. Cancer gene therapy. 2012; 19(12); 880-887. [PubMed: 23099886].
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