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CS3 adjuvant |
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Vaxjo ID |
375 |
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Vaccine Adjuvant Name |
CS3 adjuvant |
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Adjuvant VO ID |
VO_0005534
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Description |
natural polysaccharide adjuvant that induces a mixed Th1/Th17 response |
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Stage of Development |
Research |
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Host Species for Testing |
Mouse |
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Components |
curdlan sulfate |
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Preparation |
dissolved in DMSO, added 2.5 g of sulfur trioxide–pyridine complex and heated at 65C and cooled, precipitated, dissolved, and filtered out |
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Function |
enhances DC activation and CD4+ cells |
| References |
Byrd and Cassels, 2006: Byrd W, Cassels FJ. The encapsulation of enterotoxigenic Escherichia coli colonization factor CS3 in biodegradable microspheres enhances the murine antibody response following intranasal administration. Microbiology (Reading, England). 2006; 152(Pt 3); 779-786. [PubMed: 16514157].
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