BECC470s |
|
Vaxjo ID |
148 |
|
Vaccine Adjuvant Name |
BECC470s |
|
Adjuvant VO ID |
VO_0005383
|
|
Description |
synthetic derivative of natural compound with TLR4 receptor that induces TH1/2/17 response |
|
Stage of Development |
Research |
|
Location Licensed |
US (University of Maryland, Baltimore) |
|
Host Species for Testing |
Mouse |
|
Second Host Species for Testing |
Rabbit |
|
Preparation |
Formulated as an emulsion (AS03 biosimilar) - stable for 2 weeks at 40ºC using an Influenza immunization and challenge model. Longer stability studies were not carried. |
|
Function |
Induces mucosal immunity, induces epitope spreading |
| References |
VAC-60: BECC470s: [https://vac.niaid.nih.gov/view?id=60]
|