Abisco-100 vaccine adjuvant |
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Vaxjo ID |
89 |
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Vaccine Adjuvant Name |
Abisco-100 vaccine adjuvant |
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Adjuvant VO ID |
VO_0001334
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Description |
AbISCO®-100 is a saponin based adjuvant that has been proven to be non-toxic and possess dose sparing potentials (AbISCO-100 Website). |
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Stage of Development |
Research |
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Storage |
The products are stable at least 2 years at +2 to +8 °C. Shorter periods (5-10 days) of exposure to ambient temperatures < 40 °C, e.g., during shipping, have no negative effects on the preparation. If the antigen is sterile and free of proteolytic enzymes, antigen-adjuvant mixtures can be stored at +2 to +8 °C for months provided that the antigen stability at dilution is adequate (AbISCO-100 Website). |
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Preparation |
AbISCO®-100 is made from highly purified saponins selected for consistent potent adjuvant activity for a variety of antigens in mice while also minimizing the risks for side-effects.
The preparation can without compromising with efficacy be used in other animal species, especially in cases where particularly high doses of adjuvant will be used, when very young individuals will be immunized, or if the animal species in question has been reported as more sensitive than others to quillaja saponins (AbISCO-100 Website). |
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Function |
The AbISCO®-100 adjuvant is one of Isconova’s research reagents suitable for studies on e.g. humoral and cell mediated immune responses. This adjuvant can be used in different phases of scientific and product oriented research and development. AbISCO®-100 generates immune responses of both Th1 and Th2 type, induce broad antibody responses including several classes and subclasses, as well as potent CTL responses (AbISCO-100 Website). |
| Related Vaccine(s) |
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| References |
AbISCO-100 Website: AbISCO®-100 [http://www.isconova.com/products/abisco-research-reagent/abisco-100.aspx]
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