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Vaccine Detail

B16 Vaccine adjuvanted by Loxoribine

Vaccine Information

Vaccine Name: B16 Vaccine adjuvanted by Loxoribine
Vaccine Ontology ID: VO_0001380
Type: Live, attenuated vaccine
Status: Research
Antigen: Irradiated B16 cells (Pope et al., 1994).
Adjuvant: Loxoribine vaccine adjuvant
- VO ID: VO_0001300
Preparation: Loxoribine can be used to promote inhibition of B16 metastasis (Pope et al., 1994).
Immunization Route: Intraperitoneal injection (i.p.)
Description: This vaccine has been used in clinical trials involving melanoma. (Pope et al., 1994)

References

Pope et al., 1994: Pope BL, Sigindere J, Chourmouzis E, MacIntyre P, Goodman MG. 7-Allyl-8-oxoguanosine (loxoribine) inhibits the metastasis of B16 melanoma cells and has adjuvant activity in mice immunized with a B16 tumor vaccine. Cancer immunology, immunotherapy : CII. 1994; 38(2); 83-91. [PubMed: 8306370].