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NP DNA adjuvant |
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Vaxjo ID |
370 |
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Vaccine Adjuvant Name |
NP DNA adjuvant |
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Adjuvant VO ID |
VO_0005662
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Description |
novel genetic adjuvant that induces Th1 response |
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Stage of Development |
Research |
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Host Species for Testing |
Mouse |
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Components |
influenza virus nucleoprotein (NP) |
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Preparation |
gene was cleaved by XhoI/XbaI and KpnI/Xho I, were inserted into pTV2 vector to prepare pTV-NP |
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Function |
augments in vivo proliferation of adoptively transferred antigen-specific CD4 and CD8 T cells |
| References |
Choi et al., 2009: Choi SY, Suh YS, Cho JH, Jin HT, Chang J, Sung YC. Enhancement of DNA Vaccine-induced Immune Responses by Influenza Virus NP Gene. Immune network. 2009; 9(5); 169-178. [PubMed: 20157605].
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