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3M-052-SE |
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Vaxjo ID |
142 |
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Vaccine Adjuvant Name |
3M-052-SE |
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Adjuvant VO ID |
VO_0005386
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Description |
synthetic derivative of natural compound with TLR7 and TLR8 receptors, emulsion, compound adjuvant |
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Stage of Development |
Research |
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Location Licensed |
United States |
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Host Species for Testing |
Mouse |
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Components |
3M-052 |
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Storage |
2-8C |
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Preparation |
squalene based oil in water emulsion |
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Function |
Type: TLR agonist vaccine adjuvant. Toll-like receptor 7 (TLR7) | Toll-like receptor 8 (TLR8). Induces Th1-biased immune profile. innate immune activation |
| References |
(Soza, 2025): Vaccine Adjuvant Compendium - VAC [https://vac.niaid.nih.gov/view?id=57]
Phillips et al., 2018: Phillips B, Van Rompay KKA, Rodriguez-Nieves J, Lorin C, Koutsoukos M, Tomai M, Fox CB, Eudailey J, Dennis M, Alam SM, Hudgens M, Fouda G, Pollara J, Moody A, Shen X, Ferrari G, Permar S, De Paris K. Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques. Journal of virology. 2018; 92(20); . [PubMed: 30089691].
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