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IL-36 |
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Vaxjo ID |
341 |
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Vaccine Adjuvant Name |
IL-36 |
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Adjuvant VO ID |
VO_0005632
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Description |
genetic adjuvant that induces a Th1 response |
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Stage of Development |
Research |
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Host Species for Testing |
Mouse |
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Components |
Murine IL-36Ra, IL-36α, IL-36β, IL-36γ were produced at Amgen Inc as N-terminal truncation variants |
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Function |
activated naive CD4+ T production |
| References |
Vigne et al., 2012: Vigne S, Palmer G, Martin P, Lamacchia C, Strebel D, Rodriguez E, Olleros ML, Vesin D, Garcia I, Ronchi F, Sallusto F, Sims JE, Gabay C. IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells. Blood. 2012; 120(17); 3478-3487. [PubMed: 22968459].
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