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Vaccine Detail

Phleum pratense Allergy Phl p 12 Subunit Vaccine

Vaccine Information

Vaccine Name: Phleum pratense Allergy Phl p 12 Subunit Vaccine
Vaccine Ontology ID: VO_0011374
Type: Subunit vaccine
Status: Research
Antigen: A recombinant protein comprised of the C terminus of Phl p 12 at its N terminus and the Phl p 12 N terminus at its C terminus, Phl p 12-rs, was expressed in Escherichia coli and purified (Westritschnig et al., 2007).
PRO2 gene engineering:
- Type: Recombinant protein preparation
- Detailed Gene Information: Click Here.
Adjuvant:
- VO ID: VO_0000127
Immunization Route: subcutaneous injection

References

Westritschnig et al., 2007: Westritschnig K, Linhart B, Focke-Tejkl M, Pavkov T, Keller W, Ball T, Mari A, Hartl A, Stöcklinger A, Scheiblhofer S, Thalhamer J, Ferreira F, Vieths S, Vogel L, Böhm A, Valent P, Valenta R. A hypoallergenic vaccine obtained by tail-to-head restructuring of timothy grass pollen profilin, Phl p 12, for the treatment of cross-sensitization to profilin. Journal of immunology (Baltimore, Md. : 1950). 2007; 179(11); 7624-7634. [PubMed: 18025208].