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BI-Eng2 |
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Vaxjo ID |
149 |
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Vaccine Adjuvant Name |
BI-Eng2 |
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Adjuvant VO ID |
VO_0005507
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Description |
Vaccine adjuvant with CLR(dectin, mincle) that is primarily composed of protein and actives innate immune pathways to induce a mixed Th1/Th2 response |
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Stage of Development |
Research |
|
Location Licensed |
US (University of Wisconsin) |
|
Host Species for Testing |
3 |
|
Second Host Species for Testing |
6 |
|
Components |
glycoprotein |
|
Function |
induces the production of IL-1β and IL-6 by dendritic cells and acts as an adjuvant to promote differentiation of CD4+ T cells into anti-fungal Th17 cells |
| References |
VAC-97: Bl-Eng2: [https://vac.niaid.nih.gov/view?id=97]
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