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iron oxide nanoparticles |
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Vaxjo ID |
348 |
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Vaccine Adjuvant Name |
iron oxide nanoparticles |
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Adjuvant VO ID |
VO_0005270
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Description |
A novel combined use of iron oxide nanoparticles (superparamagnetic Fe3O4 nanoparticles) serving as both a vaccine delivery platform and an immune potentiator. It is designed to enhance both humoral and cellular immune responses for cancer treatment. |
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Stage of Development |
Research |
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Host Species for Testing |
Mouse |
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Structure |
Superparamagnetic Fe3O4 nanoparticles |
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Function |
Our iron oxide nanoparticles greatly promoted the activation of immune cells and cytokine production, inducing potent humoral and cellular immune responses. |
| Related Vaccine(s) |
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| References |
Zhao et al., 2018: Zhao Y, Zhao X, Cheng Y, Guo X, Yuan W. Iron Oxide Nanoparticles-Based Vaccine Delivery for Cancer Treatment. Molecular pharmaceutics. 2018; 15(5); 1791-1799. [PubMed: 29570298].
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