|
|
iron oxide nanoparticles |
|
Vaxjo ID |
348 |
|
Vaccine Adjuvant Name |
iron oxide nanoparticles |
|
Adjuvant VO ID |
VO_0005638
|
|
Description |
A novel combined use of iron oxide nanoparticles (superparamagnetic Fe3O4 nanoparticles) serving as both a vaccine delivery platform and an immune potentiator. It is designed to enhance both humoral and cellular immune responses for cancer treatment. |
|
Stage of Development |
Research |
|
Host Species for Testing |
Mouse |
|
Structure |
Superparamagnetic Fe3O4 nanoparticles |
|
Function |
Our iron oxide nanoparticles greatly promoted the activation of immune cells and cytokine production, inducing potent humoral and cellular immune responses. |
| References |
Zhao et al., 2018: Zhao Y, Zhao X, Cheng Y, Guo X, Yuan W. Iron Oxide Nanoparticles-Based Vaccine Delivery for Cancer Treatment. Molecular pharmaceutics. 2018; 15(5); 1791-1799. [PubMed: 29570298].
|
|
