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Vaxvec: Vaccine Vectors

Currently, Vaxvec includes 60 vaccine vectors each of which has been used in at least one recombinant vector vaccine. The detailed curated data is shown below:

Index ASC Vaccine Vector Name No. of associated vaccines
1 Actinobacillus pleuropneumoniae vaccine vector 2
2 adeno-associated virus vector 2
3 Adenoviral vector 3
4 Adenovirus serotype 5 vaccine vector 1
5 ALVAC vaccine vector 17
6 Attenuated Listeria monocytogenes vaccine vector 1
7 avian paramyxovirus type 3 vaccine vector 1
8 Baculovirus vaccine vector 7
9 BCG vaccine vector 9
10 Bordetella pertussis BPZE vaccine vector 2
11 bovine herpesvirus 4 (BoHV-4) vaccine vector 2
12 bovine parainfluenza virus vaccine vector 1
13 Brucella abortus RB51 vaccine vector 2
14 canarypox viral vector 4
15 capripoxvirus vaccine vector 1
16 chimpanzee adenovirus vaccine vector 1
17 complex adenovirus vaccine vector 7
18 Corynebacterium pseudotuberculosis vaccine vector 1
19 Coxsackievirus vaccine vector 2
20 Cytomegalovirus vaccine vector 3
21 duck enteritis virus vector 2
22 E. coli vaccine vector 1
23 Edwardsiella tarda EIB202 vaccine vector 2
24 Fowlpox virus vaccine vector 15
25 Herpes simplex virus 1 vaccine vector 1
26 herpesvirus of turkey vector 6
27 Human adenoviral vectors 2
28 Lactobacillus gasseri vaccine vector 1
29 Leishmania tarentolae vaccine vector 3
30 Lentiviral vaccine vector 2
31 Listeria monocytogenes LM1-2 vaccine vector 1
32 Lumpy Skin Disease Virus (LSDV) 2
33 Maraba Virus vaccine vector 2
34 measles virus vaccine vector 4
35 MVA virus vaccine vector 7
36 Mycobacterium smegmatis vaccine vector 2
37 myxoma virus vaccine vector 2
38 Newcastle disease virus vaccine vector 4
39 NYVAC vaccine vector 9
40 Oka varicella vaccine vector 2
41 ORF virus vaccine vector 6
42 poliovirus vaccine vector 2
43 porcine adenovirus 3 vaccine vector 3
44 pseudorabies virus (PrV) vaccine vector 3
45 PVSRIPO vaccine vector 1
46 Raccoon poxvirus vaccine vector 4
47 Retroviral vaccine vector 1
48 Rous sarcoma virus vaccine vector 2
49 Saccharomyces cerevisiae vaccine vector 2
50 Salmonella enterica SL3261 vaccine vector 6
51 Salmonella typhi vaccine vector 3
52 simian adenovirus ChAd63 vaccine vector 2
53 Streptococcus gordonii vaccine vector 3
54 swinepox virus vector 3
55 vaccinia virus TianTan (MVTT) 4
56 Vaccinia virus vector 1
57 Venezuelan equine encephalitis virus vaccine vector 2
58 Vesicular stomatitis virus vaccine vector 5
59 Vibrio cholerae vaccine vector 4
60 yellow fever vaccine virus 17D vaccine vector 1
Total 197 (unique ones)
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Vaccines with vectors by vaccine targeted pathogens or diseases

Pathogen No. of pathogen species Recombinant vector vaccine
virus 40/115 136
parasite 8/25 18
G- bacterium 11/51 22
G+ bacterium 6/17 11
Total 66/209 187

 

Many recombinant vaccine vectors have also been used for development of recombinant vector cancer vaccines.