VIOLIN: Vaccine Investigation and Online Information Network

Vaxvec: Vaccine Vectors

Currently, Vaxvec includes 60 vaccine vectors each of which has been used in at least one recombinant vector vaccine. The detailed curated data is shown below:

Index	Vaccine Vector Name	No. of associated vaccines
1	Actinobacillus pleuropneumoniae vaccine vector	2
2	adeno-associated virus vector	2
3	Adenoviral vector	3
4	Adenovirus serotype 5 vaccine vector	1
5	ALVAC vaccine vector	17
6	Attenuated Listeria monocytogenes vaccine vector	1
7	avian paramyxovirus type 3 vaccine vector	1
8	Baculovirus vaccine vector	7
9	BCG vaccine vector	9
10	Bordetella pertussis BPZE vaccine vector	2
11	bovine herpesvirus 4 (BoHV-4) vaccine vector	2
12	bovine parainfluenza virus vaccine vector	1
13	Brucella abortus RB51 vaccine vector	2
14	canarypox viral vector	4
15	capripoxvirus vaccine vector	1
16	chimpanzee adenovirus vaccine vector	1
17	complex adenovirus vaccine vector	7
18	Corynebacterium pseudotuberculosis vaccine vector	1
19	Coxsackievirus vaccine vector	2
20	Cytomegalovirus vaccine vector	3
21	duck enteritis virus vector	2
22	E. coli vaccine vector	1
23	Edwardsiella tarda EIB202 vaccine vector	2
24	Fowlpox virus vaccine vector	15
25	Herpes simplex virus 1 vaccine vector	1
26	herpesvirus of turkey vector	6
27	Human adenoviral vectors	2
28	Lactobacillus gasseri vaccine vector	1
29	Leishmania tarentolae vaccine vector	3
30	Lentiviral vaccine vector	2
31	Listeria monocytogenes LM1-2 vaccine vector	1
32	Lumpy Skin Disease Virus (LSDV)	2
33	Maraba Virus vaccine vector	2
34	measles virus vaccine vector	4
35	MVA virus vaccine vector	7
36	Mycobacterium smegmatis vaccine vector	2
37	myxoma virus vaccine vector	2
38	Newcastle disease virus vaccine vector	4
39	NYVAC vaccine vector	9
40	Oka varicella vaccine vector	2
41	ORF virus vaccine vector	6
42	poliovirus vaccine vector	2
43	porcine adenovirus 3 vaccine vector	3
44	pseudorabies virus (PrV) vaccine vector	3
45	PVSRIPO vaccine vector	1
46	Raccoon poxvirus vaccine vector	4
47	Retroviral vaccine vector	1
48	Rous sarcoma virus vaccine vector	2
49	Saccharomyces cerevisiae vaccine vector	2
50	Salmonella enterica SL3261 vaccine vector	6
51	Salmonella typhi vaccine vector	3
52	simian adenovirus ChAd63 vaccine vector	2
53	Streptococcus gordonii vaccine vector	3
54	swinepox virus vector	3
55	vaccinia virus TianTan (MVTT)	4
56	Vaccinia virus vector	1
57	Venezuelan equine encephalitis virus vaccine vector	2
58	Vesicular stomatitis virus vaccine vector	5
59	Vibrio cholerae vaccine vector	4
60	yellow fever vaccine virus 17D vaccine vector	1
Total		197 (unique ones)

-----------

Vaccines with vectors by vaccine targeted pathogens or diseases

Pathogen	No. of pathogen species	Recombinant vector vaccine
virus	40/115	136
parasite	8/25	18
G- bacterium	11/51	22
G+ bacterium	6/17	11
Total	66/209	187

Many recombinant vaccine vectors have also been used for development of recombinant vector cancer vaccines.