Gene ID |
Gene Name |
Sequence Strain (Species/Organism) |
VO ID |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
3D structure: PDB ID |
Other Database IDs |
Protein Name |
Molecule Role |
Vaccines Involving this Gene |
4107
|
emm |
Streptococcus pyogenes |
|
|
|
AAN04081
|
|
|
|
|
CDD:235600 CDD:274008 |
M24 |
Protective antigen |
|
854
|
emm1 |
Streptococcus pyogenes |
VO_0012397
|
|
311757
|
311758
|
|
|
CAA44062.1 |
2OTO
|
CDD:273479 CDD:291694 CDD:295219 CDD:279132 GOA:Q10372 HSSP: 1IC2 InterPro: IPR001899 InterPro: IPR005877 InterPro: IPR019931 InterPro: IPR019948 InterPro: IPR019950 UniProtKB/TrEMBL: Q10372 |
M protein type 1 |
Protective antigen |
S. pyogenes M Protein Vaccine
|
4112
|
emm12 mutant |
Streptococcus pyogenes |
|
|
|
BAD14986
|
|
|
|
|
ATCC:12353 CDD:273479 CDD:302792 CDD:303051 CDD:287450 CDD:295219 |
M12 mutant protein precursor |
Protective antigen |
|
4115
|
emm3 |
Streptococcus pyogenes |
|
|
|
CAA56449
|
|
|
|
|
CDD:273479 CDD:303051 CDD:287450 CDD:287215 CDD:279132 GOA:Q54835 InterPro: IPR001899 InterPro: IPR005877 InterPro: IPR019931 InterPro: IPR019948 InterPro: IPR019950 UniProtKB/TrEMBL: Q54835 |
M3 protein |
Protective antigen |
|
853
|
fbaA |
Streptococcus pyogenes SSI-9 |
VO_0012396
|
|
|
14915682
|
|
|
|
|
CDD:273479 CDD:320995 CDD:273478 |
fibronectin-binding protein |
Protective antigen |
S. pyogenes FbaA Protein Vaccine
|
4127
|
fbaA |
Streptococcus pyogenes |
|
|
|
AMY98237
|
|
|
|
|
CDD:273479 CDD:331285 CDD:273478 |
Fibronectin-binding protein |
Protective antigen |
|
4152
|
fbp54 |
Streptococcus pyogenes |
|
|
|
AAR18990
|
|
|
|
|
CDD:224212 CDD:283353 |
fibronectin/fibrinogen-binding protein |
Protective antigen |
S. pyogenes FBP54 Protein Vaccine
|
4151
|
hypothetical protein MGAS2096_Spy1592 |
Streptococcus pyogenes M1 GAS |
|
|
|
ABF36644
|
|
|
|
|
|
hypothetical protein |
Protective antigen |
|
4138
|
hypothetical protein SPy_0130 |
Streptococcus pyogenes |
|
|
|
NP_268519
|
|
|
|
|
CDD:274781 |
hypothetical protein |
Protective antigen |
|
4142
|
hypothetical protein SPy_0843 |
Streptococcus pyogenes M1 GAS |
|
|
|
NP_269051
|
|
|
|
|
CDD:315882; CDD:275383 |
hypothetical protein |
Protective antigen |
|
4135
|
inlA |
Streptococcus pyogenes M1 GAS |
|
|
|
NP_269467
|
|
|
|
|
CDD:331999 CDD:275380 CDD:227223 |
putative internalin A precursor |
Protective antigen |
|
4119
|
isp2 |
Streptococcus pyogenes |
|
|
|
NP_269810
|
|
|
|
|
CDD:330579 CDD:226451 |
immunogenic secreted precursor-like protein |
Protective antigen |
|
4105
|
M1 |
Streptococcus pyogenes |
|
|
|
AAA85117
|
|
|
|
|
CDD:236892 |
M1 protein |
Protective antigen |
|
4111
|
M14 |
Streptococcus pyogenes |
|
|
|
PHP24645
|
|
|
|
|
|
peptidase M14 |
Protective antigen |
|
4116
|
M18 |
Streptococcus pyogenes |
|
|
|
WP_011018277
|
|
|
|
|
CDD:291694 CDD:295219 CDD:279132 |
LPXTG cell wall anchor domain-containing protein |
Protective antigen |
|
4117
|
M22 |
Streptococcus pyogenes |
|
|
|
AKI36048
|
|
|
|
|
CDD:224135 |
peptidase M22 |
Protective antigen |
|
4114
|
M28 |
Streptococcus pyogenes |
|
|
|
OZS35741
|
|
|
|
|
|
peptidase M28 |
Protective antigen |
|
4106
|
M6 |
Streptococcus pyogenes |
|
|
|
AAA26920
|
|
|
|
|
CDD:273479 CDD:287215 CDD:279132 |
M6 mature peptide |
Protective antigen |
|
4149
|
maltodextrin-binding proteinSPy1294 |
Streptococcus pyogenes M1 GAS |
|
|
|
NP_269421
|
|
|
|
|
CDD:328725 |
putative maltose/maltodextrin-binding protein |
Protective antigen |
|
4102
|
mrp |
Streptococcus pyogenes |
|
|
|
ANC26187
|
|
|
|
|
CDD:273479 CDD:309295 CDD:330553 CDD:307064 |
Emm-related protein Mrp |
Protective antigen |
|
4139
|
mtsA |
Streptococcus pyogenes |
|
|
|
NP_268747
|
|
|
|
|
CDD:238557 |
metal binding protein of ABC transporter (lipoprotein) |
Protective antigen |
|
4125
|
nuclease |
Streptococcus pyogenes |
|
|
|
ASQ22678
|
|
|
|
|
CDD:225249 |
nuclease |
Protective antigen |
|
4147
|
oppA |
Streptococcus pyogenes M1 476] |
|
|
|
BAM31018
|
|
|
|
|
CDD:226636 CDD:173869 |
oligopeptide-binding protein |
Protective antigen |
|
4150
|
putative protease maturation proteinSpy1390 |
Streptococcus pyogenes M1 GAS |
|
|
|
NP_269488
|
|
|
|
|
CDD:179281 |
putative protease maturation protein |
Protective antigen |
|
4134
|
putative secreted protein SPy0019 |
Streptococcus pyogenes |
|
|
|
NP_268436
|
|
|
|
|
CDD:226400 CDD:226451 |
putative secreted protein |
Protective antigen |
|
4132
|
putative surface exclusion protein SPy0269 |
Streptococcus pyogenes |
|
|
|
ANC26552
|
|
|
|
|
CDD:330553 CDD:275124 |
putative surface exclusion protein |
Protective antigen |
|
4145
|
putative transcriptional antiterminator (BglG family)SPy1325 |
Streptococcus pyogenes M1 GAS |
|
|
|
NP_269442
|
|
|
|
|
CDD:226234 CDD:224676 CDD:238129 |
putative transcriptional antiterminator (BglG family) |
Protective antigen |
|
4104
|
SCPA |
Streptococcus pyogenes |
|
|
|
AAT86469
|
|
|
|
|
CDD:234635 |
ScpA |
Protective antigen |
|
4121
|
scpA |
Streptococcus pyogenes |
|
|
|
ANC27812
|
|
|
|
|
CDD:173801 CDD:239048 CDD:310703 CDD:328787 CDD:291893 |
C5a peptidase protein ScpA |
Protective antigen |
|
4136
|
scpA |
Streptococcus pyogenes M1 GAS |
|
|
|
NP_269970
|
|
|
|
|
CDD:173801 CDD:239048 CDD:310703 CDD:328787 CDD:291893 |
C5A peptidase precursor |
Protective antigen |
|
851
|
SfbI |
Streptococcus pyogenes DSM 2071 |
VO_0012394
|
|
511149
|
WP_014407228
|
|
|
CAA48133.1 |
|
CDD:311998 CDD:331285 CDD:308566 |
fibronectin-binding protein SfbI |
Protective antigen |
S. pyogenes SfbI Protein Vaccine
|
4101
|
shp |
Streptococcus pyogenes |
|
|
|
ANC27645
|
|
|
|
|
CDD:288407 |
heme binding protein Shp |
Protective antigen |
|
855
|
sib35 |
Streptococcus pyogenes serotype M12 |
VO_0012398
|
|
|
90567992
|
|
|
|
|
CDD:286161 |
immunoglobulin-binding protein 35 |
Protective antigen |
S. pyogenes Sib35 Protein Vaccine
|
4131
|
slo |
Streptococcus pyogenes |
|
|
|
NP_268546
|
|
|
|
|
CDD:307453 |
streptolysin O precursor |
Protective antigen |
|
4113
|
spa |
Streptococcus pyogenes |
|
|
|
AIG88580
|
|
|
|
|
CDD:288951 CDD:287215 |
Spa |
Protective antigen |
|
4126
|
spa |
Streptococcus pyogenes |
|
|
|
ACD81471
|
|
|
|
|
CDD:309682 CDD:331876 CDD:330553 CDD:307064 |
streptococcal protective antigen |
Protective antigen |
|
4123
|
speA |
Streptococcus pyogenes |
|
|
|
WP_011285560
|
|
|
|
|
CDD:279467 CDD:280949 |
streptococcal pyrogenic exotoxin SpeA |
Protective antigen |
|
4122
|
speB |
Streptococcus pyogenes |
|
|
|
ANC27833
|
|
|
|
|
CDD:316273 CDD:307663 |
strepotococcal cysteine protease (streptopain) protein SpeB |
Protective antigen |
|
4120
|
Spy0416 |
Streptococcus pyogenes |
|
|
|
NP_268723
|
|
|
|
|
CDD:309682 CDD:173801 CDD:239048 CDD:310703 CDD:273478 |
putative cell envelope proteinase |
Protective antigen |
|
4118
|
Spy0469 |
Streptococcus pyogenes |
|
|
|
NP_268760
|
|
|
|
|
CDD:197609 CDD:331207 |
putative 42 kDa protein |
Protective antigen |
|
4103
|
srtA |
Streptococcus pyogenes |
|
|
|
BAB08162
|
|
|
|
|
|
SrtA |
Protective antigen |
|
4137
|
StreptInCor |
Streptococcus pyogenes |
|
|
|
|
|
|
|
|
|
StreptInCor |
Protective antigen |
|
4148
|
tmbC |
Streptococcus pyogenes |
|
|
|
BAQ53101
|
|
|
|
|
CDD:224658 |
basic membrane family protein |
Protective antigen |
|