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GP from Musoke Marburgvirus

Gene Name GP from Musoke Marburgvirus
Sequence Strain (Species/Organism) Lake Victoria marburgvirus - Musoke
VO ID VO_0010961
NCBI Protein GI 77543430
Other Database IDs CDD:279888
CDD:197367
Taxonomy ID 33727
Gene Strand (Orientation) ?
Protein Name glycoprotein
Protein pI 6.35
Protein Weight 72821.63
Protein Length 755
Protein Note Filovirus glycoprotein; pfam01611
Protein Sequence 
>ABA87127.1 glycoprotein [Marburg virus - Musoke, Kenya, 1980]
MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRW
AFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLW
GAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTG
CFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHT
TSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHN
FSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPT
PSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISL
TLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLR
RLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKD
EQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG
Molecule Role Protective antigen
Molecule Role Annotation Study developed replication-competent vaccines against EBOV and MARV based on attenuated recombinant vesicular stomatitis virus vectors expressing either the EBOV glycoprotein or MARV glycoprotein from Lake Victoria marburgvirus - Musoke. A single intramuscular injection of the EBOV or MARV vaccine elicited completely protective immune responses in nonhuman primates against lethal EBOV or MARV challenges (Jones et al., 2005).
Related Vaccines(s) Adenovirus vectors expressing Marburg virus glycoprotein , CAdVa-Filoviruses (EbMarburg viruses) , cAdVaxM(fus) , Heterologous MARV Protein VLP , Marburg virus DNA prime/boost vaccine DNA/rAd5-GP encoding GP from strain Angola , Marburg virus DNA vaccine DNA-GP encoding GP , Marburg virus glycoprotein expressed by baculovirus recombinants , Marburg virus recombinant vector vaccine CAdVax-Panfilo , Marburg virus recombinant vector vaccine MBGV GP , Marburg virus recombinant vector vaccine MBGV GP/MBGV NP , Marburg Virus Vaccine Ad26.Filo, MVA-BN-Filo , Marburg Virus Vaccine mVLP QS-21 Adjuvant , Marburg virus-like particles , Recombinant VEE Replicons expressing MBGV GP , VSV-based vaccine expressing MBGV GP
References