VIOLIN: Vaccine Investigation and Online Information Network

gD
Gene Name	gD
NCBI Protein GI	19548971
3D structure: PDB ID	1L2G
Other Database IDs	CDD:177571 CDD:186820
Taxonomy ID	10298
Gene Strand (Orientation)	?
Protein Name	glycoprotein D
Protein Length	394
Protein Note	envelope glycoprotein D; Provisional
Protein Sequence	>gi\|19548971\|gb\|AAL90884.1\|AF487902_1 glycoprotein D [human herpesvirus 1] MGGAAARLGAVILFVVIVGLHGVRGKYALADASLKMADPNRFRGKDLPVLDQLTDPPGVRRVYHIQAGLP NPFQPPSLPITVYYAVLERACRSVLLNAPSEAPQIVRGASEDVRKQPYNLTIAWFRMGGNCAIPITVMEY TECSYNKSLGACPIRTQPRWNYYDSFSAVSEDNLGFLMHAPAFETAGTYLRLVKINDWTEITQFILEHRA KGSCKYTLPLRIPPSACLSPQAYQQGVTVDSIGMLPRFIPENQRTVAVYSLKIAGWHGPKAPYTSTLLPP ELSETPNATQPELAPEDPEDSALLEDPVGTVAPQIPPNWHIPSIQDAATPYHPPATPNNMGLIAGAVGGS LLAALVICGIVYWMHRRTRKAPKPIRLPHIREDDQPSSHQPLFY
Molecule Role	Virmugen
Molecule Role Annotation	KOS-gDA3C is attenuated with mutations in gD gene in causing skin lesions at the inoculation and zosteriform sites, yet it is as effective as rKOS-gDA3C in protecting mice against HSV-1 challenge (Awasthi et al., 2008).
Related Vaccines(s)	Herpes simplex virus 1 gD mutant vaccine , Herpes Simplex Virus Type 1 DNA Vaccine encoding 5gP , Herpes Simplex Virus Type 1 DNA Vaccine pRSC-gD-IL-21
References