VIOLIN: Vaccine Investigation and Online Information Network

actA
Gene Name	actA
Sequence Strain (Species/Organism)	Listeria monocytogenes EGD-e
NCBI Gene ID	987035
NCBI Protein GI	16802250
Locus Tag	lmo0204
Genbank Accession	AL591974
Protein Accession	NP_463735
3D structure: PDB ID	1EVH
Taxonomy ID	169963
Gene Starting Position	209469
Gene Ending Position	211388
Gene Strand (Orientation)	+
Protein Name	actin-assembly inducing protein precursor
Protein pI	4.71
Protein Weight	68063.81
Protein Length	639
DNA Sequence	>gi\|16802048:209469-211388 Listeria monocytogenes EGD-e, complete genome AGTGGGATTAAACAGATTTATGCGTGCGATGATGGTGGTTTTCATTACTGCCAATTGCATTACGATTAAC CCCGACATAATATTTGCAGCGACAGATAGCGAAGATTCTAGTCTAAACACAGATGAATGGGAAGAAGAAA AAACAGAAGAGCAACCAAGCGAGGTAAATACGGGACCAAGATACGAAACTGCACGTGAAGTAAGTTCACG TGATATTAAAGAACTAGAAAAATCGAATAAAGTGAGAAATACGAACAAAGCAGACCTAATAGCAATGTTG AAAGAAAAAGCAGAAAAAGGTCCAAATATCAATAATAACAACAGTGAACAAACTGAGAATGCGGCTATAA ATGAAGAGGCTTCAGGAGCCGACCGACCAGCTATACAAGTGGAGCGTCGTCATCCAGGATTGCCATCGGA TAGCGCAGCGGAAATTAAAAAAAGAAGGAAAGCCATAGCATCATCGGATAGTGAGCTTGAAAGCCTTACT TATCCGGATAAACCAACAAAAGTAAATAAGAAAAAAGTGGCGAAAGAGTCAGTTGCGGATGCTTCTGAAA GTGACTTAGATTCTAGCATGCAGTCAGCAGATGAGTCTTCACCACAACCTTTAAAAGCAAACCAACAACC ATTTTTCCCTAAAGTATTTAAAAAAATAAAAGATGCGGGGAAATGGGTACGTGATAAAATCGACGAAAAT CCTGAAGTAAAGAAAGCGATTGTTGATAAAAGTGCAGGGTTAATTGACCAATTATTAACCAAAAAGAAAA GTGAAGAGGTAAATGCTTCGGACTTCCCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGA GACACCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCAGAACCGAGCTCATTCGAATTTCCACCACCA CCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACGCCAATGCTTCTTGGTTTTAATGCTCCTGCTA CATCGGAACCGAGCTCGTTCGAATTTCCACCGCCTCCAACAGAAGATGAACTAGAAATCATCCGGGAAAC AGCATCCTCGCTAGATTCTAGTTTTACAAGAGGGGATTTAGCTAGTTTGAGAAATGCTATTAATCGCCAT AGTCAAAATTTCTCTGATTTCCCACCAATCCCAACAGAAGAAGAGTTGAACGGGAGAGGCGGTAGACCAA CATCTGAAGAATTTAGTTCGCTGAATAGTGGTGATTTTACAGATGACGAAAACAGCGAGACAACAGAAGA AGAAATTGATCGCCTAGCTGATTTAAGAGATAGAGGAACAGGAAAACACTCAAGAAATGCGGGTTTTTTA CCATTAAATCCGTTTGCTAGCAGCCCGGTTCCTTCGTTAAGTCCAAAGGTATCGAAAATAAGCGCACCGG CTCTGATAAGTGACATAACTAAAAAAACGCCATTTAAGAATCCATCACAGCCATTAAATGTGTTTAATAA AAAAACTACAACGAAAACAGTGACTAAAAAACCAACCCCTGTAAAGACCGCACCAAAGCTAGCAGAACTT CCTGCCACAAAACCACAAGAAACCGTACTTAGGGAAAATAAAACACCCTTTATAGAAAAACAAGCAGAAA CAAACAAGCAGTCAATTAATATGCCGAGCCTACCAGTAATCCAAAAAGAAGCTACAGAGAGCGATAAAGA GGAAATGAAACCACAAACCGAGGAAAAAATGGTAGAGGAAAGCGAATCAGCTAATAACGCAAACGGAAAA AATCGTTCTGCTGGCATTGAAGAAGGAAAACTAATTGCTAAAAGTGCAGAAGACGAAAAAGCGAAGGAAG AACCAGGGAACCATACGACGTTAATTCTTGCAATGTTAGCTATTGGCGTGTTCTCTTTAGGGGCGTTTAT CAAAATTATTCAATTAAGAAAAAATAATTA
Protein Sequence	>gi\|16802250\|ref\|NP_463735.1\| actin-assembly inducing protein precursor [Listeria monocytogenes EGD-e] MGLNRFMRAMMVVFITANCITINPDIIFAATDSEDSSLNTDEWEEEKTEEQPSEVNTGPRYETAREVSSR DIKELEKSNKVRNTNKADLIAMLKEKAEKGPNINNNNSEQTENAAINEEASGADRPAIQVERRHPGLPSD SAAEIKKRRKAIASSDSELESLTYPDKPTKVNKKKVAKESVADASESDLDSSMQSADESSPQPLKANQQP FFPKVFKKIKDAGKWVRDKIDENPEVKKAIVDKSAGLIDQLLTKKKSEEVNASDFPPPPTDEELRLALPE TPMLLGFNAPATSEPSSFEFPPPPTDEELRLALPETPMLLGFNAPATSEPSSFEFPPPPTEDELEIIRET ASSLDSSFTRGDLASLRNAINRHSQNFSDFPPIPTEEELNGRGGRPTSEEFSSLNSGDFTDDENSETTEE EIDRLADLRDRGTGKHSRNAGFLPLNPFASSPVPSLSPKVSKISAPALISDITKKTPFKNPSQPLNVFNK KTTTKTVTKKPTPVKTAPKLAELPATKPQETVLRENKTPFIEKQAETNKQSINMPSLPVIQKEATESDKE EMKPQTEEKMVEESESANNANGKNRSAGIEEGKLIAKSAEDEKAKEEPGNHTTLILAMLAIGVFSLGAFI KIIQLRKNN
Molecule Role	Virmugen
Molecule Role Annotation	An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes (Darji et al., 2003).
Related Vaccines(s)	Listeria monocytogenes actA mutant vaccine , Listeria monocytogenes actA/plcB mutant vaccine
References

actA