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E6

Gene Name E6
Sequence Strain (Species/Organism) Human papillomavirus type 16
NCBI Gene ID 1489078
NCBI Protein GI 9627104
Locus Tag HpV16gp1
Genbank Accession AB663688
Protein Accession NP_041325
Taxonomy ID 333760
Gene Starting Position 7124
Gene Ending Position 7600
Gene Strand (Orientation) +
Protein Name transforming protein E6
Protein pI 8.97
Protein Weight 18789.29
Protein Length 158
Protein Note Oncoprotein. It has long been recognized as a potent oncogene and is intimately associated with the events that result in the malignant conversion of virally infected cells.
Protein Sequence
>NP_041325.1 transforming protein E6 [Human papillomavirus type 16]
MHQKRTAMFQDPQERPRKLPQLCTELQTTIHDIILECVYCKQQLLRREVYDFAFRDLCIVYRDGNPYAVC
DKCLKFYSKISEYRHYCYSLYGTTLEQQYNKPLCDLLIRCINCQKPLCPEEKQRHLDKKQRFHNIRGRWT
GRCMSCCRSSRTRRETQL
Molecule Role Protective antigen
Related Vaccines(s) Amolimogene Bepiplasmid , DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 , DNA Vaccine VB10.16 , Host Dendritic Cell Vaccine-001 MSSM/BIIR , HPV 16 E6 (18-26) Peptide Vaccine , HPV DNA Plasmids Therapeutic Vaccine VGX-3100 , HPV E6/E7-encoding Semliki Forest Virus Vaccine Vvax001 , Human Papillomavirus Tumor Antigen Vaccine , Recombinant Vaccinia Viral Vector RO5217790 Vaccine , rMVTT- HPV16-E6/E7 , Synthetic Long E6/E7 Peptides Vaccine HPV-01
References