• Vaccine Name: rMVTT- HPV16-E6/E7
• Target Pathogen: Cancer
• Target Disease: Cancer
• Vaccine Ontology ID: VO_0004761
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• E6 gene engineering:
  • Type: Recombinant protein preparation
  • Description: (Zhi et al., 2002)
  • Detailed Gene Information: Click Here.
• E7 gene engineering:
  • Type: Recombinant protein preparation
  • Description:
  • Detailed Gene Information: Click Here.
• Vector:
  • Vector name:
  • VO vector ID: VO_0001109
  • Description: (Zhi et al., 2002)
• Preparation: (Zhi et al., 2002) In this vaccine, the HPV16 early E6 and E7 genes were expressing by a vaccinia virus TianTan vector.
• Immunization Route: Intramuscular injection (i.m.)

Mouse Response

• Host Strain: C57 BL/6
• Vaccination Protocol: Mice were vaccinated with VmE6E7 (Zhi et al., 2002).
• Vaccine Immune Response Type: VO_0003057
• Challenge Protocol: Mice were challenged by syngeneic HPV16E6 and E7 transformed tumor cells (Zhi et al., 2002).
• Efficacy: The mice vaccinated expressed retarded or prevented tumor development (Zhi et al., 2002).