• Vaccine Name: Escherichia coli ler mutant vaccine
• Target Pathogen: Escherichia coli
• Target Disease: Hemorrhagic colitis
• Vaccine Ontology ID: VO_0002838
• Type: Live, attenuated vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Mouse
• ler gene engineering:
  • Type: Gene mutation
  • Description: This ler mutant is from Escherichia coli (Liu et al., 2009).
  • Detailed Gene Information: Click Here.
• ler gene engineering:
  • Type: Gene mutation
  • Description: This ler mutant is from Escherichia coli (Liu et al., 2009).
  • Detailed Gene Information: Click Here.
• Immunization Route: Oral immunization

Mouse Response

• Persistence: A ler mutant is attenuated in mice (Liu et al., 2009).
• Efficacy: Suckling mice born to mothers immunized with a ler mutant were protected from challenge with wild type E. coli (Liu et al., 2009).