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Vaccine Detail
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Salmonella Gallinarum cbiA/cobS mutant vaccine |
| Vaccine Information |
- Vaccine Name: Salmonella Gallinarum cbiA/cobS mutant vaccine
- Target Pathogen: Salmonella spp.
- Target Disease: Salmonellosis
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Chickens
- cbiA
gene engineering:
- Type: Gene mutation
- Description: This cbiA/cobS mutant is from Salmonella Gallinarum (Penha et al., 2010).
- Detailed Gene Information: Click Here.
- cobS
gene engineering:
- Type: Gene mutation
- Description: This cbiA/cobS mutant is from Salmonella Gallinarum (Penha et al., 2010).
- Detailed Gene Information: Click Here.
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Chicken Response
- Persistence: A cbiA/cobS mutant is attenuated in chickens (Penha et al., 2010).
- Efficacy: A cbiA/cobS mutant induces significant protection in chickens from challenge with wild type S. Gallinarum (Penha et al., 2010).
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| References |
Penha et al., 2010: Penha Filho RA, de Paiva JB, da Silva MD, de Almeida AM, Berchieri A Jr. Control of Salmonella Enteritidis and Salmonella Gallinarum in birds by using live vaccine candidate containing attenuated Salmonella Gallinarum mutant strain. Vaccine. 2010; 28(16); 2853-2859. [PubMed: 20153354].
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