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cobS

Gene Name cobS
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91
NCBI Gene ID 6923296
NCBI Protein GI 205353166
Locus Tag SG2041
Genbank Accession AM933173
Protein Accession YP_002226967
Taxonomy ID 550538
Gene Starting Position 2092942
Gene Ending Position 2093685
Gene Strand (Orientation) -
Protein Name cobalamin synthase
Protein pI 9.13
Protein Weight 24926.05
Protein Length 247
Protein Note catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole
DNA Sequence 
>gi|205351346:2092942-2093685 Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91 chromosome, complete genome
CTCATAACAGAGCCAGCAGAAAGATCAATTCACCAAGTTCGATCGCCGCGCCCAGCGTATCGCCGGTTTG
ACCGCCAAGCGTACGTTTAAGCAACTGGCCAAGGATGAAAATCGCCGCGCATGTGACCACCATTGCGGCC
AACCCTTGCATACCAGGCAGTAATACCGTGGCGACGATTACCGCCAATCCCAGAGTAATGCAGGTTTGCC
GTCCGCTGACTTTACCGATAAATACATTGCCAAGCCCCTCTTCACGGGCGTAGCGATGACGGTACATCAA
TAAAACGGCGCTGCCGCGTCCGGCCGCACAGGCCGCCGCCAACGCCGCCAACATTGGCGTTCCACGTAAC
GCCAGTTCGCTGACCACCAGAATTTTTGCCAGTAGCACAAAAATAAGCGCCAGCCCGCCATGGGTTCCCA
GACGACTATCACGCATAATCTCCAGCATTCGCTCACGGCGGCGCGCGGAAAAAATACCATCGCAGGTATC
GGCCAACCCATCCAGGTGAAAACCACCGGTCAGCAACGCCAGCGCCAGAATACAGAACAACGCCGCTAGC
GGAATACCGCACCAGGGTTGCAGGAGGATGAAAATCAGGCCGCTTACCCCTCCCAGAATCAACCCGATAA
AGGGAAACATCACGATCCCACGCGAATACTGCTCGAAATCCAGTCCCTGCGACCAGCGTGACGGCACGGG
CAAGCGGCTAATAAAAGCGAGCATGGCCCAAAACAGCTTACTCA
Protein Sequence 
>gi|205353166|ref|YP_002226967.1| cobalamin synthase [Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91]
MSKLFWAMLAFISRLPVPSRWSQGLDFEQYSRGIVMFPFIGLILGGVSGLIFILLQPWCGIPLAALFCIL
ALALLTGGFHLDGLADTCDGIFSARRRERMLEIMRDSRLGTHGGLALIFVLLAKILVVSELALRGTPMLA
ALAAACAAGRGSAVLLMYRHRYAREEGLGNVFIGKVSGRQTCITLGLAVIVATVLLPGMQGLAAMVVTCA
AIFILGQLLKRTLGGQTGDTLGAAIELGELIFLLALL
Molecule Role Virmugen
Molecule Role Annotation A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis (Penha et al., 2010).
Related Vaccines(s) Salmonella Gallinarum cbiA/cobS mutant vaccine
References