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purN

Gene Name purN
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3092878
NCBI Protein GI 53718549
Locus Tag BPSL0908
Genbank Accession BX571965
Protein Accession YP_107535
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 1060390
Gene Ending Position 1061052
Gene Strand (Orientation) ?
Protein Name phosphoribosylglycinamide formyltransferase
Protein pI 6.08
Protein Weight 21138.36
Protein Length 220
Protein Note glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
DNA Sequence
>gi|53717639:1060390-1061052 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
GATGAAAAAACTTGTCATCCTGATTTCCGGCCGCGGCAGCAACATGGAGGCCATCGTACGCGCCTGCGCG
CGCGAAGGCTGGCCCGCCGAGGTCGCCGCCGTGATTTCCAACCGGCCGGGCGCGGCCGGCCTCGAATTCG
CGGCGTCGCACGGCATCGCGACGGCCGTCGTCGACCACCGCGCGTTCGACGGCCGCGACAGCTTCGATGC
GGCGCTCGCCGCCGAAATCGACCGCTTCGCCCCCGATCTCGTCGTGCTCGCCGGCTTCATGCGCATTCTC
ACGCCGGCGTTCGTCGCCAAATATGAGGGGCGGATGCTCAACATCCATCCGTCGCTGCTGCCGAGCTTCA
AGGGCATTCATACGCATCAGCAGGCGCTCGACGCGGGCGTCGCGCTGCACGGCGCATCCGTCCACTTCGT
GATTCCGGAGCTCGACAGCGGCGCGATCGTCGCGCAGGCGGCCGTGCCCGTCGTCGCGGGCGACGATGCC
GATGCGCTCGCCGCGCGCGTGCTCGCCGCCGAGCACACGCTGTATCCGCGCGCGGTGCGCTGGTTCGTCG
AAGGCAAGCTGCGCCTCGACGCGGGGCGCGCCATCGTCGCGCCCGACGAGGCGCGCTGGCTGTTCGCGGA
TGCGATCGACACGTCGACGAGCGAGGGCGTATG
Protein Sequence
>gi|53718549|ref|YP_107535.1| phosphoribosylglycinamide formyltransferase [Burkholderia pseudomallei K96243]
MKKLVILISGRGSNMEAIVRACAREGWPAEVAAVISNRPGAAGLEFAASHGIATAVVDHRAFDGRDSFDA
ALAAEIDRFAPDLVVLAGFMRILTPAFVAKYEGRMLNIHPSLLPSFKGIHTHQQALDAGVALHGASVHFV
IPELDSGAIVAQAAVPVVAGDDADALAARVLAAEHTLYPRAVRWFVEGKLRLDAGRAIVAPDEARWLFAD
AIDTSTSEGV
Molecule Role Virmugen
Molecule Role Annotation Although 30:93a purN -immunized mice were challenged with a 10-fold higher dose of WT E8, mice were strongly protected and showed no signs of clinical illness until the experiment was terminated (Breitbach et al., 2008).
Related Vaccines(s) Burkholderia pseudomallei purN mutant vaccine
References