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aroA

Gene Name aroA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhi str. Ty2
NCBI Gene ID 1068996
NCBI Protein GI 29142379
Locus Tag t1956
Genbank Accession AE014613
Protein Accession NP_805721
Taxonomy ID 209261
Gene Starting Position 2006648
Gene Ending Position 2007931
Gene Strand (Orientation) -
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
Protein pI 6.35
Protein Weight 44035.02
Protein Length 427
Protein Note catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
DNA Sequence 
>gi|29140543:2006648-2007931 Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome
ATTAGGCAGGCGTACTCATCCGCGCCAGTTGTTCGAAATAATCAGGGAACGTTTTTGCGGTACATTTAGG
GTCCAGGATCGTGACTGGCGTATCGGACAGTGCGACCAGTGAGAAACACATCGCCATACGGTGGTCGTTG
TACGTGCCAATATCCGCGTGTTGGAGCTTCGCCGGCGGCGTGATACGAATATAGTCGTGCCCTTCTTCGA
CTTCAGCGCCCACTTTACGTAGCTCGGTCGCCATCGCGAACAGGCGATCGGTTTCTTTCACTCGCCAGTT
ATAAATATTGCGCAACGTCGTGGTTCCTTTCGCAAACAACGCCGTGGTGGCAATCGTCATCGCCGCATCC
GGAATATGGTTCATATCCATATCTATGGCGTGCAATTCGCCGCGCGTGCAGGCAATAAAATCATCGCCCC
AGGTAATGGTCGCGCCCATTTTCTCCAGCACATCGGCAAAACGAATATCGCCCTGCATACTTTTGCGGCC
AATCCCGGTCACTTTTACCGTGCCGCCTTTTATCGCCCCAGCGGCGAGAAAATAGGACGCTGACGAGGCA
TCGCCCTCGACCAGATAGCGACCTGGAGAGTGATACTGTTGACCGCCCTTCACGACAAATTGTTGGTAGT
GATGGTTCGCTATCTCCACGCCAAAGGTTTTCATTAAATTTAGCGTGATATCGATGTAAGGTTTTGATAC
CAGTTCGCCTTTAACGCGAATAATTGTGTCTTCAGGCGCCAGCGGCGCCGTCATCAGCAGAGCGGTCAGG
AACTGGCTGGAAACGCTACCATCAACCTCAATGTCGCCGCCGATAAAACCGCCGCGCAGACGCAGGGGCG
GATAGTTTTCCTGCTCCAGGTAATCAATATTCGCCCCACCCTGACGCAGCGAATCGACCAGATGGCCTAT
CGGACGCTCTTTCATACGCGGTTCGCCGGTTAACACTATCTCATTTTGCCCCAGACATAGCGCTGCCGCT
AACGGACGCATCGCGGTTCCGGCATTACCGAGAAACAGTTCCAGAGTGCCTGACGCGCGTAATGGGCCGC
CATTACCCGTGATATCACAGCGGGTGCGATCGGCAGAAAGGGTGTAATTGATCCCCAACGCGCTCAGGGC
ATTGAGCATATGGCGGACGTCATCGCTATCCAGCAGATTCGTCAGAACGGTTTTACCACAAGCTAAAGCC
GCCAGGAGCAAAGCACGGTTTGAAACACTTTTGGAGCCAGGTAAATTAATGGCGCCATCGACCCGCGCGA
TGGGTTGTAACGTCAGGGATTCCA
Protein Sequence 
>gi|29142379|ref|NP_805721.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Salmonella enterica subsp. enterica serovar Typhi str. Ty2]
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADR
TRCDITGNGGPLRASGTLELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANI
DYLEQENYPPLRLRGGFIGGDIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKT
FGVEIANHHYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVL
EKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMAT
ELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
ARMSTPA
Molecule Role Virmugen
Molecule Role Annotation An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. typhi Ty2 (Dougan et al., 1987).
Related Vaccines(s) Salmonella typhi aroA mutant vaccine
References