VIOLIN: Vaccine Investigation and Online Information Network

gltA
Gene Name	gltA
Sequence Strain (Species/Organism)	Helicobacter pylori
VO ID	VO_0012379
NCBI Protein GI	NP_206828
Other Database IDs	CDD:180164 CDD:99867
Taxonomy ID	85962
Gene Strand (Orientation)	?
Protein Name	type II citrate synthase
Protein pI	8.03
Protein Weight	45749.59
Protein Length	500
Protein Note	type II citrate synthase; Reviewed; PRK05614
Protein Sequence	>NP_206828.1 type II citrate synthase [Helicobacter pylori 26695] MSVTLVNNENNERYEFETIESTRGPKAVDFSKLFETTGFFSYDPGYSSTAGCQSKISYVNGKKGELYYRG HRIEDLVAKYKYVDVCKLLLTGELPKNQDESLEFELELRHRSFVHESLLNMFSAFPSNAHPMAKLSSGVS ILSTLYSTHQNMHTEEDYQTMARRIVAKIPTLAAICYRNEVGAPIIYPDIARSYVENILFMLRGYPYSRL KHTTQGEVEITPLEVEAFDKILTLHADHSQNASSTTVRNVASTGVHPYAAISAGISALWGHLHGGANEKV LLQLEEIGDVKNVDKYIARVKDKNDNFKLMGFGHRVYKSYDPRAKILKGLKDELHQKGVKMDERLSEIAA KVEEIALKDEYFIERNLYPNVDFYSGTILRALKIPVRFFTPVFVIGRTVGWCAQLLEHVKSPQARITRPR QVYVGD
Molecule Role	Protective antigen
Molecule Role Annotation	Mice were immunised with the citrate synthase protein by intra-Peyer's patch immunisation. Pre-immunisation with the citrate synthase protein led to a 84-91% reduction in H. pylori infection compared to unimmunised controls (Dunkley et al., 1999).
Related Vaccines(s)	H. pylori GltA Protein Vaccine
References