VIOLIN: Vaccine Investigation and Online Information Network

hspB
Gene Name	hspB
Sequence Strain (Species/Organism)	Helicobacter pylori 85P
VO ID	VO_0012378
NCBI Protein GI	712831
Other Database IDs	CDD:234573 CDD:237231 CDD:239460
Taxonomy ID	210
Gene Strand (Orientation)	?
Protein Name	heat shock protein
Protein pI	5.47
Protein Weight	53926.66
Protein Length	607
Protein Note	chaperonin GroEL; Reviewed; PRK00013
Protein Sequence	>AAC41441.1 heat shock protein [Helicobacter pylori] MAKEIKFSDSARNLLFEGVRQLHDAVKVTMGPRGRNVLIQKSYGAPSITKDGVSVAKEIELSCPVANMGA QLVKEDASKTADAAGDGTTTATVLAYSIFKEGLRNITAGANPIEVKRGMDKAPEAIINELKKASKKVGGK EEITQVATISANSDHNIGKLIADAMEKVGKDGVITVEEAKGIEDELDVVEGMQFDRGYLSPYFVTNAEKM TAQLDNAYILLTDKKISSMKDILPLLEKTMKEGKPLLIIAEDIEGEALTTLVVNKLRGVLNIAAVKAPGF GDRRKEMLKDIAVLTGGQVISEELGLSLENAEVEFLGKAKIVIDKDNTTIVDGKGHSHDVKDRVAQIKTQ IASTTSDYDKEKLQERLAKLSGGVAVIKVGAASEVEMKEKKDRVDDALSATKAAVEEGIVIGGGAALIRA AQKVHLNLHDDEKVGYEIIMRAIKAPLAQIAINAGYDGGVVVNEVEKHEGHFGFNASNGKYVDMFKEGII DPLKVERIALQNAVSVSSLLLTTEATVHEIKEEKAAPAMPDMGGMGGMGGMGGMM
Molecule Role	Protective antigen
Molecule Role Annotation	Orogastric immunization of mice with recombinant H. pylori HspB proteins protected 70% of animals from a challenge dose of 10^4 Helicobacter felis bacteria (Ferrero et al., 1995).
Related Vaccines(s)	H. pylori DNA vaccine pcDNA3.1-hspB , H. pylori HspB Protein Vaccine
References