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ureB

Gene Name ureB
Sequence Strain (Species/Organism) Helicobacter pylori
VO ID VO_0011335
NCBI Protein GI WP_000724295
Other Database IDs CDD:184438
Taxonomy ID 210
Gene Strand (Orientation) ?
Protein Name urease subunit alpha
Protein pI 5.99
Protein Weight 58828.9
Protein Length 638
Protein Note urease subunit beta; Provisional; PRK13985
Protein Sequence 
>WP_000724295.1 urease subunit alpha [Helicobacter pylori]
MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLII
TNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFI
SPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNASNDASLADQ
IEAGAIGFKIHEDWGTTPSAINHALDVADKYDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGG
GHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTL
HDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGIS
EYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAHHGKAKYDAN
ITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKV
SLAQLFSIF
Molecule Role Protective antigen
Molecule Role Annotation Vaccination with poliovirus vector containing the gene for the B subunit of H. pylori urease provides significant prophylactic and strong therapeutic protection against H. pylori in mice (Smythies et al., 2005).
Related Vaccines(s) H. pylori vaccine encoding UreB , SL3261- UreA and UreB
References