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G glycoprotein

Gene Name G glycoprotein
Sequence Strain (Species/Organism) Nipah henipavirus
VO ID VO_0011313
NCBI Gene ID 920955
NCBI Protein GI 13559814
Locus Tag Nvgp5
Genbank Accession AF212302
Protein Accession NP_112027
3D structure: PDB ID 2VWD
Taxonomy ID 121791
Gene Starting Position 8709
Gene Ending Position 11254
Gene Strand (Orientation) +
Protein Name attachment glycoprotein
Protein pI 8.36
Protein Weight 62969.63
Protein Length 602
DNA Sequence 
>NC_002728.1:8709-11254 Nipah virus, complete genome
TAGGACCCAGGTCCATAACTCATTGGATACTTAACTGTATCTTTCTAAGCTATCACATATCAAAGGAGAG
ATTGAATGCTTTTTTGGAGATCTAGATCATTACTATATGTGTCTCCTATAATCACATCATAGGAGTGAAC
CATAATACACATCTTTGGGTAGGGGAAGGAAAGTATTGTTGACGTACTGATTGATCTGCTTGAGTCAAAT
AATCAGTCATAACAATTCAAGAAAATGCCGGCAGAAAACAAGAAAGTTAGATTCGAAAATACTACTTCAG
ACAAAGGGAAAATTCCTAGTAAAGTTATTAAGAGCTACTACGGAACCATGGACATTAAGAAAATAAATGA
AGGATTATTGGACAGCAAAATATTAAGTGCTTTCAACACAGTAATAGCATTGCTTGGATCTATCGTGATC
ATAGTGATGAATATAATGATCATCCAAAATTACACAAGATCAACAGACAATCAGGCCGTGATCAAAGATG
CGTTGCAGGGTATCCAACAGCAGATCAAAGGGCTTGCTGACAAAATCGGCACAGAGATAGGGCCCAAAGT
ATCACTGATTGACACATCCAGTACCATTACTATCCCAGCTAACATTGGGCTGTTAGGTTCAAAGATCAGC
CAGTCGACTGCAAGTATAAATGAGAATGTGAATGAAAAATGCAAATTCACACTGCCTCCCTTGAAAATCC
ACGAATGTAACATTTCTTGTCCTAACCCACTCCCTTTTAGAGAGTATAGGCCACAGACAGAAGGGGTGAG
CAATCTAGTAGGATTACCTAATAATATTTGCCTGCAAAAGACATCTAATCAGATATTGAAGCCAAAGCTG
ATTTCATACACTTTACCCGTAGTCGGTCAAAGTGGTACCTGTATCACAGACCCATTGCTGGCTATGGACG
AGGGCTATTTTGCATATAGCCACCTGGAAAGAATCGGATCATGTTCAAGAGGGGTCTCCAAACAAAGAAT
AATAGGAGTTGGAGAGGTACTAGACAGAGGTGATGAAGTTCCTTCTTTATTTATGACCAATGTCTGGACC
CCACCAAATCCAAACACCGTTTACCACTGTAGTGCTGTATACAACAATGAATTCTATTATGTACTTTGTG
CAGTGTCAACTGTTGGAGACCCTATTCTGAATAGCACCTACTGGTCCGGATCTCTAATGATGACCCGTCT
AGCTGTGAAACCCAAGAGTAATGGTGGGGGTTACAATCAACATCAACTTGCCCTACGAAGTATCGAGAAA
GGGAGGTATGATAAAGTTATGCCGTATGGACCTTCAGGCATCAAACAGGGTGACACCCTGTATTTTCCTG
CTGTAGGATTTTTGGTCAGGACAGAGTTTAAATACAATGATTCAAATTGTCCCATCACGAAGTGTCAATA
CAGTAAACCTGAAAATTGCAGGCTATCTATGGGGATTAGACCAAACAGCCATTATATCCTTCGATCTGGA
CTATTAAAATACAATCTATCAGATGGGGAGAACCCCAAAGTTGTATTCATTGAAATATCTGATCAAAGAT
TATCTATTGGATCTCCTAGCAAAATCTATGATTCTTTGGGTCAACCTGTTTTCTACCAAGCGTCATTTTC
ATGGGATACTATGATTAAATTTGGAGATGTTCTAACAGTCAACCCTCTGGTTGTCAATTGGCGTAATAAC
ACGGTAATATCAAGACCCGGGCAATCACAATGCCCTAGATTCAATACATGTCCAGAGATCTGCTGGGAAG
GAGTTTATAATGATGCATTCCTAATTGACAGAATCAATTGGATAAGCGCGGGTGTATTCCTTGACAGCAA
TCAGACCGCAGAAAATCCTGTTTTTACTGTATTCAAAGATAATGAAATACTTTATAGGGCACAACTGGCT
TCTGAGGACACCAATGCACAAAAAACAATAACTAATTGTTTTCTCTTGAAGAATAAGATTTGGTGCATAT
CATTGGTTGAGATATATGACACAGGAGACAATGTCATAAGACCCAAACTATTCGCGGTTAAGATACCAGA
GCAATGTACATAAAAATCAACCTCATAATTTAATGGATTGATCTAATATAATGATAATAATCGTACAAAG
ACATGTGATGTAAACAAAATTGTTGTAATTAAATAAGTCCTCAGCTGAATACTTTTTTAAGATTAGCAAT
AGCATGTTTTTCCAGTTATTGGATAGTTGATAATATAATTCTGAAACTGGGTTAATAAATAATCTTGATC
GGTGATCTTTGAGAACAATGATATCATATAGTTCATCAAGTGATAATCAATTCTTTATATGTACACTTTA
GAGTATATTTTGAGACTTAGTATTTTCGGCCCGAATGTTAAATTTAATAGTTCATACATAACCTAAACTC
AAGTTCTAAGCATAATGATAACAATTAATGCGAACTTGTCTTGATGTAAGGAAGATTTGATATTAACTGA
GACTCCACTTGATATAGTAGAGCTGAATCTTGTAAATAAATTATAATGAATAGTTTATTCAAAGATTATC
ATTCATATTAGTGTAAATTAAGAAAA
Protein Sequence 
>NP_112027.1 attachment glycoprotein [Nipah henipavirus]
MPAENKKVRFENTTSDKGKIPSKVIKSYYGTMDIKKINEGLLDSKILSAFNTVIALLGSIVIIVMNIMII
QNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINE
NVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVV
GQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVY
HCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMP
YGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSD
GENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQ
SQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQK
TITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT
Molecule Role Protective antigen
Molecule Role Annotation Hamsters were immunized subcutaneously with either 107 PFU of VV-NiV.G or VV-NiV.F expressing the G and F glycoproteins, respectively, or with the two combined. When the VV-NiV.G-vaccinated animals were challenged with Nipah virus 3 months after the last immunization (1,000 PFU/animal intraperitoneally), there was complete protection against mortality (Guillaume et al., 2004).
Related Vaccines(s) ALVAC-NiV-F , ALVAC-NiV-G , NIpah Virus G and F Proteins Subunit Vaccine , Nipah Virus Vaccine rVSVĪ”G-NiVBG , PHV02 , rMV-Ed-G
References