VIOLIN: Vaccine Investigation and Online Information Network

VEGFA
Gene Name	VEGFA
Sequence Strain (Species/Organism)	Homo sapiens
NCBI Gene ID	7422
NCBI Protein GI	76781480
Locus Tag	RP1-261G23.1
Genbank Accession	AF092126
Protein Accession	NP_001020537
3D structure: PDB ID	2VPF
Taxonomy ID	9606
Chromosome No	6
Gene Starting Position	43770208
Gene Ending Position	43786486
Gene Strand (Orientation)	+
Protein Name	transcript variant 1
Protein pI	9.11
Protein Weight	43480.71
Protein Length	412
Protein Note	Also known as VPF; VEGF; MVCD1; MGC70609
DNA Sequence	>NC_000006.12:43770208-43786486 Homo sapiens chromosome 6, GRCh38.p12 Primary Assembly ATCGCGGAGGCTTGGGGCAGCCGGGTAGCTCGGAGGTCGTGGCGCTGGGGGCTAGCACCAGCGCTCTGTC GGGAGGCGCAGCGGTTAGGTGGACCGGTCAGCGGACTCACCGGCCAGGGCGCTCGGTGCTGGAATTTGAT ATTCATTGATCCGGGTTTTATCCCTCTTCTTTTTTCTTAAACATTTTTTTTTAAAACTGTATTGTTTCTC GTTTTAATTTATTTTTGCTTGCCATTCCCCACTTGAATCGGGCCGACGGCTTGGGGAGATTGCTCTACTT CCCCAAATCACTGTGGATTTTGGAAACCAGCAGAAAGAGGAAAGAGGTAGCAAGAGCTCCAGAGAGAAGT CGAGGAAGAGAGAGACGGGGTCAGAGAGAGCGCGCGGGCGTGCGAGCAGCGAAAGCGACAGGGGCAAAGT GAGTGACCTGCTTTTGGGGGTGACCGCCGGAGCGCGGCGTGAGCCCTCCCCCTTGGGATCCCGCAGCTGA CCAGTCGCGCTGACGGACAGACAGACAGACACCGCCCCCAGCCCCAGCTACCACCTCCTCCCCGGCCGGC GGCGGACAGTGGACGCGGCGGCGAGCCGCGGGCAGGGGCCGGAGCCCGCGCCCGGAGGCGGGGTGGAGGG GGTCGGGGCTCGCGGCGTCGCACTGAAACTTTTCGTCCAACTTCTGGGCTGTTCTCGCTTCGGAGGAGCC GTGGTCCGCGCGGGGGAAGCCGAGCCGAGCGGAGCCGCGAGAAGTGCTAGCTCGGGCCGGGAGGAGCCGC AGCCGGAGGAGGGGGAGGAGGAAGAAGAGAAGGAAGAGGAGAGGGGGCCGCAGTGGCGACTCGGCGCTCG GAAGCCGGGCTCATGGACGGGTGAGGCGGCGGTGTGCGCAGACAGTGCTCCAGCCGCGCGCGCTCCCCAG GCCCTGGCCCGGGCCTCGGGCCGGGGAGGAAGAGTAGCTCGCCGAGGCGCCGAGGAGAGCGGGCCGCCCC ACAGCCCGAGCCGGAGAGGGAGCGCGAGCCGCGCCGGCCCCGGTCGGGCCTCCGAAACCATGAACTTTCT GCTGTCTTGGGTGCATTGGAGCCTTGCCTTGCTGCTCTACCTCCACCATGCCAAGGTAAGCGGTCGTGCC CTGCTGGCGCCGCGGGCCGCTGCGAGCGCCTCTCCCGGCTGGGGACGTGCGTGCGAGCGCGCGCGTGGGG GCTCCGTGCCCCACGCGGGTCCATGGGCACCAGGCGTGCGGCGTCCCCCTCTGTCGTCTTAGGTGCAGGG GGAGGGGGCGCGCGCGCTAGGTGGGAGGGTACCCGGAGAGAGGCTCACCGCCCACGCGGGCCCTGCCCAC CCACCGGAGTCACCGCACGTACGATCTGGGCCGACCAGCCGAGGGCGGGAGCCGGAGGAGGAGGCCGAGG GGGCTGGGCTTGCGTTGCCGCTGCCGGCTGAAGTTTGCTCCCGGCCGCTGGTCCCGGACGAACTGGAAGT CTGAGCAGCGGGGGCGGGAGCCAGAGACCAGTGGGCAGGGGGTGCTCGGACCTTGGACCGCGGGAGGGCA GAGAGCGTGGAGGGGGCAGGGCGCAGGAGGGAGAGGGGGCTTGCTGTCACTGCCACTCGGTCTCTTCAGC CCTCGCCGCGAGTTTGGGAAAAGTTTTGGGGTGGATTGCTGCGGGGACCCCCCCTCCCTGCTGGGCCACC TGCGCCGCGCCAACCCCGCCCGTCCCCGCTCGCGTCCCGCTCGGTGCCCGCCCTCCCCCGCCCGGCCGGG TGCGCGCGGCGCGGAGCCGATTACATCAGCCCGGGCCTGGCCGGCCGCGTGTTCCCGGAGCCTCGGCTGC CCGAATGGGGAGCCCAGAGTGGCGAGCGGCACCCCTCCCCCCGCCAGCCCTCCGCGGGAAGGTGACCTCT CGAGGTAGCCCCAGCCCGGGGATCCAGAGAACCATCCCTACCCCTTCCTACTGTCTCCAGACCCTACCTC TGCCCAGTGCTAGGAGGAATTTCCTGACGCCCCTTCTCTTCACCCATTTCCTTTTTAGCCTGGAGAGAAG CCCCTGTCACCCCGCTTATTTTCATTTCTCTCTGCGGAGAAGATCCATCTAACCCCTTTCTGGCCCCAGA GTCCAGGGAAAGGATGATCACTGTCAGAAGTCGTGGCGCGGGAGCCCACTGGGCGCTTTGTCACATTCCA CCGAAAGTCCCGACTTGGTGACAGTGTGCTTCCCTTCCCTCGCCAACAGTTCCGAGTGAGCTGTGCTTTA GCTCTCGTGGGGGTGGGTCAAGGGAGGATTTGAAGAGTCATTGCCCCACTTTACCCTTTTGGAGAAATGG CTTGAAATTTGCTGTGACACGGGCAGCATGGGAATAGTCCTTCCTGAACCCTGGAAAGGAGCTCCTGCCA GCCTTGCACACACTTTGTCCTGGTGAAAGGCAGCCCTGGAGCAGGTGTTTTTTTGGAACTCCAAACCTGC CCACCCAACTTGCTTCTGAAAGGGACTCTAAAGGGTCCCTTTCCGCTCCTCTCTGACGCCTTCCCTCAGC CAGAATTCCCTTGGAGAGGAGGCAAGAGGAAAGCCATGGACAGGGGTCGCTGCTAACACCGCAAGTTCCT CAGACCCTGGCACAAAGGCCTTGGCTACAGGCCTCCAAGTAGGGAGGAGGGGGAGGAGTGGCTGCCTGGC CACAGTGTGACCTTCAGAGGCCCCCAGAGAAGGACACCTGGCCCCTGCCTGCCTAGAACCGCCCCTCCTG TGCTCCCTGGCCTTGGAAGGGGTATGAAATTTCCGTCCCCTTTCCTCCTTGGGGCCCAGGAGGAGTGGAG GGTCCCGGGAGAATATTGTCAGGGGGAAGGCAGGGGGTGTCATGGGAATGGGTGAGGGGGCTGAGGTGCA GAATCCAGGGGGTCCCTGCAGGAGCCGCAGTGGTAAGCTGTCCAGCTGGAAGCCTGGTAACTGTTGTTTT CTCTTGAGAGGGGCTTCCTGTGACCTTGGCTGTCTCTGGGAGCAGGGCTGGGGTACCTGAGTGGGGTGCA TTTGGGGTGTGTGGGAAGGAGAGGGAAAGAAAGATGGACAGTGGGACTCTCCCCTAGCAGGGTCTGGTGT TCCGTAGGCTAGAGTGCCCCTCTGCTCTGCGAGTGCTGGGCGGGAGGGGAGTTGGTGAGAGCTGGAGACC CCCAGGAAGGGCTGGCAGAAGCCTTTCCTTTTGGGTGCTGTCAGGTCCGCATGTCTTGGCGTGTTGACCT TCACAGCTTCTGGCGAGGGGAGGAATGATCTGATGCGGGTGGGGAGGGTTAGAGGAGGCCTCAGGCCTAA GGTGGTGCAGGGGGCCCCCTAGGGGCTGGGCAGTGCCAAGGCATAAAAGCCTTCCCTGGTCCCTGGTGGC ATTTGAAGGTGCCCAGGTGAGAGGGGCTTGGCACCTCCTCACCCTGGGAGGGAGAAGAAACCAGGGAACA GGTAGGAGTGGGAGACAGGTGAGGCTTTGGAAATCTATTGAGGCTCTGGAGAGATTTGTGTAGAGAGGAA AATGTGGTTCTCCCCCAGGGTCTCCTCCTGGGTTTTTACCCTCTAAGCAACCTGTGGGCATGCTGGGTTA TTCCTAAGGACTAGAAGAGCTTGGATGGGGGAGGGTGGTTGGTGCCCTTCGGTCCTCGGCACCCCCCTCC GTCTCCAACACCAGCTCACCCTGGTATTTGTCATGTCAGCAGGAGAAGGTCACCATGTTGTTTTTCTCGC CCCTAGTCCTTCCTTCCTGCCCCAGTCCAAATTTGTCCTCCTATTTGACCTTAATACTTACCATGGCTTT GGACCAGGGAACTAGGGGGATAGTGAGAGCAGGGAGAGGGAAGTGTGGGGAAGGTACAGGGGACCTCGAC AGTGAAGCATTCTGGGGTTTTCCTCCTGCATTTCGAGCTCCCCAGCCCCCAACATCTGGTTAGTCTTTAA CTTCCTCGGGTTCATAACCATAGCAGTCCAGGAGTGGTGGGCATATTCTGTGCCCGTGGGGACCCCCGGT TGTGTCCTGTTCGACTCAGAAGACTTGGAGAAGCCAGAGGCTGTTGGTGGGAGGGAAGTGAGGAGGGAGG AGGGGCTGGGTGGCTGGGCCTGTGCACCCCAGCCCCTGCCCATGCCCATGCCTTGCTCTCTTTCTGTCCT CAGTGGTCCCAGGCTGCACCCATGGCAGAAGGAGGAGGGCAGAATCATCACGAAGGTGAGTCCCCCTGGC TGTTGGATGGGGTTCCCTGTCCTCTCAGGGGATGGGTGGATGGCCTAATTCCTTTTTCTTCAGAACTGTG GGGAGGAAGGGGAAGGGGCACAGGAATATAAGGATCAAGAAAGAAAGAGCTGGGCACCACGAGGTTCACC CTCAGTTTCGTGAGGACTCTCCGCTGTTCAGGTCTCTGCTAGAAGTAGGACTTGTTGCCTTTTTCTTCTG CTCTTTCCAGTAAAATTTTATTTGGAGAAGGAGTCGTGCGCACAGAGCAGGAAGACAGTGTTCAGGGATC CTAGGTGTTGGGGGAAGTGTCCCTTGTTTCCCCTAGCTCCCAGGGGAGAGTGGACATTTAGTGTCATTTC CTATATAGACATGTCCCATTTGTGGGAACTGTGACCCTTCCTGTGTGAGCTGGAGGCACAGAGGGCTCAG CCTAATGGGATCTCTCCTCCCTTCCCTGGTTTGCATTCCTTTGGGGGTGGAGAAAACCCCATTTGACTAT GTTCGGGTGCTGTGAACTTCCCTCCCAGGCCAGCAGAGGGCTGGCTGTAGCTCCCAGGCGCCCCGCCCCC CTGCCCAACCCCGAGTCCGCCTGCCTTTTGTTCCGTTGTGGTTTGGATCCTCCCATTTCTCTGGGGACAC CCTGGCTCTCCCCACCACTGACTGTGGCCTGTGCTCTCCACCTCTGGGGAGGGAAGGCCCTGGGGTCTTC CTTCCCGCGAGTTTCCCTGACCTAAATCTGGCGTGGCTGGGTAGTGGCCAGCAGTGGTGATGCCCAGCCT GTTCTGCCTCCTCCTTCCCCACCCCAGGAGCCCTTTCCTTGGCCTAGGACCTGGCTTCTCAGCCACTGAC CGGCCCCCTGCTTCCAGTGCGCCACTTACCCCTTCCAGCTTCCCAGTGGTCTCTGGTCTGGGAGAGGCAG GACAAAGGTCTTTGTTTGCTGGAGAAAAGGTTGTCTGCGATAAATAAGGAAAACCACGAAAGCCTGGTTG TTGGAGTGTACGTGTGTGCTCCCCCAGGCAGTGGAGGCCAGCCCTCCTTGGAGGGGCGGCTGCCTGATGA AGGATGCGGGTGAGGTTCCCCGCCTCCACCTCCCATGGGACTTGGGGATTCATTCCAAGGGGAAGCTTTT TGGGGGAATTCCTACCCCAGGTCTTTTTACCCTCAGTTACCAACCCCTTGCCCAGGCCAGACCTTCCTGC TATCCCCTCCTGGGCCACAAGCCTGGCCCTCCTCTGTCCCAATTGTGATGAAGGGGCAGTTCAAAACTTC TTGATTAGTCATCTTCTCCCCTATCGACTTGGCTTTAAAAAATGACCTTTTCAGACTTCTAGTCTCGTTC ACTCTTTTTGATGATGCTTTGCCGTAACCCTTCGTGGGTAGAGAAGGATTCTGTGCCCATTGGTGGTCTG GATAAAAGAAATAGAGACCTCACAGGAAGCAGTGGACTGGCCTGTTTCCCCACTGTTCTTTCTGTTTTCA CACCTGTGGCCTTCTCCCCACCTTCTTCCCAATCAACCTATTGTGTACATAGCCCCCCTCATTGTCCTTT ATTCTTCTGGAAAGCAGACCTTGGAGGGAGGAGTGAGGGGGAGGCTCAGCTGTGGTCTCTGGGGGGTGGG GGTTGGGAGCTGGGGTGGAAGTCCACGAAGCATACACTTAAGATGCTTTGGTGAAGTTCTAAACTTCATA TTACCCAGGCTGAAAAAAGAGCACTTGTTCCTAGGGCTGGAAATGGAAGCCAAAACACCACCTTTTTCAG CCTGTTTCAGCATCTTTAGAGATCAGCCCAACCCACTTACACAGTTGAGCAGAGTTGGAGGCCTAGAGAG GGGAGGGACTGGCCCAAGGTCATACCAACTCATGGCCAGAGCCTGGGCCTCCTCACTGGCCAGGTGTTAT TTCTTCCCTCTGGGTAGGGAACCTATTTCAGGGACAGGATTGCTATGTGGTAGTGGTGGTGGGGTGCGAT AGGCGTGGCAGGCTGGGCCACAATTTGGAGTAGTCATGCCAGAGTCCTGCATTTATTTATTCTCAAGGGC CCCGCCTCTGTGGCCCAGAATTACCCCTTCATGCTCCAGTGCACCCCAGGCTTCGTGGCCAGCCTGGGAA ACTGTCTCTACCCTGGTCTCCCTTCAGATCAGCTTCTAGAAATGTTTCGTGGCTACAGTGGCAGCACTGT TTTTTCCATGATGCAAGCAGTTTGCCCTCTTGGGCGGGGTTATCAGTGGCTGGCAGGGCTGGCACAGCGT GTCCGCCCACTGCCACCTGTGGGTTCCAGGAGGGCCCAGCCCCTGTGCTGATGCCCACCACCTTCTCAGC TCATGTCTGGGGAAGAGGACTGGCAGGGGGAAAGGTGCCTCCTCCTGAAAGGTGCCTCCTCTGTTTTTGC CTAATATAGGCTTGGGAACACTTTGATGTCAGCTAATTCTGACTCCTTTACTTACTAGCTGTGCGGCCTT GGGGCAACTTACTTAGCCTCTTTGAGCCTCCTGTTCCCCATCTGTAAAATGGAATCTCAATAGTGTCTAA TAGTACCATGTGGAGAAACTTGTGTGAAATGATAGCTGTGGACTACTGTACACAGTACTCAGGATGTAGT AAGTGCTCAATAAACAGCTGTTGGTATGGTTGACGTTATGGTAGTGGTTGTGGGGAGGACGTAGGAAACT GGAGACTAGCTTGGCAAAGCTGGCTCTTCCTCCTTTTAGGGAAAGCTTAGAGCATCCCCATGGGGTATAC CCATACTCAGACTGTCCTCTGGCATCGAGGTTGGCCCAGGATTCAGTTCAGCTGTCACAGTGAGGTGGCG GGATCAGATGTGGCAGGCCATGTCCCTTGGAACTTGAGTACATCGTGTGATCTCTGGAATGAAAACAGGC CTTCACCAGTGTTGATGGTGGAAAGCTTAGGGAAGTGCTTCAAACACAGTAGGAGGGACTTACGTTAGAT TTTGGAAGGACTTGCCTGATTCGGAAGCTCCAAAGAGTGGCATTACAGAGCTGGGTGGAGAGAGGGGCTA GCCATCTTTTGTGTCGCCCACCGGGCTCATGTGTCATCGCCTCTCATGCAGTGGTGAAGTTCATGGATGT CTATCAGCGCAGCTACTGCCATCCAATCGAGACCCTGGTGGACATCTTCCAGGAGTACCCTGATGAGATC GAGTACATCTTCAAGCCATCCTGTGTGCCCCTGATGCGATGCGGGGGCTGCTGCAATGACGAGGGCCTGG AGTGTGTGCCCACTGAGGAGTCCAACATCACCATGCAGGTGGGCATCTTTGGGAAGTGGGGCAAGGGGGG GATAGGGAGGGGGGTAACACTTTGGGAACAGGTGGTCCCAGGTCGTTTCCTGGCTAGATTTGCCTTGTCT GGCTCCTGCCCCTGAGTTGCACAGGGGAGGTATGGTGGGGTCTTGCCTTCTGTGGAGAAGATGCTTCATT CCCAGCCCAGGTTCCCAGCAAGCCCCAACCATCTCCTTCTCCCTGATGGTTGCCCATGGGCTCAGGAGGG GACAGATGGATGCCTGTGTCAGGAGCCCCTCTCTCCCTCTCTTGGAGAGAGTCCTGAGTGCCCCCCCTTC TTGGGGGCTTTGTTTGGGAAGCTGGATGAGCCTGGTCCATGGAGAGTTTAAAAAGTCTTTTGGTGTTACC TGGTAATGGGGCACATCTCAGCCCAGATAGGGTGGGAGGGAGCTGTGAAACACAGGGAGGGGGTTGCTTT CGGGTATCTACTAGGAGTCAGGGTGAAGCCTAGAGAGGATGAAAGAAGGGGAGGGGATGGGGAGTGGTAA GAACCTAGGATTTGAATTCCCAGCCTGGCCAACCCTTGCAGCCATGTCTTGGCCTCAAGTGGAACAAGGG CTCCTTGAGGCCAGCAGGGTTGGGGGAGTTGGGGTGGGCCTGAGCCTCTTTCCTGCTAGAGCTCTTGGTC CTCCCTGCCTCCACCACCCATCCCTGCTCTGCAGAACCCCTGGGTGCTGAGTGGCAGGAGCCCCAGGGTT GTCCCATCTGGGTATGGCTGGCTGGGTCACTAACCTCTGTGATCTGCTTCCTTCCTTTCCAGATTATGCG GATCAAACCTCACCAAGGCCAGCACATAGGAGAGATGAGCTTCCTACAGCACAACAAATGTGAATGCAGG TGAGGATGTAGTCACGGATTCATTATCAGCAAGTGGCTGCAGGGTGCCTGATCTGTGCCAGGGTTAAGCA TGCTGTACTTTTTGGCCCCCGTCCAGCTTCCCGCTATGTGACCTTTGGCATTTTACTTCAATGTGCCTCA GTTTCTACATCTGTAAAATGGGCACAATAGTAGTATACTTCATAGCATTGTTATAATGATTAAACAAGTT ATATATGAAAAGATTAAAACAGTGTTGCTCCATAATAAATGCTGTTTTTACTGTGATTATTATTGTTGTT ATCCCTATCATTATCATCACCATCTTAACCCTTCCCTGTTTTGCTCTTTTCTCTCTCCCTACCCATTGCA GACCAAAGAAAGATAGAGCAAGACAAGAAAAGTAAGTGGCCCTGACTTTAGCACTTCTCCCTCTCCATGG CCGGTTGTCTTGGTTTGGGGCTCTTGGCTACCTCTGTTGGGGGCTCCCATAGCCTCCCTGGGTCAGGGAC TTGGTCTTGTGGGGGACTTGTGGTGGCAGCAACAATGGGATGGAGCCAACTCCAGGATGATGGCTCTAGG GCTAGTGAGAAAACATAGCCAGGAGCCTGGCACTTCCTTTGGAAGGGACAATGCCTTCTGGGTCTCCAGA TCATTCCTGACCAGGACTTGCTGTTTCGGTGTGTCAGGGGGCACTGTGGACACTGGCTCACTGGCTTGCT CTAGGACACCCACAGTGGGGAGAGGGAGTGGGTGGCAGAGAGGCCAGCTTTTGTGTGTCAGAGGAAATGG CCTCTTTTGGTGGCTGCTGTGACGGTGCAGTTGGATGCGAGGCCGGCTGGAGGGTGGTTTCTCAGTGCAT GCCCTCCTGTAGGCGGCAGGCGGCAGACACACAGCCCTCTTGGCCAGGGAGAAAAAGTTGAATGTTGGTC ATTTTCAGAGGCTTGTGAGTGCTCCGTGTTAAGGGGCAGGTAGGATGGGGTGGGGGACAAGGTCTGGCGG CAGTAACCCTTCAAGACAGGGTGGGCGGCTGGCATCAGCAAGAGCTTGCAGGGAAAGAGAGACTGAGAGA GAGCACCTGTGCCCTGCCCTTTCCCCCACACCATCTTGTCTGCCTCCAGTGCTGTGCGGACATTGAAGCC CCCACCAGGCCTCAACCCCTTGCCTCTTCCCTCAGCTCCCAGCTTCCAGAGCGAGGGGATGCGGAAACCT TCCTTCCACCCTTTGGTGCTTTCTCCTAAGGGGGACAGACTTGCCCTCTCTGGTCCCTTCTCCCCCTCCT TTCTTCCCTGTGACAGACATCCTGAGGTGTGTTCTCTTGGGCTTGGCAGGCATGGAGAGCTCTGGTTCTC TTGAAGGGGACAGGCTACAGCCTGCCCCCCTTCCTGTTTCCCCAAATGACTGCTCTGCCATGGGGAGAGT AGGGGGCTCGCCTGGGCTCGGAAGAGTGTCTGGTGAGATGGTGTAGCAGGCTTTGACAGGCTGGGGAGAG AACTCCCTGCCAAGTACCGCCCAAGCCTCTCCTCCCCAGACCTCCTTAACTCCCACCCCATCCTGCTGCC TGCCCAGGGCTCCAGGACACCCAGCCCTGCCTCCCAGTCCAGGTCGTGCTGAGCAGGCTGGTGTTGCTCT TGGTTCCGTGCCAGCTCCCAAGGTAGCCGCTTCCCCCACACCGGGATTCCCAGAGGTTCTGTCGCAGTTG CAAATGAAGGCACAAGGCCTGATACACAGCCCTCCCTCCCACTCCTGCTCCCCATCCAGGCAGGTCTCTG ACCTTCTCCCCAAAGTCTGGCCTACCTTTTATCACCCCCGGACCTTCAGGGTCAGACTTGGACAGGGCTG CTGGGCAAAGAGCCTTCCCTCAGGCTTTGCCCCCTGCCGGGGACTGGGAGCCACTGTGAGTGTGGAGACC TTTGGGTCCTGTGCCCTCCACCCAGTCTCGGCTTCCCACCAAAGCCTTGTCAGGGGCTGGGTTTGCCATC CCATGGTGGGCAGCGTGAGGAGAAGAAAGAGCCATCGAGTGCTTGCTGCCCAGACACGCCTGTGTGCGCC CGCGCATGCCTCCCCAGAGACCACCTGCCTCCTGACACTTCCTCCGGGAAGCGGCCCTGTGTGGCTTTGC TTTGGTCGTTCCCCCATCCCTGCCCACCTTACCACTTCTTTTACTCCCCCCACCGCCCCCGCTCTCTCTC TGTCTCTGTTTTTTTATTTTCCAGAAAATCAGTTCGAGGAAAGGGAAAGGGGCAAAAACGAAAGCGCAAG AAATCCCGGTATAAGTCCTGGAGCGTGTACGTTGGTGCCCGCTGCTGTCTAATGCCCTGGAGCCTCCCTG GCCCCCAGTACAACCTCCGCCTGCCATTCCCTGTAACCCTGCCTCCCTCCCCTGGTCCTTCCCTGGCTCT CATCCTCCTGGCCCGTGTCTCTCTCTCACTCTCTCACTCCACTAATTGGCACCAACGGGTAGATTTGGTG GTGGCATTGCTGGTCCAGGGTTGGGGTGAATGGGGGTGCCGACTTGGCCTGGAGGATTAAGGGAGGGGAC CCTGGCTTGGCTGGGCACCGATTTTCTCTCACCCACTGGGCACTGGTGGCGGGCCCATGTTGGCACAGGT GCCTGCTCACCCAACTGGTTTCCATTGCTCTAGGCTTCTGCACTCGTCTGGAAGCTGAGGGTGGTGGGGA GGGCAGACATGGCCCAAGAAGGGCTGTGAATGACTGGAGGCAGCTTGCTGAATGACTCCTTGGCTGAAGG AGGAGCTTGGGTGGGATCAGACACCATGTGGCGGCCTCCCTTCATCTGGTGGAAGTGCCCTGGCTCCTCA CGGAGGTGGGGCCTCTGGAGGGGAGCCCCCTATTCCGGCCCAACCCATGGCACCCACAGAGGCCTCCTTG CAGGGCAGCCTCTTCCTCTGGGTCGGAGGCTGTGGTGGGCCCTGCCCTGGGCCCTCTGGCCACCAGCGGC CTGGCCTGGGGACACCGCCTCCGGGCTTAGCCTCCCATCACACCCTACTTTAGCCCACCTTGGTGGAAGG GCCTGGACATGAGCCTTGCACGGGGAGAAGGTGGCCCCTGATTGCCATCCCCAGCAGGTGAAGAGTCAAG GCGTGCTCCGATGGGGGCAACAGCAGTTGGGTCCCTGTGGCCTGAGACTCACCCTTGTCTCCCAGAGACA CAGCATTGCCCCTTATGGCAGCCTCTCCCTGCACTCTCTGCCCGTCTGTGCCCGCCTCTTCCTGCGGCAG GTGTCCTAGCCAGTGCTGCCTCTTTCCGCCGCTCTCTCTGTCTTTTGCTGTAGCGCTCGGATCCTTCCAG GGCCTGGGGGCTGACCGGCTGGGTGGGGGTGCAGCTGCGGACATGTTAGGGGGTGTTGCATGGTGATTTT TTTTCTCTCTCTCTGCTGATGCTCTAGCTTAGATGTCTTTCCTTTTGCCTTTTTGCAGTCCCTGTGGGCC TTGCTCAGAGCGGAGAAAGCATTTGTTTGTACAAGATCCGCAGACGTGTAAATGTTCCTGCAAAAACACA GACTCGCGTTGCAAGGCGAGGCAGCTTGAGTTAAACGAACGTACTTGCAGGTTGGTTCCCAGAGGGCAAG CAAGTCAGAGAGGGGCATCACACAGAGATGGGGAGAGAGAGAGAGAAAGAGAGTGAGCGAGCGAGCGAGC GGGAGAGCGCCTGAGAGGGGCCAGCTGCTTGCTCAGTTTCTAGCTGCCTGCCTGGTGACTGCTGCCTTCT CTGCTTTTAAGGCCCCTGTGGTGGGCTGCAGGCACTGGTCCAGCCTGGCGGGGCCTGTTCCGAGGTTGCC CTGGTTGCCTGAGTGGTAGGCTGGTGTGGCTTAGTGTAGTGGTGTGGACGCAAGCTGTGTGTTGTGTCCT GTGGTCCTTCTGCTCATAGTGGCTGTTGGTCCTGATGTTATTACTACCTCTGGTAGTAATGCTGAGAAGC TGAAAGCCGATTCCAGGTGTGGACAATGTCAACAAAGCACAGATGCTCTCGCTGGGGCCTTGCCTCGGCC CTTTGAAGTCTGCATGGCTGGGCTTCTCACTCACTCAGTGTTTCTTGCTGGGGGAAGGAATTGAGTCTCC CACTTCAGACTGGGCCTCCCTGAGGAAAGGGTTGTGTCTCCCCACTCAGACTGAGGTTCCCTGAGGGTAG GGCTGTGTCTCTCCCCTCCGACCTGGGCTCCCTGATAGGGCTGTCTCCCCGCTCAGACTGAGGCTCCCTC AGGCCAGGGCTATGTCTCCCTCCTCAGACTGGGGCTCTGAGGGCAAGGGGTCTGGCTGTTCGTTTAGGAT GGGGCACTTTTGCCTACACACTGAAGGAGCTGTAGCATCCAAGAATACTAGATACCTTTAATCCTCCACC AGTCATGGTGACAACCCCAAGCAGCCCACACATTTTCAAGTGCCCCCAGGATGCGTGGAGGGAGGGGTCT GTGCCCATTCTCCTGACATTAGCCTGTGAGCTCCGTAAGCCCGGGCCTCGTTTACGTACCTTTGTGAGCC CCGGGCATCTGTACCTCTTTCCTTTGCCCATACTGGGGACCAAGGAAGTGTCAAGTGCATGAGTGAATGT GTGACTCAGTTCAGAGGGTGAGGTCAGGAGCACAGGGTCGGGACAGGTGGCTGGCATCTTTTAATGCCTT AGCTTATGTTCTTTATACCAACTTGGCCTGTGCTCAGAGTGAGGGAGGCCCTGGGGGTCAGGGTAAGCGT CAGTCAGGGAGGCAAGACTTTGTGGGGATTTCCTAGACAGGGCCAAGGCACCCCCAGCTCACCCCGAGGC TGTGTTAGGGAAGTCCTTGGAGTGTCTCCCCTCCCCCAGCAATGTTCTTGTGGCTTGTGTGTGCTCAGGG GATGCTGGGAACCAGGCCTGGGTAGTTGGTGTGGGGTGCTGTCTGTCTTGGCCCTATGTGAAACCAAGAG GGCGTATATTAGTGCTGGGGTGGGGGCTCTGCCTAACTTCAGGGCTGGATGAGGGGAGTCTCAGTTCCCC AGGGGTCCTTGGGAAAGATAAGGGACTTGACATTTTAGGGTTTTTAGGTGATTATTCTGCTGATGGGGGT TTGTGTGAAGTGACCTGGGAGCTAACTGAAGTTACTCTAACCTCCCAATACCTTTACCCAACCCCCAAGC TGGCTGTATCTGGGAATATCAGTTTCCAAAATTGGAGGCTTAGGACTCCGTTTCGGGGCTCCCCAGAAGG GTAGGGCCTGTTCTGCCTCCTTCTCACAATCACCCAGGGGCAGGGGCATGCTGAGAAAGTTCTTGGAGGC CCCCTTTGCTTCAGCTGGAGTAGTGAAGCCGCCGAATTGTCTCTCCCCATCCTAAGTGAAGCAGCATATT TGAAAGGAAAGACAACCTGTTACCTGGGCCTGCAACCTCCAGGCAGCTCAAGAGAGATGAGGCCTACAGC CACAGTGGGAGGGGACATGGGGAATGGAGATGGTCCCTCACCTTCCTGGGGCCTCCTGCTCTACGCTACC CCCTCGGGAGCCTCCTGTCCCCAGGGCAGGCCCTTGCCATTGTTGGTCACCCGGCCAAGCCTCTCTGCCT CAGGCGTTCTCCCAGAAGATCTGCCCACTCTCTTCCCCACACCAGCCCCTAGAGACTGAACTGAAAACCC TCCTCAGCAGGGAGCCTCTTCTGATTAACTTCATCCAGCTCTGGTCACCCATCAGCTCTTAAAATGTCAA GTGGGGACTGTTCTTTGGTATCCGTTCATTTGTTGCTTTGTAAAGTGTTCCCATGTCCTTGTCTTGTCTC AAGTAGATTGCAAGCTCAGGAGGGTAGACTGGGAGCCCCTGAGTGGAGCTGCTGCTCAGGCCGGGGCTCC CTGAGGGCAGGGCTGGGGCTGTTCTCATACTGGGGCTTTCTGCCCCAGGACCACACCTTCCTGTCCTCTC TGCTCTTATGGTGCCGGAGGCTGCAGTGACCCAGGGGCCCCCAGGAATGGGGAGGCCGCCTGCCTCATCG CCAGGCCTCCTCACTTGGCCCTAACCCCAGCCTTTGTTTTCCATTTCCCTCAGATGTGACAAGCCGAGGC GGTGAGCCGGGCAGGAGGAAGGAGCCTCCCTCAGGGTTTCGGGAACCAGATCTCTCACCAGGAAAGACTG ATACAGAACGATCGATACAGAAACCACGCTGCCGCCACCACACCATCACCATCGACAGAACAGTCCTTAA TCCAGAAACCTGAAATGAAGGAAGAGGAGACTCTGCGCAGAGCACTTTGGGTCCGGAGGGCGAGACTCCG GCGGAAGCATTCCCGGGCGGGTGACCCAGCACGGTCCCTCTTGGAATTGGATTCGCCATTTTATTTTTCT TGCTGCTAAATCACCGAGCCCGGAAGATTAGAGAGTTTTATTTCTGGGATTCCTGTAGACACACCCACCC ACATACATACATTTATATATATATATATTATATATATATAAAAATAAATATCTCTATTTTATATATATAA AATATATATATTCTTTTTTTAAATTAACAGTGCTAATGTTATTGGTGTCTTCACTGGATGTATTTGACTG CTGTGGACTTGAGTTGGGAGGGGAATGTTCCCACTCAGATCCTGACAGGGAAGAGGAGGAGATGAGAGAC TCTGGCATGATCTTTTTTTTGTCCCACTTGGTGGGGCCAGGGTCCTCTCCCCTGCCCAGGAATGTGCAAG GCCAGGGCATGGGGGCAAATATGACCCAGTTTTGGGAACACCGACAAACCCAGCCCTGGCGCTGAGCCTC TCTACCCCAGGTCAGACGGACAGAAAGACAGATCACAGGTACAGGGATGAGGACACCGGCTCTGACCAGG AGTTTGGGGAGCTTCAGGACATTGCTGTGCTTTGGGGATTCCCTCCACATGCTGCACGCGCATCTCGCCC CCAGGGGCACTGCCTGGAAGATTCAGGAGCCTGGGCGGCCTTCGCTTACTCTCACCTGCTTCTGAGTTGC CCAGGAGACCACTGGCAGATGTCCCGGCGAAGAGAAGAGACACATTGTTGGAAGAAGCAGCCCATGACAG CTCCCCTTCCTGGGACTCGCCCTCATCCTCTTCCTGCTCCCCTTCCTGGGGTGCAGCCTAAAAGGACCTA TGTCCTCACACCATTGAAACCACTAGTTCTGTCCCCCCAGGAGACCTGGTTGTGTGTGTGTGAGTGGTTG ACCTTCCTCCATCCCCTGGTCCTTCCCTTCCCTTCCCGAGGCACAGAGAGACAGGGCAGGATCCACGTGC CCATTGTGGAGGCAGAGAAAAGAGAAAGTGTTTTATATACGGTACTTATTTAATATCCCTTTTTAATTAG AAATTAAAACAGTTAATTTAATTAAAGAGTAGGGTTTTTTTTCAGTATTCTTGGTTAATATTTAATTTCA ACTATTTATGAGATGTATCTTTTGCTCTCTCTTGCTCTCTTATTTGTACCGGTTTTTGTATATAAAATTC ATGTTTCCAATCTCTCTCTCCCTGATCGGTGACAGTCACTAGCTTATCTTGAACAGATATTTAATTTTGC TAACACTCAGCTCTGCCCTCCCCGATCCCCTGGCTCCCCAGCACACATTCCTTTGAAATAAGGTTTCAAT ATACATCTACATACTATATATATATTTGGCAACTTGTATTTGTGTGTATATATATATATATATGTTTATG TATATATGTGATTCTGATAAAATAGACATTGCTATTCTGTTTTTTATATGTAAAAACAAAACAAGAAAAA ATAGAGAATTCTACATACTAAATCTCTCTCCTTTTTTAATTTTAATATTTGTTATCATTTATTTATTGGT GCTACTGTTTATCCGTAATAATTGTGGGGAAAAGATATTAACATCACGTCTTTGTCTCTAGTGCAGTTTT TCGAGATATTCCGTAGTACATATTTATTTTTAAACAACGACAAAGAAATACAGATATATCTTAAAAAAAA AAAAGCATTTTGTATTAAAGAATTTAATTCTGATCTCAA
Protein Sequence	>NP_001020537.2 vascular endothelial growth factor A isoform a [Homo sapiens] MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLGCSRFGGAVVR AGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCADSAPAARAPQALA RASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMA EGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEES NITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGAR CCLMPWSLPGPHPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
Molecule Role	Protective antigen
Molecule Role Annotation	A protein vaccine candidate, based on a human modified VEGF antigen that is expressed at high levels in E. coli was developed. With respect to controls, immunization experiments in C57BL/6 mice using weekly doses of this antigen and three adjuvants of different chemical natures show that time for tumor development after subcutaneous injection of Melanoma B16-F10 cells increases, tumors that develop grow slower, and overall animal survival is higher. Immunization also prevents tumor development in some mice, making them resistant to second tumor challenges. Vaccination of mice with the human modified VEGF recombinant antigen produces antibodies against the human antigen and the homologous mouse VEGF molecule. We also show that sera from immunized mice block human VEGF-induced HUVEC proliferation (Morera et al., 2008).
Related Vaccines(s)	Cancer VEGFA protein vaccine , hVEGF26-104/RFASE Peptide Vaccine , LY6K/VEGFR1/VEGFR2 Multipeptide Vaccine , PAX3/FKHR Peptide Vaccine , URLC10-TTK-KOC1-VEGFR1-VEGFR2 Multipeptide Vaccine , VEGFR-2 DNA Vaccine VXM01 , VEGFR2-169 Peptide Vaccine
References

VEGFA