VIOLIN: Vaccine Investigation and Online Information Network

TERT
Gene Name	TERT
Sequence Strain (Species/Organism)	Homo sapiens
NCBI Gene ID	7015
NCBI Protein GI	301129200
Genbank Accession	AB016767
Protein Accession	NP_001180305
Taxonomy ID	9606
Chromosome No	5
Gene Starting Position	1253166
Gene Ending Position	1295046
Gene Strand (Orientation)	-
Protein Name	transcript variant 4
Protein pI	11.27
Protein Weight	112208.51
Protein Length	1069
Protein Note	Also known as TP2; TRT; EST2; TCS1; hEST2
DNA Sequence	>NC_000005.10:1253166-1295046 Homo sapiens chromosome 5, GRCh38.p12 Primary Assembly ATTTTTTTCAAAACTGAAAAACTCATATATTCAGTATTTTACTCCCACAGCACCTCCCCCCAATTTGACC CACAGGGACCCCCATCCAGGTGCAGGGTCCTCGCCTGTGTACAGGGCACACCTTTGGTCACTCCAAATTC CCAGAGCTCCCAGGGTCCTTCTCAGGGTCTCCACCTGGATGGTGGGGGTGGAAGGCAAAGGAGGGCAGGG CGAGGGGTGAACAATGGCGAATCTGGGGATGGACTATTCCTATGTGGGGAGTGGAAGCCGGGCTCCTGGT GAGGAAAAGCTGGCCCTGGGGTGGAGCCGAGCGCCAGCCTGTGGGGAAGTGAAGACGGCAGGTGTGCTGG ACACTCAGCCCTTGGCTGGACACTCGCTCAGGCCTCAGCCGGACACTCAGCCTTCAGCCGGACATGCAGG CCTCGGCCAAACACTCACTCAGGCCTCAGACTCCCAGCGGTGCGGGCCTGGGTGTGGGCCGCCCCTCCCT CCCTGGGACGTAGAGCCCGGCGTGACAGGGCTGCTGGTGTCTGCTCTCGGCCTGGCTGTGGGCGGGTGGC CATCAGTCCAGGATGGTCTTGAAGTCTGAGGGCAGTGCCGGGTTGGCTGCGGCCTCCAGGGCAGTCAGCG TCGTCCCCGGGAGCTTCCGACTCAGCTGCGTCTGGGCTGCGGGGCCAAAATCAGACTCCGTTCCAGAAGA GGCCAGAGGTGGCATCCTCCAACCCTCCTAGGACGTGTGGGTGGCCGGGCAGGCAGGGCCTGCACCTCGT GGCCCTGGCTGGTGGGAACCTCAGTGAAGGGACAGACACCCCTCCACCGGGGCGAGCAGACAGGCAGCCC AGTGACGCTGGAGCGGCGGGGCGGGGAGAGAACTTGCTCAGGACCCCAGGAGCTCAGGGCAGCAGCCAGG GAAGAGGCTGTGAGAGGACACAGGTCAGGGGTCAGAAGGCTCCCAAGCGTGGGGAGCCATCGCCCCTGAG ATGGGAAGCAGGGGTTCAAGAAGTTGTGGACCCTGCCAGGCTCCGTGGCCTGGGGACACCAGCGTTTAAT CACATAGGGCTGCCAGCGTGGCTCCAGGCCCCCAGGGTCAGGCCCGGGGGCGTCTGCACTTCAGCAGCAT CTGAGGCTGCTCGCCCCACACAGGGCGTTCAAGGATGACCCCTGGGCAGGTGGGGCCCGCACTGGCCTCC ACCCACACTTGCCTGTCCTGAGTGACCCCAGGAGTGGCACGTAGGTGACACGGTGTCGAGTCAGCTTGAG CAGGAATGCTTGGTGGCACAGCCACTGCACGGCCTCGGAGGGCAGAGGGCCGGCGGCGCCCTTGGCCCCC AGCGACATCCCTGGGGGAAAACAGAGGCTGAGGAGTCACAGGCCCAGCCCAGCTCCCCTCCCAGGAGACA CCGGAAAGCTGCCCACACCCGACGGTCTGCGGGGTGGCTCCATCTCTGGCTGTCCCGACCCAAGCACCGC AGGAGTCACGACAGAAATGTTTTCTTCGGCTTCTCCAGGTGAAATTTCCACAACACAGAAAGAACAGAAA GTAGAAGCTGTTAAGCTCAGGACCGCAGGTTCGACATGGCTTGAATTTCAGACGGATCAGAAACCTCCCT GATGCTGGACAAAGTGTCCAGGGGCAGAGGACGGTGACTGGGAAGCAGAGGACGGCGCGGGGCTCTGTCG TGGTGATACGCGGCCTCTGCTCCTGAGAGGGGTGGGGTAGCCTGGGCCTGGCCTCCTCCTAAGCCCTTGG CCTGGGTTTGCACAAGGGCCCTAAGTGCCATGGACGGGAGACAGCCCAATCCCACCACAGGGCAAACAGG AGAGGCCAGGCCCCCCAAATCCCACCATGGGGCAAACAGGAGAGACCAGGCCCCCCAGCGCTTCCCCAGG CAGAGCAAGGTGGGAAGGATGGCAGCTCCCAGACAGCTCCTGTCCCTTCCATCAGGTGCTCTGCTCACCC CACGAGAGGGCGGGCAGACGAGCCTGACAGTGGTTGGGTTAAACCACTTCCTGATGCGAAAAGGGGTAAG AACTTCCTAAGCCCAGATTCACTCAGTCTCCTGACACACTAACACCAGCAGGCAGGCACTGCTGCCACTG AGGCCAGGCACCTGCACATACCTGCGTTCTTGGCTTTCAGGATGGAGTAGCAGAGGGAGGCCGTGTCAGA GATGACGCGCAGGAAAAATGTGGGGTTCTTCCAAACTTGCTGATGAAATGGGAGCTGCAGCACACATGCG TGAAACCTGAGAGGATGGCGGACAGCGTCAGAGGAAAGGCCTCCTAATCAGACGGTGCTCGTGGGTGTGG GCATGGGCCCACCGGTGCCTGTGTGCGTGCATGAATGCACATGCATGGGTTTCCTCATGGGCACAGGTGC ACACACACGGATGCATGCATGCATGTCTGTGTGTGTGCTTGTGTGTGCGAGTAGCTGCGTGTCTGTGTGT GCACAGGTACACTGCGTTTCTGTGCACCATCTGTATGAACACGCATGTGGAGGCTGAAGCAGCTCCATCC TGGATGCCAGCCCCCCATGCTGGCTTCTGATTAGCCCCTGTTCCGGGAAGGCCTCTAAGGTTTCCAGTTT ATCCATTGTTCCTTGTGTACCAGCAGGTACTTATCATGAATCCTGCCCTTCGTCAGACAACCTTGATGTC ATCGTATATCAACGTCCTGCGCATCCCTTCTGAGCCACCCGCCCCTGTGGTGCATAAACCCTGGGTCTGG GGTGATGGTGTGAGGACCCATCATCTCATCTCACTGACACCGAGACACCGACTTGGCTTCTGTGTGTAGG TTAAGTTCCTACTAAATGTTTCTTTCCAAGAAACTGCATTTGTCAGTCTTCTTTGTTGTTGTTGAGATGG GCTCTCACTCTGTCACCCAGGCTGCAGTACAGTGGTGCAATCTCAGCTCACTGCAGCTTCCACCTCCTGG GCTCAAGTGATCCTCCCACTTCAGCCTCCCAAGTATTGGAACTACAGGCGCACACCACCATGCTCAGCTA ATTTTTGTTTTTATTTTTCATAGAGATGGGGTTCTACTATGTTGCTCAGGCTGGTCTTAAACTCCTGGGC TCAAGGGATCCTCTCGCCTCGGCCTCCCAAAGTGCTGGGACTACAGGTGTGAGCCACCGCGCCAGCCCTG TCAGCCTCCATCTTTGGCCTCTCAGCTTCCTGGGACTTTGGGGCAGGTGTGCACAGACCTGGCTACCATG AAACAGCACATGTGCACATGTGCTCATATGTGCGTGTGATCAGAGCCCCCGTGTACCTGGTCTGACCCTC TGCCTGAGCCCCCCGTGTACCTCATCTCACCCAGTGCCTGAGCCCCCCATGTACCTGGCCTCACCCACTG CCTGAGCCCCCCGTGTACCTCATCTCACCCACTGCCTGAGCCCCCCATGTACCTGGTCTCACTGACTTCC TGAGCCACTTCTGGAATGACCTGAGATCACACCAGTCAAGCCAGCACCCCGGTTTCAGCCTCTCAGTAAC TCTGCTGAGGTGGGATGTCTTTTCCCCATTTAGCAACAACGGAAGCCAGGCCCAGAATGTTTTTAAACAA ATAAATAAGCCTAAGGTCCCGGGGTTGCCACACGGCCACGCTCCTGACCCAGGAGGGAAACACCTAGCAT GGGTGAGGGGCTCTCTTCCAAAGGGAGAAATAGCCACCTGCTAGAGGTCGGGGCGTCCACCCCAAGCCCG TGTGGAGGCGCGGCCAGCACGGGCCAGGAAGGCCGAGCCCCAGCGGATTTGAATCAGACCCCGCCCCCAG CGCCACGTGGACCACCACAGCCTCGCCCACTGCAGCCTGGCTGCCGTGAAATCGGGGCCCAGCTCTCCGT TCTCCCACTCCTGCCTCGAGGGAAGGGGATTCCTGGGCCTTCCACGTGCCTGACTCTGTGTTTGGAAACG GCCCGTGGCCCATCGCATCTCGGCCTCCTCAGGGCTACCCAATCAAGCGACTACCCAAGGGTCCCCACAT GGGTGGGGAAACTCAGCCGCCCTGCCCTGAGCCCAGGCCCTCTACGGGAGCTCCTCGGAGCTAGAGACCC TGGTGGGGAAATGAGGACAAGACTGAGCTGAATATGGGAGGAGCAGGTGGCAGGTCACATGGCCCTGGGA GTTTCCCAGGAGTTTTCACCTGGGAAAACTCCTCTGACCTCATCATGGCCCAAGGAGGCCCCAAGCACGC CAGCTGGACCCTGGGGTCAACCACAGTGTCAGACACCTCCAGTCCTCAGTGGCACCTGTATCCAGCACAC CCCAAGGGTTTCCGGAAAGGAGTCAAGCAGCTTGCACGAGGGCCCAGGCACGCGTCAGGGAGATGCAAAC GAGGGAAGATTTGAGGCAGAGAGAGAAGGCAGAGAGGAGGGCGGTCTGAGCCGGACGCACCCTGGAACTG AGACAGCCTGGTCCCAAGCCTCTGGAGCTGGTGCAAAGGCGGTAACATGCAGCTGTGGCTCTGCCCTCCC TGCCAGAGCATGAAGGCGCAAGCACTCGGGTTAAAAACCATTTTCATGGTACGACCTTGTAATGGAAAAC TCTCCCGTGAGCCCTTGCTGGGTTTCCACGATAGACGACGACCTCATTTCACATCAAGTGTGCACGGTAA TTCGCGCAGCCTCGGCCCTGGGTAACACAAATGCTCACACTCCTTCTCAGCCCTCATGGGGCGAGGGCTT CGGCCTCCTGGCATTCAGCTCCCAGTGGCTCGGGAGGCCTGTTGAGGTGGAGGCCCGGGCCTGTGGTGCC CGACTGCCCTTTGGTACAGCCCCGAGGCTTGTGCCACCACCTGCCCTGACTCCAGGCAGAAGCTGGCCCT GTGGCCTCCACAGATTGGCCCTTCCCTCTGTGATAAAGTTGTCGATTCTTGGCAGGGGCACCCCCTGACC AGCCAGGACAGGGAACGTTCCAGGAGCACAGCCATGCCCAGAGCACAGGTGCTGGCCGGGCTGTGTGGGG AGCCACAGCTCTGCTGCACCTTCCCGGGGGTGGGGCCAGCGACCCTCACCTGCACCCACCTCGGCCCTCT TTGCTGAGACCCCAAATCCTCCGGGCATCTGATCTCCCATCTACTGTTCAGACACCTTCCCAGCCTCCTC TGCTAAGACTCCCCATAAACATCTCTTTACCCCATGCCCCTGCTGCCCTGGGATGGCCTCCATGACGTCC CACGGCCAGTGCACAGGCACAGTGGGGACACCTGGGGCCACACCGGCTCCTACCACTACCCAGAGATGGA GAACAGGTGCTTTGCACAGAGCCACGCGAACAGAACTGTGCACAGGCAGCAGCACCACTGAAAACGTAAG ACATTCCTTGCCCCTAAAACCCAGGAGTTCCAAGGTGAAGCCCCGGGTCAGAGGTGAGCAGAGCGCGGAG GGTCCCTGGAGGCTGGGCCTGCACCCCTTGGTGGCGGCTCACCTGTACGCCTGCAGCAGGAGGATCTTGT AGATGTTGGTGCACACCGTCTGGAGGCTGTTCACCTAGAGTCGCCAAGAAAGAGTGAGAAACGGTAGAAA CCTCTCTGGGATTTTAAGTTTTTACTTTTTGCTTTATCATCCATTCAGATGGAACAAGAAAGAGGAACAT TTTGACAAGAAACTATCCCTCTTCCCAGTGAAATCCGGCCTGGCCCTCACCCGGCAGCTGCGAACCACCC TGGGCGAGTCAAGACTCTGTGTCATCTGCCTGCCCCCGAGGCTCGGCCAAGACAGGAAGGAACCAGGAGA GGGAGTGGACGCAAATGCCCACAGAGAGGGGAGGTGGACGCAGATGCCCACAGAGAGGGGGAGTGGACGC GGATGCCCACAGGAGAGAGGGAGTGGAGTGGATGTAAATGCCCACAGGAGAGGGGGAGTGGACACAGACG CCCACAGGAGAGAGGGAATGGAGTGGATGTAAATGCCCACAGGAGAGGGGGAGTGGACACGGACGCCCAC AGGAGAGAGGGAGTGGATGCAGATGCCCACAGGAGAGGGAGTGGACGCGGATGCCCACAGGAGAGGGGGA GTGGAGTGGATGCAGATGCACACAGGAGAGGGAGTGGACGTGGATGCCCACAGGAGATGGAGTGGATGCA GATGCCCACAGGAGAGGGAGTGGACGCGGATGCCCACAGGAGAGGGAGTGGACGCAGATGCCCACAGGAG AGGGAGTGGACATGGACGCCCACAGGAGAGAGGGAGCAGACGCAGATGCCCACAGGAGAGGGAGTGGATG CGGACGCCCACAGGAGGGGGGAGTGGACACGGACGCCCACAGGAGAGAGGGAGCGGACGCAGATGCCCAC AGGAGAGGGAGTGGACGCGGACGCCCACAGGAGGGGGGAGTGGACACGGACGCCCACAGGAGAGAGGGAG CAGACGCAGATGCCCACAGGAGAGGGAGTGGACGCAGATGCCCACAGGAGAGGGAGTGGACATGGATGCC CACAGGAGAGGGGGAGTGGACACGGATGCCCACAGGAGAGAGGGAGTGGACGCAGATGCCCACAGGAGAG GGGGAGTGGACACGGACGCCCACAGGAGAGACGAGTGGATGCAGATGCCCACAGAAGAGGGAGTGGACGC GGATGCCCACAGGAGAGGGGGAGTGGACACAGACGCCCACAGGAGAGAGGGAGTGGATGCAGATGCCCAC AGGAGAGGGAGTGGACGCGGACGCCCACAGGAGGGGGGAGTGGACACGGACAACCACAGGAGAGAGGGAG TGGACACAGATGCCCACAGGAGAGGGAGTGGATGCGGATGCCCACAGGAGAGGGGGTGTGGACGCCCACA GGAGAGGGGGAGTGGACACAGAAGCCCACAGGAGAGGGAGTGGACGCGGATGCCCAGATGGGACAATGCC CTCAGGGCTGCAGCTTCAGAGCCTCAGCCCACCAAGGCCTGGGACCCCGTCTCATCCTGTAAGGAGTGGC ACTGGTGCTGAGGACCTAGCGGGGTGAACACGAGGACCCCTCAATACATGTTATGTGCACACATGCTACT CACACTGCACACCCACACGCATGCACCTCACGTGAATGCCCACACGACTGTGCACGAACACACATGCATG TCAGGTGTGCATTCGCATGTGCACACACTTGTGCCCTTGCACACCTGTGCACACACTGCCATGCCTTCAT GTACACACATGCACACATGTATGTGCTCACGTGTATATGCGTACATGTGCACTCTTACGTGCAGCCAGTC ACCATCAGCCTTGCAGGCACGCGCGCACACACACACACACATACTTGCGCACACACCTCCTGAACTCTGA ACTCTGTGCTGACCATCAGCCTGCTCACCTGCAAATCCAGAAACAGGCTGTGACACTTCAGCCGCAAGAC CCCAAAGAGTTTGCGACGCATGTTCCTCCCAGCCTTGAAGCCGCGGTTGAAGGTGAGACTGGCTCTGATG GAGGTCCGGGCATAGCTGAGACACAGGGGGGAATGTCAGACACAGGTGCCTGCCCCACACCCAGCCCCCT CCTGCAAAGCTTGCTCCAAAGAGCCTCCTGCCTTCCTCCCGCTTCCTTGTCCTGCCTGGGGCATGCGCTG CAGCCCGAGGGGGCTGGGTGCTCACTCCATGGACTCCAAATGCTACATGCCATCCAGACTCTGCATGACC AAACTCCACCAGGACCTGGCTAGTGATGTTGAGTGTATCCAAACCTCGCACGGCCGTGTTTGTGCACTCA TCATCTGCCCTGATGAGATCTGCACATAACTCAGCCAAAAACACATAATAAACTGTGGAGCCCTGGCTCC CGGGCGTCCCTCGAGTGAACACAGGTGTGACTCAGGTTTTTTGTGGGAGAACACTGAGTTGGGCGTGGGG AATCTCACTGTGTTTGAATCTCAGGGATGGAAGAGCCAGGTGGCACCAGCTAAACAGGGCTCCAGTGAGT GCACGTGGCACACATGGTGTCTCCAGAGGGGCAGGATGGAGGCATCCCACCGATGTCCTCCAGGGCCTCA CCACCACTCACTGCCCATGTATGTCCATGTCCAAAGATGAACACACATGACATCCACGGCAGGCTCCTGG GGTGTGTTCTTTTACATCCAGCTTTGAACACTGCTACATTGAAATAAACGTTTTGTGCCATTAAACATTC TTCAAAAATTCTTTGAAAAATGTTTAATGGCAGAGCAAGTTTTGTGATGCATAATATCTCCTTAGCCCTG TATTTGGGCAGGTTCGTGACTTGCTGTGGCAAGTCCCCCTGCCTGGAACACTGGAAATGGTAAATAAGAC CCGTGATAATGTCTGGTCACTTCAGAAGTGGAATTACTGGGAAGACACAGGACATTGTGAGGACTTCCAT GCAAACAAGCTGCTTTCCAGAAAAGTCTTTCCAGCTTGCCTCAACCTGATGCTGGCTCTTGGCAAGCCCA GAAAAGGAGCCAGCATGAGGGATGGGGACAGGTCTCGCCATCAGTTTCACGTGCGTTTCTTTGAGGGATG GGTCTCGCTGTCAGTTTCACATGCATTTCTTTGACGCTGCTGGTAGGACCTTCCCAAGTGTGCATCAGAC GTCCATTTCTTCTTTCACAGCCATCCCCAACACGACCTTGGGCTCCGGCTCACCCTGAGCCTATGGGTCT GACTTGTGTGGGGTCCTCGGGCAGAGCAAGGGCCCCGGAGCAGGAGGCCAGGCTGCAATCATGCATGCCC TTTGCCAGCTGGGTGACCAAGGGCGGCTGCTCCCCTGGAGCCTTTCCTCCTCTACCTCTCAGGTGGTTAG GAGAACAAAGTGAGAGGATGAATGTGCAGGACCTCACAGGGCGCCTTAAATAAATCACGTGCACAAACGC TCCAGGGAATGGCCATTTTCACTGTGGCTCAGGCAAGCTGAGTTTCTCTGCAGTGAAAGCAATGCCCGTT GCCTCACTGGTTTCATCCGCCTCCCTGTGTGTCCTTCCCCAACACCAAACCAGGGAACGTTCACCTCCCT TCCCTTTGAGTCTTTTGTTTTATTTCTGTTGCTGGTGTTGTTTGCATGTGTCTCCTCTTCTACCTAGAAT CTGCTCTGGTATATGCTGTAAAGACACAACTTATTTGCTTCCAGTCAGTTTTCTCAGAAAAAAAAATTAC ACACACACTCTCTTTTCCATCAGCTGTGCCACATACCACATTAACACACGTTTCTGAGAGATAGGGCTTC CGTTTTGTTCTATTGTTCTGTCCATCAGTTCTGACCACATTCTACCATCTGAGCTGTGGTTTGGGAGACT AAAATCTGGACAAGAAAATTCCCATCTTACCACTTTTCCTTTTTCACTTTTCTTAATCATTTTGCCTGTT TTCTTCTCCCAGATGCCCTTCAAGCCTCTGCTGTATACTTCAGACACAGAGGATGTGAGTTCACCCTGAG TATGGCGAACCACTGCCTCCACTGCTGAGCTTTTAGAGCCACCTCTGCAAGCACACACTCTGACCAAGTG GCCTTTGGGAGCACAGAATATTCTGGCATTGGACCCACATCTGATGACCTGATGCCCACCCATCCTGCAC TAGCCTCTGTGGCTTTGCAATGTGTTTAGAGAGAACCCATTTTCCTGATTTGTTTGTCTGTCCTTTGTCC TTCAATAACATTCACTGATGCTGTGCCAGAGGCTGGAACCAGGGGTGCCTGTCCTAAAAAATACATTTCA TGGGGAGCAAAATAAGCAGTGGACAGTTCACAGCTGACTGGTATGGCCAGCACTGCAGAGGTGCCTGGGA GAGGCGAAGAGGTGCTGGGAGCCCAGGAAATGTGGAAATCATGCAGACAAAGCCAGTGGAGGCCAGGACC AGGTAAGGCTGTGAGAGGGAAGCAGGGACTGTGGGGAGCACAGGAGACCGGCATCCTTGTGGGGAGGGAG CTGCAACAGGGACATGCTGGGCACCATGCACAAGGGTGTCTGCACCTGCCACTCCCCCATCATGAGGGCG TCTGCACCTGCTGCTCCCCCATCACGAGGGTGTCCACACCTGCTGCTCCCCCATGAAGCAAACCCCAGGG AGCATTCTGGAAAGAGGCAAAGTCCAGATCTGGACTGTTAACTCAGAACGACAGGACCCCAGTTTAAACC TCTGGTTTAACAACCATCCACCACTTATTTCTCTTCCCATGAAGGTGTGCCTTTCAGAGGAAGGCACCCC CAGTTCCGGCCTCTAGCACAGCACCAGTAAATATTATCGAAGGACAGAATAAAAAAACACCTGTCCACTA TGGTTTTGGAATGCTGATACTTTTTTTTTTTTTTTTAAGATGAAGTCTCACTCTGTTGCCCAGGCTGGAG TGCAGTGGTGTGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAATGATTCTCCTGCCTCAGCCT CCCGCATAGCGGGGACTACAGGCGTGTGCCACCAGGCCAGGCTAATTTTTGTATTTTTTAAGTAGAAATG GAATTTCACTATGTTGGTTAGGTTGGCCTCAAACTCCTGGCCTCAAGTGATCCACCCACCTCGGCCTCCC AAAGTGCTGGGATTATAGGTGTGAGCCACCTTGCCCTGCCTGGAATGTTGATACTTTTTATTCATAAAAG AAACAGCACAGATTTCTGCATCTGTGTCCATCTTCAATTCATTTGTGTCTGAGCCTGAGACGGGGCCTTG AGCTCTCGGGCTCTGGGGAAACAAGACCCCAGAATTTTGTAGAGACCCCCCCCACACCATGGCCCTGTCC CCTGATGGGTCACACGTGATCATGAACTCATGGCATCCTGTAGACTGTGGATGAGCCTTGGAGTGTGGGG CTCACAGCGGAGAGACTCACGCCCAAAAGGGCCCTGAAGTCTCTGGGTTCGGAGAGACTCACGCCCAGCA GGGCCCCAGGGTCTCGGGTTCAGAGGGACTCATGCCCAGCAGGGCCCCTGTGTTTCGGGTTTGGAGAGAC TCACGCCCAGCAGGGCCCGGGCGTCTTGGGTTCGGATCCAGACTGCTTTCTGAAGACACCTCAGTGCACC CAGGTCTGGTGCACCATTTCCTTTTACCAAAATAGCACAGAAAACTGCTCCCGTTGTGAGCACCCTCACT CCCACAGAAAGATGCATTTCTGCTCAGCCCCAGATGGGACGAGGGGCACCCTGTGGCCTCTGACCCTTTG GGATTGGCAGTCGCCTGCCCCACACGGAAGCAGAGGTGGACGCAACGGCCCTGCAGCAGCACCTGCCCCA GCCGGGCACAGGCTCCACTTCCGGCCAGGTGCGCTCACCTGGAGTAGTCGCTCTGCACCTCCAGGGTCCG GGTATCCAGCAGCAGGCCGCACCAGGGGAATAGGCCGTGGGCCGGCATCTGAACAAAAGCCGTGCCACCC AGGGCCTCGTCTTCTACAGGGAAGTTCACCACTGTCTTCCGCAAGTTCACCACGCAGCCATACTCAGGGA CACCTCGGACCAGGGTCCTAAGGCAGAGGGGCAATGTCAGCCCCAGGATGCGGGGCCGTCACCCAGGAGG TAACCTGACACCCTTGTTAAATGCTTTGGAAAACCCCAGAGAAGTGGTGATTTGGAGCAGGGTGCTGGGC CTGGCAGGAGCTCTGAGGAGCCTGGACCCAGCCCTGCTCCAGACTTCGGGGTGCTTTCCCTGTCTCCCGG GCAGGACAGGTAGGTGAGCATGCAAGAACCTGGCCTGGACCCGGGACAGCCAGGACTCAGATGGGAGGTG CAGCCCCAGTGGCCTCTGTGATGGTCCATCTCATGTGTCCCCATGGCAACACCACAATCCCGTTATAGAC TCATCTGTGGTCCGGGGCAGACTAAAATCTGGACAAGAAATTGCCACCATCCCACCTTCTTTTAAGACGT TTCTCAACGACTTTGCCTGTTTTCTCCTAGATGCCCTGAAGGCATCTGCTGTGCTTTAGACAAAGGGGAG GGTTCTGAGTTCCTGCTCAGGCGCGGGACCTGGCTGGGCTGTGAGCTGGGCAACACCAGTCGTCAGCTTC ACGTCAAGGAGGTTCCCTCGCCGAGTCATGAGCCTCGCTCACCCAGCTCAGGGAGCCCCCCTGTGCCCGG TAGCCTCTGCTCTGGCCTGGGCATCCCCTTCCCTTCCTGCGGCCTCTGCTGTGGCCCCGGGCGTCCCCCT GCCCTTCCTGTGGCCTGGCCCTGGGACCTCGGCCAGCTGCGCAGCTCCCCTGGTGCATTCCCAGCTCCCT GTGGCCACCCCTTCCTGTTACATGGCTGCCGACTCATCAGAGACAGAGTTCTGCCCCCGGTGGGACCCCA ACATACACTCTGAGCCACCTCCCTGGCCAGCACCCTCAGGAACTTGCCACACAGAAGCAGCGTTCCCCGT CTGCTCTGTCCCCTCAGCAGCCTCAGGACTCCTGAGCCCTCAGTTGCTTGGGACCTGGGCTCCCCCCGAG TGAATCTTAGTGGATTTAAATGTGCACAGCCTGCTGTGCTCCGGGCTGCGGCACAAGGAACGCCAGGCAT ACCCCCAGCCCAGGGCGGCCCTGGAGGGTGGACCTGGAGGGTGGACTTGGAGGGCGGGTCCAAATGGGTT TTCACAAACACAGCCCAGCAAAGCACCTGAAACCACCCCTGGCGGCCACATTTTCTGAGGGTTCCCTTTA CAGCTTTCAAGGTTTCTCGTCCCTCGTCAAATCGCACTTTAAAACAAGCCCACCGGCTCTGTGGGGCGCC CTTGAGGGGGACCACATTGGACAATCCCCTGTGCTGAGGCCAGGTCCCCTGTGCCTGATTTTAGTTTGAT TCACAAAAATCAACTCTGAAACCCACTCCTAGCCATCTCCGTGGTTCAAGACAGCAGCACTCAGCAAATC CAAATTCTCCCACCGATCCCAAACAACCCCACGCAGGAACGTGACCGCAGCGAACGCTGTGGGCCAGCTC ACTCAGCAGCTCCTGCTCTCCGCAGGCTCAGGTGCACCCTGGGGAGGAGGCTGCCGCCTCGGCCCTGCAG GCCCTGTGCACAGCTCCTGGGGGTCTCACTGGGGCCCCAGGAGCCGCCACTCTTGACTTTCCAAAGAGCA GCAGGAGCCAGGTCACCGCCTGCACTCACCACGTGTGTAACCTGGGTGCGTCTCTGCAGGACCAGGGCCT GCACGGTACCCACTCCCTCCCGAAGGTGCCCCTGCGCCCCCAGGCCTGGGTGCACGGCCAAGCGCCTCTG CTCTTGCGGATCCAGCACCGGCAGAGAGAGAGGACTTGGCAGAGACAACGCTGCGGTGCCAGGGGCAGGA CACGGGGGGCTCAACTGCAAAGCCCACAGGCTGTGGAGGTCCCCACAGACACACGGCACGGGCCTCACCT GAGGAAGGTTTTCGCGTGGGTGAGGTGAGGTGTCACCAACAAGAAATCATCCACCAAACGCAGGAGCAGC CTAAAATAAGGGAAAATACACAGCAAGGTTAACTTTACACTTTTTACGTAGTATCTGTCTACGAGGGACT GAATGTCAAACAATTTACACAGCCATAAATAAAGTAACATTCTCCAAAGCGGTTAAATGAAAAACTTAAA TTTCTTTCCAACAGACGAGCTCTCTACAGTTAACTGCTACAGCAATTCCTCATTCATTATAAGTACTCAG TGTTTACCATCAGCTTGTGCAATTCTGTGCCAGCTGAAGACGAACGAAGGCCATCAGGCGCGGCCCCACT TCTCAGACTCTTAGGGAAAAATAACTGAAGACGGTAAGAAAGCTGGGGCTGGGAACCTCGCCCCCTCTGA GCCACGTGGTGCCCTTTACCAGCATGGCAGCTGTGGTCCTCAGCATGATCCGAGACCCAGATCCTATCCA CAGGAAGCTGGGCATGGTGCACTGTGTGACCCTCAGGCCCAAGCCCAGCGCCCCATGACCATGGGCCAGA GGTATCCTGTCCCAGAGGGCTGACCAGTGTGCCGCCAGCTCGAGGACACTTTCCTCCAAATCCCAGAGCA AGTTGTGTGTACAAGAAATTTTTGTTTCTGTTACATAAACTTATTTCAATCTAGAACTTGAACCTTAATG AAGAAGAACCTTGATCCACTGTACATGCTATAATTGGAGCTAGAGTTTCAAAAGATGCACAGGAAAAACC CGGAGTCTTCGAGAGAAATGGCTGTGTGGCCTGCAGGCTTCCTGACGCATCCTTCACTAACTGTCTGCTT GTTCAGTGATACTATTTTCATAAAAAAATAACTGCTGTCCACATCCTCTCCAGCACCAGAACACTTTTAC ACTGTTGGTGGGAGTGTAAACTAGTTCAACCATTGTGGAAGACAGTGTGGTGATTCCTCAAGGATCTAGA ACTAGAAATACCATTTGACCCAGCCATCCCATTACTGGGTATATACCCAAAGGATTATAAATCATGCTGC TATAAAGACACATGCACACGTATGTTTATTGCGGCACTATTCACAGTAGCAAAGACTTGCAACCAACCCA AATGTCCATCGATGATAGACTGGATTAAGAAAATGTGGCACATATACACCACGGAATACTATGCAGTCAT AAAAAAGGATGAGTTCATGTCCTTTGTAGGGACATGGACGAAGCTGGAAACCATCACTCTGAGCAAACTA TTGCAAGGAAAGAAAACCAAACACCACATGTTCTCACTCACAGGTGGGAACTGAACAATGAGAACACTTG GACACAGGGTGGGGAACATCACACACCAGGGCCTGTCATGGGATGGGGGGAGTGGGGAGGGATAGCATTA GGAGATATACCTAATGTAAATGATGAGTTAATGGGTGCAGCACACCAACATGGCACATGTATACATATGT AACTAACCTGCACGTCGTGCACATGTACCCTAGAACTTAAAGTATTAAAAAAAAAAAAGTAACTGCTGTC AATAAAAGCCAGCTGAGTTGAACCACATTAGGTTGGCACGATATTTAGGTGTGTGCGTCCTTGGGTGTAG ACCCCATGCAAGTGGGATGGGCAATGGGCTGAAGAGGCGCCCAGTCCAGGCCACCTGTCGAGGGCCTGCT GGGAGATGTGGGGCCTCAGGCTGCACCAGCCCCATCTCCCCAAGGACCCTAACGGAACCTGGGTGACGTG ACAGAAGCTGGTGTGCTTCCTCGGTGTTGAATTCACATGCTCATCATGCAGGGCAGCGGCCCTCCCGCCT GCTGAGCCCTGAGGCCTCTGGACATGGCCGCTGGACAGAGCCTGCGTGGAGCCCGCAGTCCTCAGGCTGT GCAACCCCTCCCGTGCGGCTTCATACCAAGAAGGGGCTGCAACCTTGTCTGGTTCCTCAAGACAGAGCAG TCATGGTCTCCAGAGCACCAGGAATATTAACACTGAATGCATCAAAAGCAAATCAACCCCCACCCAAGCC CCCCTGGGGAAGAGGAGGCCTCACCCGTCCCGCCGAATCCCCGCAAACAGCTTGTTCTCCATGTCGCCGT AGCACAGGCTGCAGAGCAGCGTGGAGAGGATGGAGCCCTGCGGGATCCCCTGGCACTGGACGTAGGACCT GGGGCGGGAAGACACAGGTGAGAGACGGGCAGGGCATGTGCTGGACATGCGTACACTCAAACCGAGCCAC ACACAGACACAGAACCTCATACACACAAACGACACGTCTACCATTCAGCCGGCAAACACCTCAGAAACAT ACCAGATGAGACCTCTGAACAAACAATCCCTGCTCCCCACTCTCACCATGCACTGGGGCGGCTGAAACAG ATCCAGCCACAGGTGTGACCACATCCTTGCTCTGAATCATCAAGGTTTTCTTTCATTAAGGTTTCTTAAA TCTTAGAGTTTATTCACAGAACCAGACACTTGACCCGGAATGAATGCTTAACCGGACTCCTTTTTTTTTT TTCAAGGAATTTGTCCACGGTGAAAGACTCATGACCCTACATGTAGCCGCTGCGCGCCAACGGATACAAC CTTGCCCCTAGTTTCAGCATGACCAACGAGAAGCAGAAACTCTCCAAACAAGGATGCCAAGGGTGCGTTT TCAGACAAACAGTGAGAGCAGAATAGCCCCGTGGAACCTAAAGGTGCACACAGAAGGCATGGCTGCCACG CGACCCTCAGCCATCCCCAGAGCCCACAGGACGCCACTCCTGTTGCTAAGAGACGCTTGCAGCCTACTGC AAAAACAAGACCTGTTATTTTCGGGAAGCGCTATAGGTGGTCACCTTAAAAAGAGGCTTTCCGGCTGGGC GTGATGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCAGGAGT TCGAGACCAGCCTGGCCAACATGGCAAAAACCCCTCTCTACTAAAAATACAAAAATTAGCCAGGCGCAGG GGGTGGGTGCCTGTAATCTCAGCTGCTCGGGAGGCTGAGGCAGGAGAAATGCTGGAACCCGGGAGGCGGA GGTTGCAGTGAGTTGAGATCGCGCCACTGCACTCAAGCCCAGGCAGACAACAGTGACGTTCCGTCTCAAA AAAAAAAAAAGAAAGAAAAGAAAAGAGGCTTTCCTTGCTGGTGCAGATATCACAGTGATGGGCAAGAGGA CTGCACTTTTTGCACAGAAGCACACGCACCAACTCTAGGAGTCCGGCCAGCCCAGCGAGTCAACGCAAGC AGATACGCCCCTGTGAGCACATGGGATGGGAAACTCTCTCTGTTCTTAGTTTTTGGGGCAACAGGTTTTG AAGACGTTTTTATTCAGAGGCCAAACTGGACCACGATGGGGACTAGAGCTTCGGGCCTGTCCGTGTCCTA GGGACAGGACAGACACAGTCACCTCCTGTCTGTCAGGGCATGAGGACGCAGTCATCACCTCACATTCCCC AAAGCCCTGCCACACGTGGACGGTACGTGACTTGATCCATCTTAATAAAATTCACGACCACGAAGGAGGC CCGTGGTGGCTTCTCTGGGGAGGTGACTTTGTCAGCGAATTCTGTGGGCCTGGGGGCCGCTTACACACAT GTGCACACGTGTCCCTCGGCCAAAATTCACTCTGCTGCCATGTGCAATTTGTGTTTTTCCAGAACGTGTG TACTACTTAATATTTCTAATTATACTTTAATAAATATTATAATTGCTGATACCATTAGTGATTACTTATA ATGCAATAATTAATAGTTATATTTTTAAATAAAAGCTTCCGAAGCTGTGCACAGTCCTTTATCCGCTGGA GACGATCCCAGAGAGAGGCCTCCACGTTCCACCTGACTGCGGATGACCTTGCTGATGACCTTGAGTGTGC ACGAATTTCCTCCGTGCTACCACTCTCCCCAGGCACACACAGGGTCGCAGGCAGATGCCTGCCGGGAGGT GTGTGGTTTTACTTAAAATCCAGAGGACGTGATGTGGCACCAGGCACTGTGGCTCTACCACCGTGAGTGT GGCTCACCCAGTGGCTGTGTGACGGCAGCTCTCCCAGGCCGCCTGCCCCATGGCCACCACAGGCCCCCCG AGAGGAGCAAACTACACGGTCAACCCCGCACTTTCCAGATGGGAAATCTAGTCACAGAGAGAAGAGCCCG CGCCCTCGCGGGGGTCACACGACAGGGACAGGAATGAGAATCGGATAAAATCCTTTTGTATCGGGAGAGA GAGATACAAGCGTGTGAGAGCCGGGTGTCCAGCGTCAGTAGTAACTTGGAGCTGACAAGCTGCAGGCTCA AACGCTCGGCGCACACCTGACCCAGACACACCCCCCGCCCCTCGTCCTCCACGCAGGAGCAACTCCACAC CCCGCTTGCCATTTCCAGGCCTCGTGTGGCACCTGCTCCGCTCCGGCTGCCGCAAGCCGAGCCATGTTTC CGGGGCCTCGGGAGCCTGCAGCCCAGGAGCCGGAGGGGGCGGGGGCCAGAAAAGGAGACTCTGGTGGCCC CGGGCAGAAGGGCAGTGGGGAAGGGGCAGGAGAGAGGTGAGCAGAAGCCCTGCCAGCCCGCCCAGCCACC CGCAGGGCAATGGCACCTGGCCACCTGACTCACTTGCCCCTGATGCGCACGGCGTGGTGGCACATGAAGC GTAGGAAGACGTCGAAGAGGCCACTGCTGGCCTCATTCAGGGAGGAGCTCTGCGAAAGCAGACGGGAGAC ACATGGGAGTGAGCCGGTGGGTGCTGAGACAGGCAGGACCACGTGGCCAAGACCCTCCGTCCCTTTTGGG GTCAGTGTTTGTGATGAAGTGCGGGGCTGGGCTGGAATGCAGGGCCATCGTGGGCTGGCCGGGCCGAGTC TCTGCAGACACACATGGGCTTAGGCAGAGTGTGTGACACAGAATGTCTCCTCTGGGCCACCTGTGGGTCC AGCTGGGCTCACACCCACACAGCCCACCGTGGCCCGGATGGCATATGTGATCCAGGAGTTGCTGCCCAGC TGCCGGGCACAGGGTCTGGGTCCCAGCAGCCCAGGCCACCTCCACCCCCACCCTGGGAGCCAAGGAAATT CGCCCAGAGGTCTCTGAGCCTCATGCGGTGGACACGACTGTCCCCTAGAGCCGAGCAAGTGCTAACAGGC ATCTGCAAAGAGCCACAGGGCCACGTGGACAGACCACATCTGCAAAGGGCCACAGGGCCACGTGGACAGA CCCAGCACTGAGAGGCCCGCTCAGCGGGGCGTGGCTCAAACACGGCCCGTCCTCCTAAGAAGGGGGACAC GTTTCCTTTGGCCTCAGACCCAGCACTGAGGGGCCAGCTGGGCAGGACACGGCTCAAACATGGCCTGCCC TCCTAAAGGAGGGGGACACCTTTCCTTTGGCCTCAAGATCAAAACTGGCAGAGAAGACATTTAGCAAATC ATGAACAAAGGCACTGCGGAACTGGAGAGAGGCCGCGCAGTCAAACGTGAGCAGGTGCCTGAATGCAGCA GCTGTCGCAGCCTGGCATGGCCCAGCTCAGATTTCGCCAAGGCACACAGCTCATCATGCCCCCATCACAG CTCATTCCCCCCACTGCCCCCCAGGGCCAACAGTCTGTCCGGTCATGAGCCCAGTGATTGCCCAGGGGAG GACCCACTGCTGGGAGTCCGTGCCCAACCCTGCAGGGCAGTGCCCAGACCTGCTCGATGACGACGGCATC CCTCAGCGGGCTGGTCTCCTGCAGGTGAGCCACGAACTGTCGCATGTACGGCTGGAGGTCTGTCAAGGTA GAGACCTGCCGGCAGAGGAGAGGGCATGAGCCACAAATGTGGCCTGCCCCGGCCAGAGCTGGGCACTTGT TTCTTCCGATCAGGACGTGTGGACCTGCGGCCAAGCCCGATGGCGGGATGAAGCCCAGAGAGCGCCTGGG AAGCTTCTGTTTGGGAAACGGGGGCCGGGGGGCCGAGGACGCAAAGTAGCTACAGACACACCTGGGACTC CACCTGCAGCTACCACACATCAGACCCCTGTGACCGATCACCATCCACAGTCACCACATCAGACCCCACG ACCGCCATCCACAGTCACCACATCAGACCCTACGACCGCCATCCACAGTCACCACATCAGACCCCACGAC CGCCATCCACAGTCACCACACATCAGACCCCACGACCGCCATCCACAGTCACCACACATCAGACCCCACG ACCGCCATCCACAGTCACCACACATCAGACCCCACGACCGCCATCCACAGTCACCACACATCAGACCCCA CGACCGCCATCCACAGTCACCACATCAGACCCCACGACCGCCATCCACAGTCACCACACATCAGACCCCA CGACCGCCATCCACAGTCACCACATCAGACCCCACGACCGCCATCCACAGTCACCACACATCAGACCCCA CGACCGCCATCCACAGTCACCACACATCAGACCCCTGTGACCGATCGCCATCCAGTCACCACACATCAGA CCCCCGGGACCAACCGCCATCCACAGTCACCACACATCAGACCCCACGACCGCCATCCACAGTCACCACA CATCAGACCCCTGTGACCGATCACCATCCACAGTCACCACACATCAGACCCCACAACCGCCATCCACAGT CACCACACATCAGACCCCACGACCGCCATCCACAGTCACCACATCAGACCCCACGACCGCCATCCACAGT CACCACACATCAGACCCCACGACCGCCATCCACAGTCACCACACATCAGACCCCACGACCGCCATCCACA GTCACCACACATCAGACCCCACGACCGCCATCCACAGTCACCACATCAGACCCCACGACCGCCATCCACA GTCACCACACATCAGACCCCACGACCGCCATCCACAGTCACCACATCAGACCCCACGACCGCCATCCACA GTCACCACACATCAGACCCCACGACCGCCATCCACAGTCACCACACATCAGACCCCTGTGACCGATCGCC ATCCACAGTCACCACACATCAGACCCCCGGGACCAACCGCCATCCACAGTCACCACACATCAGACCCCAC GACCGCCATCCACAGTCACCACATCAGACCCCACGACCGCCATCCACAGTCACCACATCAGACCCCACGA CCGCCATCCACAGTCACCACACATCAGACCCCCGGGACCAACCGCCATCCACAGTCACCACACATCAGAC CCCACGACCGCCATCCACAGTCACCACATCAGACCCCACGACCGCCATCCACAGTCACCACATCAGACCC CACGACCGCCATCCACAGTCACCACACATCAGACCCCTGTGACCAACCGCCATCCACAGTCACCACACAT CAGACCCCCGTGACCGACTGCCATCCACAGTCACGTGGCACAAGTGGCACTCGAGCTCCCGGGCCTCTCC AGCCCAGTGCTGGAGGGATTGCAGGGATGCAGGTGCAGCCACAGCACAGGCAGGAGAAGAGTCTGAAGAC GCGGGAGAGAGACCGGCACCCCCACCTCCTATTCTGCAGACTCCCCCAGGACGCTTGTCATTTACTACGG GACCTGCTAAGCCCCTGCGTCCCCAAGACAGGATGTGAGCAGGCACGTGACACACACTAACACGGACACA GGAGGCCTCGAGCTTGTGAGGCATCAAAAGACGCGCACGGTGACTCTGTGCTTCAGCATGTTCCCCAGCC CCCAGGAGCTGGCGGCAGGGCCGTGGGCTAAAACCACATCGAGTACGATTCAACCCTGAGAACCAACCTG GAAGGCAGTAACAGGAAGGTACATGGGGCCTGCACCCTTCCCAACCCAGGAGCAGGCAACACGCCCACAA ATAGCCCATGGGTCTGAGGTCGGCGGAAAGCATCACAGAAATCCGTAATTATTCTGGACTCAACACAGAA AAGCCAATATATCAACACTGACGAGAGGCTGCTGAAGCAGGTCTTTAGCACAGGGTCCCCAACCATTGTG GTACCAGGGACTGGTTTCGTGGAAGACGATTTTTCCACAGGACAGCAGTGGGGAAGGGGATGGTTTTGGG AGCAAACGGTTCCACCTCAGATCATCAGGCATTAGATTCCCATAAGGAGCACAGAATCTAGACCCCTCTC ACGCACAGTTCTCAGTAGGGTGTGTGCGCCTCTGAGCACCGCATGCCACTGCTGATCTGAGAGGGGCGGG GCTCAGGCGGGAACGCTGGCTCCCCACACCCCACCTAGCCTCCCGCTGTGCGCCGGGTTCCTAACAGGCC CCAGACCGGTGCCACTCCACAGCCAGGGGCCTCGGGATCCCTGCTTTAGAGGGAAAACGGCAACTTCAGA TGCTTGTTTAGAAAAGAAAGTTCAAACATCCATAATCGAAACTTTTCCTTCAAGGAGCCGGAAAAACAAC AATAAACAAAGCCTAAAGGAAATGGAAGGAGGCCATCGATAAACAGCAGACACCAATTACGCAGGAAACA GCCGGGAAATCAGCACACGTGAAACTCTTCTGTGAAGAGAGTCATGAAATGGAAAGACCCCTAGCGAGAC CTGGAGAAGGAAAACGGAGGTTGTCAGCACCAAGGCTGCAGGCAGCTATCGCTGCAGATCTCACGGAAGC TGCAGGAAGCGAGTCTCGGCCGGGCGCGGCGGTTCACACCTGTCATCCCAGCACTTTGGGAGGCCGAGGT GGGAGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGAGAAACCTCGTCTCTACTAAA ATTACAAAAATTAGTCAGCATGGTGGTGGGCGCCTATAATTCCAGCTACTTGGGAGGCTGAGGCAAGAGA ATTGCTTGAACTCAGGAAGCACAGGTTGCAGTGAGCCAAGATCACGCCAAACCACTCCAGCCTGGGCAAA AAAGAGCGAGACTCTGTTATCAAAAAAAAAAAAAAAGAAAGAAAAAAAGAAAGAAAGCAAGCCTCCAACT CGCAGGGGAATTCCAAGGACGGAGCGTAGCCAGGGCCACATCCAGGCCAATGAACACAAGGAGGCCTGGA AGCCCTGCCCACCGGCCACACACCACAGCAGGCACCACACGACCCCAGAGTGGAAGAAACAGAACAGGGA GCCCAGGGGAGGCCTCCACACCCCTGACTTACTATAAACCCGACCATAGTTCAAAGGAAGATATGGTCTC CTCAATAAAGCTGTTGGAGCACCTGCAGACCCACTACAGGAAGAAAGCTCGCCTTGAACTCTGTGTTACC CCACTCATAAAAACCAATCCCACAGATCCCCACCTATCCCACACATGAAAACCAATCCCACAGATCTCCA CCTACCCCACACATGAAAACCAACTCCACAGATCCCCACCTACCCCACACATGAAAACCAATCCCACAGA TCCCCACCTACCCCACACATGAAAACCAATCCCACAGATCCCCACCTACCCCACACATGAAAACCAATCC CACAGATCTCCACCTACCCTACACATGAAAACCAACTCCACAGATCCCCACCTACCCCCACACATAAAAA CCAACTCCACAGATCCCCACCTACCCCACACATGAAAACCAATCCCACAGATCCCCACCTACCCCACACA TGAAAACCAATCCCACAGATCCCCACCTACCCCACACATGAAAACCAATCCCACAGATCCCCACCTACCC CACGGATGAAAACCAATTCACAGATCCCCACCTACCCCACACATAAAAACCAATCCCACAGGTCCCCACC TACCCCACACATAGAAACCAATCCCACAGATCCCCACCTACCCCACGGATGAAAACCAATTCACAGATCT CCACCTACACCACACATGAAAACCAACTCCACAGATCCCCACCTATCCCACACATGAAAACCAATCCCAC AGATCCCCACCTACCCCACGGATGAAAACCAATTCACAGATCCCCACCTACCCCACGCATAAAAACCAAT CCCACAGATCCCCACCTACCCCACGGATGAAAACCAATTCACATATCCCCACCTACCCCACACATAAAAA CCAATCCCACAGATCCCCACCTACCCCACACAAGAAAACCAATCCCACAGATCCCCACCTACCCCGCACA TGAAAACCAATCCCACCTACCCCACACATAAAAACCAATCCCACAGATCCCCACCTACCCCACGGATGAA AACCAATTCACAGATCTCCACCTACACCACACATGAAAACCAATCCCACAGATCCCCACCTACCCCACAC ATGAAAACCAATTCCACCAATCCCCACCCAGGTTTGCAAGCTGACACAGTAAAGACTGTTCTAAAAGGAG GCGCAGAAGCAACGTCACCACAACCTCAATACCTTGAGTTCCTGCAGAGAACACAAACAGCTTTAGCCAC AAACAGCTGATAAAGTGGACTGCGTTACTGGACTGTGTTAGTGGACTGCGATAGAAGTACAATCTTCCAG TCCTCAAAAGGCTTGACTTGAGAGCACAAAAGCAAGACACACACGGCACAGAGATTCACAGTGCACGCAT GTGATGCCACACTTGCAGCAGAACACACAAAGAGCTCCTGCAAGCCGATGATGGCAGGCAGGCGCCCCAT ACAGAGCGGGGCAGGACGGACAGCCACCTCCCGCAAGAGCCCCGGGGCGGCCAGCACGGGAACACTGTGG GCACGTGGGCATCAAGAGAGCCCCCTGCACAATCCCACGAGGCGGCTTCGACACCTTCAGGCCAGCGGCC ACCGGAGGCATCGCCCTCACAAGCAGCCAGCCGGGGTGTCACTGTCACCCCCCTGGAAACTCCCACAACA TCCCTAAAGCACGTCTGTGACCCAGCAACCCCACCCCTGGAATTCACCCAGAGGCGAGGGCCTCTGACCC CTGGGACACTCCCAGAACCCAGCAGGCTCACAGCAGGCGCAGCCGTGCAGTCCGCACCCAGGAGCCTCCA CAGCAGCGGGAAGGATACATCCACGTGGCGAGTTCCACAACGGATGCCATTCATGGACAGAACGCACAGC TGAGGCGTTCAGCATAGCTGAGGCTCGAACCCCAAAACCCACCTCCTGCCTGATCTCACTCACATGGAGA CCGGGAGAGGGAGACCATGGAGGTCGAGGTCGGAACGAGGGTCACGGTGGGGGCGGTAGCTTCCGCTGCA GCGGGGATGTGGGGGGGGGTCTCCTGGGCTCTGGTGACTTTCTACACCCGGGCACAGGTGGGCGGTGGGG ACGGGGGGGTCTCCTGGGCTCTAGTGACTTTCTACACCTGGGCACAGGTGGTGGCCATCAGCTTTCCATG AGGGTAAAATTCTGCTGAGATTTGCAAGTAGCTGCGATAGCTCAAGAAGTCAGAGAAAGAGGTCCTTGTG GGTTTCCACATGTGCCTCTCCCCAGACCGAAGCTCCAGGGATACTTCTTCACCTCTGCACCCCGGCCTGG CACGACTTTGAGGGCTTACCCCTCCAGCGTGCTCATGACCACTGGGTGGGAACCCAAGCCCAGGGCCCCT TTCACCCCTGCCGAGCCCCAAGGCCCCCGGCCGCTCTGGGAGGAGTGTGTCCCGGGGAGCGAGGCCTGAA TCAGCCTTCCTATATCTCATGGAGCCGGCATAGGCCAGACTGGGGTCCTGGGGGTGCCAGGGGTCCAGGA AGGTACCACCAGCATCCCTACTCTCCTCTCAAACCTGGCTTACAGTCTCCAAGGCCCAGCCCTGTGACAG GACAGGGGCACCCATGCTAGAAGTGAGGACCCTGAATGTGGAGCTCCCCAAACCAGCACCCGAGAGCGTG AGGACAATGGTGCGGACCATGCCTGGAGGAGGAAGGAGTAAGGCCAAGGGGCCACACACACCCATGCCAT AGACACGCATATGTCACGGACACATGCACACACACACACCACAAATAGGCACATCACAGACATGCAGCAC ACAGCATGAACATGCACGTGTCACAGACACACACACATGCACACCACAGGCACACACACCATGGACACAC ACGTGCCACACACACACACACCACAAATATGCACGCCACAGATACATGCACCACGACACACACGTGCCAC ACACGCATATCACAGATGTGTAAATCATGGAAGTACCTCCACCACAGAAACGCATCACAGACACGACTGC ATTCTAGACACATTCATATCCCAGAGACACACATCCTGGACACGACTATCACACGTGAACCTTACGTGGC TCTTGAAGGCCTTGCGGACGTGCCCATGGGCGGCCTTCTGGACCACGGCATACCGACGCACGCAGTACGT GTTCTGGGGTTTGATGATGCTGGCGATGACCTCCGTGAGCCTGTCCTGGGGGATGGTGTCGTACGCGCCC GTCACATCCACCTGTGTGAGTGGAGGCGAGGAGACTGACAGTGGCCACGCAGAAACTCAGACATCACCTC TGCCCTCAGGGCCTGGCCTGGCGGTGTCCCCCACTCTCTCTCTGACCCCCACCACTCCAGACCCCAAGGG CAGGGCGGGCTGTGTCCCCTCTCTGAGCCTCAGGACAGGAGACCCCTGGCTCAGGACTGGGGTGCAAGGC ACCGGGGCCTGGTGGCTGAGCCGTTGCGGTTCCTTCTCTGACGGAAACTGGAATCCAGTGGGACCCTCCT TGGGAATAGGAGCCCGGGCAGTCAGGGTGCACAGTCGGCCCCATGTGCTGCAGGAAAGGCTGAAGGCCTC CACCCTAGGTGCCAGGTGTGTCCTCAACAGTGACAGGGTCACCTGCACTCCCTGCGGCCCACCCAGGAGT ACCTCCTCCACCCAACATGAGGTGCCAATCAGGCAGCCACTCCCAAGGTCCAGCAGGGCTGCTCACGGGG GTCCCCGGCACCCACCTTGACAAAGTACAGCTCAGGCGGCGGGTCCTGGGCCCGCACACGCAGCACGAAG GTGCGCCAGGCCCTGTGGATATCGTCCAGGCCCAGCACAGAGGCGCCCAGGAGGCCGGGGCGCCGCGCCC GCTCGTAGTTGAGCACGCTGAACAGTGCCTTCACCCTCGAGGTGAGACGCTCGGCCTGGCGGGGACAGCA TGGGAGACAGTCAGGAAAGTGGATCCGGCCAAGTGCCCACCCCACCATAGGGACCCAGGGGAGAAGCAGC CCCTCCCCAGTGTCCCCAGCCACCCAGACCCGGGACCTAGAACCCCTCCCAGCTTCCTCAGACCCTGTTT GAAACGGGTTCCTGGCCGCATGTGTGTTGCACACGGGATCCTCATGCCACACCTCTGTCCACCTCACCCC ACACTCTCCTCAGATGACGGGGTCACCGCAGCCACCGCAGCCACAGGGGTGGGGTGCAGGAGCCGTGGGG CAAGGTCCAGGATCCTCAGAGCCCGGTGGGCTCCTGGCAGTCGTGGCCTGGTCCCCGGGCCCCGTAAGCG GAAGCGCACGGAGGCTGCGCACCACAGCAGGACACGGATCCAGGACCTCGGGCCGTGCTGCATCCAGGCC CTGGCCCGGCTGCTTCTTGTGGTCCTCAGAGCCTGTCCCTGCCCCAGGAGCTCCCCCTACACCCCCACGC TGCTTTTCTGGAGGCACCGGCACCTCGGCCACCTCACTGTGCGCACAAATGGGTTGGCGCCGTGCCATGG CCCTGGCTGTGTCCCGTGGCCCCTCCTCCGGGCCCTTCATCTAAGCTGATACCAAATGTGGGGCTCAAAC GCACTTCTGTTTAAAAAGGAAGTTAAACCAAAGCACAGCCACCCTCTTTTCTCTGCGGAACGTTCTGGCT CCCACGACGTAGTCCATGTTCACAATCGGCCGCAGCCCGTCAGGCTTGGGGATGAAGCGGAGTCTGGACG TCAGCAGGGCGGGCCTGGCTTCCCGATGCTGCCTGACCTCTGCTTCCGACAGCTCCCGCAGCTGCACCCT CTTCAAGTGCTGTCTGCAATAGAGAGCCCCTCAGGAGGCTTGCTCAGCCAGACAACAGACTAGGGGGAAG CTCACGGGAAGCCACAAGCCCCCACCGACTCAGTGAGGGCTCAGGGCACCCACGGCAGCACACGCTGAAG GCCATGCCCGGGGCCACGTCCACCCATGCCAGCCAGACGCCTCTGAGAGCCCCTCTACTTGCAGGGCACC TGGACACCTGGTCCTATAGTCAACCCTGGGGACGCCCAGTCCGGCGGTCAACCCCCAGGGTGACTGTCCC ACCATCAGCACCAGGGAGCCTGGTCCCAGGCTGCATCTGGGGCCACGTGAACCCATGCCCCTCCACACAG GATGCCTGTCCCTCTGGTACAGCCACTGGGGTAGCCCAAGGCTGGCCCCAGGCAGGACCCCCAGGTAGAA AGAGCCACATCCCTTCAGATGGAGAGGGCGGGAGAGGCTGCTCAGGGCAGCTCAGCCAAGGAGCAGAATC AGCTCTCATGAGCCCACCAGTCTCCTGACACCTCTGCCCTTTGGCCTTTTCCCCCAAAACCACCCATGGG GGCACGGGGGCTGGAGCGGCCACACCTGGACCTGGGCATCTGTGGCTGACAGCCTGGCACTCCGTGGACA CTGGGGCCGCGGGTGCTCCGGAGCTGGTGCCCTGACCGCAGGCCGCAGGCCCAGCAGAGTAGAAAAGGCA CGGTACCCTGTCCAGGGAGGAGGGGCCTCCAAGGCCCCCCAGGCAGAACAACAGTCCCAGTAGTGACAAG GAGCATCTTGGGGACCACCACGTCTGTCTGCTCCTTCCGGTCACCCCAATTAAATTCTTTCCAAAATACT GGTCAAATGACCATGTTGGGTCGCACACCATTAAATACGTGTAAAGTCTAAGTAAGGTGCATTGTGTATT AACTTGTTCCCACAGGGAAAGCCCTGACCCTCCCCCAGATGCAAGGAAATGGCCCCAGCACCACGTCGGG GTCCCCAGCCCAGAGGCTGTGTTACCTCTGACGAGGTCTGCTGCCAGCTCCCTCTGCAGACATCCTGATT TGGGGCATGGGGTGTCACAAGGCCCCCCAGGGACTCGAGTGTGCAGGGGAGCTGGGGAAGCCCTGATCTT CTGACTAAAGCCCTCCACAGTCAGCCTGGGCGGGACACGGAGAAGCTAATACCATGGCCTGGGCTCAGCC AGGCTGGCATCTCCCAGACCAGCGCTCCCGTCCCTCACTGATGCAAATCCAGCTTGAATCTGTCACAATC TCACACTCTCATCAGCCGAACATTGCAGACAAAATCTCACAGCCATTCAAATGCAGCCACCTAGAAGTTA GCTCATGGTGGAACTCTCCTATCCCCAGGTGCTCCCTGCACAGGTGCTCCCTGCAGTGAGTCGCCAAGTG GGTGGGATTTTATCCTCTCATGACCTAAATCCAATAGATTGAAGATTCATACAGAACAGCATGAATTAAA AGAGAATCGGGGGCTGGGCACGGTGGCTTAGCCTGTAAACCCAGCACTTTGGGAGGCCAAGGTGGGTGGA TCACCTGAGGTCATGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTCCTAAAAGTACAA AAATTAGCCAGGCGTGGTGGCAGGTGCCTGTAATCCCAGCTACTTAGGAGGCTGAGGCTGGTGAATCGCT TAAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTATGCCACTGCACTCCAGCCTGGGCAACAGAGTG AGACTCCATCTCAAAAAAGAAAAAAAAAAGAGAGAGAGAATCAGACCCACATCCCAGGGAAAGGCAAGGA GGCTAGTGGTAGTGTTTCCATCTAATTTAAATCCCTTCTGCTTTACAAACCCTAGAGACCACTTGGCACA AACTCCTGATTTTACAAGTAAGAGAACGTGAGCTCCAGGCAGTCAGAGCCTTGCACAGAATCCACTTGGA CCAGGCCTGTGACGGGGCCCCTGGCTCCCAGCCCAGAGCTGCACAGCCAGGGAAGCACAGGCAAGTGGAG ACAGGCGCATGCTGAGGCCGGGCTGGTGTTCCAGGACTTCGAGAAGCAGAGGCCTGGCGTGGGGATACAG TACCTGATTCCAATGCTTTGCAACTTGCTCCAGACACTCTTCCGGTAGAAAAAGAGCCTGTTCTTTTGAA ACGTGGTCTCCGTGACATAAAAGAAAGACCTGAGCAGCTCGACGACGTACACACTCATCAGCCAGTGCAG GAACTTGGCCAGGATCTCCTCACGCAGACGGTGCTCTGCGGCCGGAACACAGCCAACCCCTTAAACGAGA AGGACATGCCACATCCAGATCACCGAGGGCCTGGTGACCTCACCCCGGACCTGCACCATCCGGACACCGC ACATCCAGCTCACCAAGGGCCTGGCGACCTCACCCCAGACCTGCACCATCCGGACACGGCACATCCAGCC CACCAAGGGCCTGGCGACCTCACCCTGGACCTGCACCATTCGGACACGGGGACACCGCATATCCAGCTCA CCGAGGGCCTGGCGAACTCACCCCGGACCTGCAGCATCCAGACACCACACATCCAGCTCACCGCAGGGCC TGGCGAACTCACCCCGGACCTGCACCATCCAGACAACACACATACAGCCCACCGCAGGGCCTGGCGACCT CACTCCGGACCTGCACCATCCGTACACTGCACATCCAGCTCACCGCAGGGCCTGGCGACCTCACGCCAGA CCTGCACCATCCGGATACAGCACATCCAGCTCACCGCAGGGCCTGGCGACCTCACCCCGGACCTGCACCA TCCGGATACAGCACATCCAGCTCACAGCAGGGCCTGGCGACCTCACCCCAGACCTGCACCATCCGGACAC CACACATCCAGCTAACCGCAGGGCCTGGTGACCTCACCCCGGACCTGCACCATCCGACACCGCATATCCA GCTAACCGCAGGGCCTGGCGACCTCACGCCAGACCTGCACCATCCGGATACAGCACATCCAGCTCACTGC AGGGCCTGGCGACCTCACCCCGGACCTGCACCATCTGGATACAGCACATCCAGCTCACAGCAGGGCCTGG CGACCTCACCCCGGACCTGCACCATCCAGACACCGCACATCCAGCTAACCGCAGGGCCTGGTGACCTCAC CCCGGACCTGCACCATCCGGACACCGCATATCCAGCTAACCGCAGGGCCTGGCGACCTCACCCCGGACCT GCACCATCCGGACACCCCACATCCAGCTCACCGAAGGCCTTGGCTACCTCACCCCGGACCTGCACCATCC AGACACCGCACATCCAGCTCACAGCAGGGCCTGGCGACCTCACGCCGGACCTGCACCATCCGGACACCAC ACATCCAGCCCACCAAGGGCCTGGCGACCTCACCCCAGACATGCACCATGCAGACACCGCACATCCAGCT CACCAAAGGCCTGGCGACCTCACCCCAGACCTGCACCATCCGGACACGGCACATCCAGCCCACCAAGGGC CTAGCGACCTCACCCTGGACCTGCACCATCCGGACACGGGGACACCGCACATCCAGCTCACCGAGGGCCT GGCGAACTCACCCCGGACCTGCAGCAACCGGACACTGCACAACCAGCTCACCGCAGGGCCTGGTGACCTC ACCCCAGACCTGCACCATCCGGATACAGCACATCCAGCTCACAGCAGGGCCTGGCGACCTCACCCCGGAC CTGCACCATCCGGATACAGCACATCCAGCTCACAGCAGGGCCTGGCAACCTCACCCCGGACCTGCATCAT CCGGACTCCATACCTCCAGCTCACCGAGGGCCTGGCGACCACACCCCAGACCTGCACCATCCAGACGCCG CACATCCAGCTCACAGCAGGGCCTGGCGACCTCACCCCGGACCTGCATCATCCGGACTCCATACCTCCAG CTCACCGAGGGCCTGGCGACCACACCCCAGACCTGCACCATCCAGACGCCGCACATCCAGCTCACAGCAG GGCCTGGCGACCTCACCCCGGACCTGCATCATCCGGACTCCATACCTCCAGCTCACCGAGGGCCTGGAGA CCTCACCCCTGACCTGCACCATCCGGACACCGCATATCCAGCTCACAGCAGGGTCTGGCGACCTCACCCC GGACCGGCACCATCCGGACTCCATACATCCAGCTCACCGAGGGCCTGGCGACCTCACTCCAGACCTGCAC CATCCAGACACCGCACATCCAGCTCACCGCAGGGTCTGGCGACCTCACCCCGGACCTGCACCATCTGGAC ACTGCACATCCAGCTCACCGAGGGCCTGGCGACCTCACTCCAGACCTGCACCATCCAGACACCACACATC CAGCTCACAGCAGGGCCTGGCGACCTCACCCCAGACCTGCACCATCCAGACACCACACATCCAGCTCACA GCAGGGCCTGGTGACCTCACACCGGACCTGCAGCATCCGGACACCCCACATCCAACTCACAGCAGGGCCT GGCAACCTCACCCCAGACCTGCACCATCCGGACACCGCATATCCAGCTCACCGCACGGTCTGGCACCGTC TGGCGACCTCACTCCAGACCTGCACCATCCAGACACCGCACACCCAGCTCACCGCAGGGCCTGGTGACCT CACCCCAGACCTGCACCATCCAGACACCACACATCCAGCTCACAGCAGGGCCTGGCGACCTCACCCCGGA CCTGCATCATCCGGACTCCATACCTCCAGCTCACCGAGGGCCTGGAGACCTCACCCCTGACCTGCACCAT CCAGACACCACACATCCAGCTCACAGCAGGGCCTGGCGACCTCACCCCGGACCTGCATCATCCGGACTCC ATACCTCCAGCTCACCGAGGGCCTGGAGACCTCACCCCTGACCTGCACCATCCAGACACCACACATCCAG CTCACAGCAGGGCCTGGCGACCTCATCCCAGACGTGCACCATCCGGACACTGCACATCCAGCTCACTGAG GGCCTGGCGACCTCATCCCGGACCTGCACCATCTGGTACAACAGCCATGGCCATGGGAAGCCCAGCAGGT CCAGGCCGAGATGGCCACGCACGGGACCTACACACGGGATCCCGCAGACAAAGCTCAAAAAATGTCAAAT GTCCTGTGAGTGATGCTCCCACCAATAACACCCTAAAATGATGAGGTGTGGACATGCTGGGCTTCAGTAA AATCTATTATTACATTAATTTCACCTTTTCTTTTTTACTTTTTTAATGTGGCTACTAGAATTTTTTTTTT TTTTTTTTTTTTTGAGACAGAGTCTCGCTGTGTTGCCAGGCTGGAGTGCAGTGGTGCAATGTCGGCTCAC TGCAACTTCCAACTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCA CCCGCCACCACGCCCAGCTAATTTTTGTGTTTTTAGTACAGATGGGGTTTCATCATGTTGGCCAGGATGG TCTCGACCTCCTGACCTCGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCA CCGCGCCCAGCCTAGAAATTTTAAAATTATCCACATGGCTCACGTCATGCTCCTGTTGGGCGACAACGGC TCGGAGCCTCATCCTTTGTCCTGGTTCCCAAGCAGAAGGGAGGAAGCAGACACTCCCCCGCCAGGCAGCA CCGTCAGAGCTGGCGCCACACCGCAGGTTTGCGCGATTTCAAACTCGACACCGCGGAGCCACCAGACCCC GACATGCCTGGGGTTTTCCAGGCTGAACCCAGGCCGAGCGGACGTTGCTGTCACTCACTGGCTAAGGAAC GCTGGCCACGTGGTGCTCCAGACACTCACGGGCCAAGATGACCGCCCTCCTCGTGAGTCTCCACATCTTC ATCTGTGCATCATAAGCAGAGGTCCCCGGACGTCGCTAGATGCCATGGAGGCCAGCACAGGTAAAGCTGG GGTTTACCAGCAATAACAAGACAGAAGAACCACGCAAAGGACAAGGAAGGGGACCCCAGACGGCGGGCCT GAGACAGAAGACAGACGGGGAACAAAGGAGGAAAAGCAGGGCGGGGGCAAAGCTACAGAAACACTCAACA CGGAAAACAATATTAATAATGCTTAGCTTGTGGGGGTGTCAAGATGCCTGAGATAGAACTAAGTCAGCAG GGAAAACAGCACACAGGCTGGGGGGTGGCCAGAGCTAAAATACACTAAGGGTCTTATTGCTCAGGACAAG GGTAGCAATGTTTCAGACTTCATTTTAAAAGATCAAGGTATGCCGGGCACGGTGGCTTGCACCTGTAATC CCAGCACTGTGGGAGGCCAAGGCGGGCAGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACAT GGTGAAAGCCTATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAATCCCAGC TACTCATGAGGTTGAGGAATGAGAACTGCTTGAACCGAGGAGGCAGAGGTTGCAGTGAGCCGAGATTGTG CCATTACACTCCAGCCTGGGTGACAGAGTGAGACTGTCTCAATAAACAAAAGCAAACAACGACAATAAAA AGATCAGGGGGTAACACTAAGCAAAGAGAAATAAAAGCAAATGCCCAGTGACCAGGAGGCAACGAGAGGA TCAACACACACTCGGCAGGAAACGCACATGGCAACCCAAGAGGTGGTGAGAAACAAGGGAACGAGGACAT GCAACAGGCAAGTGGAGAATCAGAGTGCACCAGGCGGGTCTCTAGTGACAAAAAAATGAAAATAAATCAG GTTATCCAGTTAAACAACGACTGTCAGACTGGATTGGAAATTCACCTACATGCTGTTAACAGGACATACC CACACTATAAGAATATAAAAGTGTTGAAAATTAGGCCAGACATGGTGGCTCATGCCTGTAATTCAGCACT TTGGGAAGCCGAGGTAGATGGATCCCTTGAGTCCAAGAGTTTGAGACCAGCCTGGGCAACACAGCAAGAC CCTGTCTCCAGAAAAAATTTAAAAATTAGCCAGGTGTAGCGGTGCGTGTCTGCAGTTCCAGCTATTCAGG AGGCTGAGGTGAGAGGACGGCTCAGGCCAGAAGGTAAAAGTTACACTGACCTGTGATCACACCACTGCAC TCACCCTGGGCGACAGACCAAGACTCTGTCTCAAAAAAAAAAAATATATATATATATATATAAATTAAAG GCAGAAAACAGACACAGCAGGAAAATACTAATCAAAAGAAGCCCAGTGTGGCAGTACTAAGAGCAATTTA AAAAAAGAATTACTAGATTACTAGAGACATAGAAGTCTCCAAAAGATTCACTCATCAGGAAGATAAAAAT TCTACCACGTGCATGCACCTAACAATGCCTCACATAAATGCTACCAAACGAGAAGAAATGAACAGACCCA TCCCCCAGGTGAGGGACTATGGCCTCCTTCTTGGAATTTCATGCATCTAGAAGGAGACAGAAGCTTTGCA CTGGACCTTAATAAGCTGGATATAGTGAACATGCATGCCCACTATTGACAGGATGTCAAATTTACAATGG ACAGTTCTGGAAACCATGCACACACTAGATCACAAAGCAAGGCTCCGCAAACTTCAAATAATTGGTATTA TACAGACCACTACACAACTGAGTTAGAAATCAATAATAAAATGATAACTTAAAATACTCTACGTATCTTG ATACTCTACATATCTTGAACATAAACAGTGTTCAAATAACTCACTGCTCAAAGAAATCACAGAATAAGCT AAAGAATACTTAAAAGTCACTGATATCAAAATGATTTCACGTCAAAACACAGCGTGCACAAAGAAAAAAA TCACAGAATAAGAATACTTAAAAGAAGTATTAACACTTTGAAGTATTTTAAGAACACTTGAAAGTGGCTG ATGTTGAGATTACTTCACATCAAAACACAGGGTGCAGGTAAGGCAGCACTTAGAGGGAAAGGCATGACTA AACTAAGAAGCTAGAAAAGGAATGAAAGAATAAACCAAGAAAAAGCATACAATGGAGAGATAGAAACGTC AGAGGTAAATCAGTGAAATTCAAAACTAAGACCCAAGAGGGAAGTCTGACGAAGGCTGGCGGAGACACCG GCCCTCCACGTGGGTCTCAGAGCAGGAGACAGACAGAGACACTCCAACCTGTGGCTGGACGTCAATCCAT GTGAGGGGGCGACTGGAGGCAGAGCCCAGCCTAAGCAATGAGCGGCAGGTGCCCAGAATAAGGTGACAAG CGTTGCCACCCACCCAAGGGGGCCAAGCAGAGGGGCAGCTTGGGAGAAAACAGGACAAGTGAGGGGGCTG GGGTGACTTGCTTTCCTTCAGGGCACAGAGAACCCTTTCTGGGATGTCTCCAGCAACACGTGGCAGCAGA CACAGGCAGCCCAGAGTCCAGCCTCGGCATGAGACAAGCTGGGAGAGGAGTATTGGCAGCATGCATGTGG CGGGCACGTGGTGAGCAAGCCAGGCCCAACAGAGGCAAGCGGACCTGAAGCTGTGGCTGCAGTGCCTGGC ACGCGGGAGGCGAGAGCCTGCAGTCCCGTGTCCCCGTAGCAAAATGGAACGGAGAGGTGACCAAGAAGAG CCGAGCATCAGAAAAGATAGGCTTGGGGACCAGCACTGCGCCTGCACCATCTACCCAGGCAATGGGCAAC CGGCGCAGCTGTGGCTATAGAAAGAGCAAACATTCAGGAGCAAGCTCAAGTGAGCAAACGCCAAGGACAC CTGGGGACAGAGCCTCACTCACCCTACACGAGACAGGGACACCCAGGGACAGCGCCTCACTCACCCTGCA CCTGAGAGGGACACCCGGGGGCCGCAACTCACTCACCCTACACGTGACAGGGACACCCGGGGACGGCGCC TCACTCACCCTACACGTGACAGGGACACCCGGGGATGGCGCCTCACTCACCCTACACCTGAGAGGGACAC CCAGGGACGGCGCCTCACTCACCCTACACGTGACAGAGACACCCGGGGACAGTGCCTCACTCACCCTACA CGTGACAGGGACACCCGGGGACGGGGCCTCACTCACCCTGCACGTGACAGGGACACCCGGGGACGGCGCC TCACTCACCCTACACGTGACAGGGACACCCGGGGACGGCGCCTCACTCACCCTACACGTGACAGGGACAC CCGGGGACGGCGCCTCACTCACCCTACACGTGACAGGGACACCCGGGGACGGCGCCTCACTCACCCTACA CGTGACAGGGACACCCGGGGACGGCGCCTCACTCACCCTGCACGTGACAGGGACACGCGGGGACGGCGCC TCACTCACCCTGCACGTGACAGGGACACCCGGGGGCCTCGCGTCAATCACCCTGCACGTGACAGGGACAC CCGGGGACGGCGCCTCACTCACCCTGCACGTGACAGGGACACCCGGGGACAGTGCCTCATTCACCCTACA CGTGACAGGGACACCCGGGGACCGCGCCTCACTCACCCTGAACGTGACAGGGACACCCGGGGACAGTGCC TCACTCACCCTGCAAGTGACAGGGACACCCGGGGGCCGCGCCTCACTCACCCTGCACGTGACAGGGACAC CCGGGGGCCGTGCCTCACTCACCCTGCACGTGACAGGGACACCCGGGGGCCGCGCCTCACTCACCCTGCA CGTGACAGGGACACCCGGGGGCCGCGCCTCACTCACCCTGCACGTGACAGGGACACCCGGGGGCCGCGCC TCACTCACCCTACACGTGACAGGGACACCCGGGGGCCGCGCCTCACTCACCCTGCACGTGACAGGGACAC CCGGGGGCCGCGCCTCACTCACCCTACACGTGACAGGGACACCCGGGGACAGTGCCTCACTCACCCTACA CGTGACAGTGACACCCGGGGACCGCGCCTCACTCACCCTACACGTGACAGGGACACCCGGGGGCCGTGCC TCACTCACCCTGAACGTGACAGGGACACCCGGGGACGGCGCCTCACTCACCCTACACGTGACAGGGACAC CCGGGGACGGCACCTCACTCACCCTACACGTGACAGGGACACCCGGGGACGGCGCCTCACTCACCCTGCA CGTGACAGGGACACGCGGGGACGGCGCCTCACTCACCCTGCACGTGACAGGGACACCCGGGGGCCTCGCG TCAATCACCCTGCACGTGACAGGGACACCCGGGGACAGCGCCTCACTCACCCTGCACGTGACAGGGACAC CCGGGGACGGTGCCTCACTCACCCTACACGTGACAGGGACACCCGGGGACCGCGCCTCACTCACCCTGAA CGTGACAGGGACACCCGGGGACAGTGCCTCACTCACCCTACACGGGACAGGGACACCCGGGGACCGTGCC TCACTCACCCTGCACGTGACAGGGACACCCGGGGACCGCGCCTCACTCACCCTGCACGTGACAGGGACAC CCGGGGACCGCGCCTCACTCACCCTGCACGTGACAGGGACACCCGGGGACCGCGCCTCACTCACCCTGCA CGTGACAGGGACACCCGGGGGCCGCGCCTCACTCACCCTGCACGTGACAGGGACACCCGGGGGCCGCGCC TCACTCACCCTGCACGTGACAGGGACACCCGGGGGCCGTGCCTCACTCACCCTGCACGTGACAGGGACAC CCGGGGACGGCGCCTCACTCACCCTGCACGGGACAGGGACACCTGGGGACCGCGCCTCACTCACCCTGCA CGGGACAGGGACACCCGGGGACAGTGCCTCACTCACCCTACACGTGACAGGGACACCTGGGGACCGCGCC TCACTCACCCTGCACGTGACAGGGACACCCGGGGACAGTGCCTCACTCACCCTATACCTGGGAGGGACAC CCAGGGACGGTGCCTCACTCACCCTACACGTGACAGGGACACCTGGGGCCGCGCCTCACTCACCCTACAC CTGAGAGGGACACCCGGGGACAGCGCCTCACTCACCCTACACCTGGGAGGGACACCCAGGGACGGTGCCT CACTCACCCTACACGTGACAGGGACACCCGGGGACCGCGCCTCACTCACCCTGCACGTGACAGGGACACC CGGGGACAGCGCCTCACTCACCCTGCACGGGACAGGGACACCCGGGGACCACGCCTCACTCACCCTACAC GTGACAGGGACACCCGGGGACGGCGCCTCACTCACCCTACACCTGAGAGGGACACCCGGGGACAGTGCCT CACTCACCCTACACGTGACAGGGACACCCGGGGACCGCGCCTCACTCACCCTGCACGTGACAGGGACACC CGGGGACAGTGCCTCACTCACCCTGCACGGGACAGGGACACCCGGGGGCCACACCTCAATCACGCTGCAC GGGACAGGGACACCCGGGGGCCGCGCCTCACTCACCCTACACGTGACAGGGACACCTGGGGGCAACGCCT CACTCACCCTGCACGTGACAGGGACACCCGGGGACCACGCCTCACTCCCTGCATAAGCCAGGGGCAGATT GTGACCTCATCTGAAGTCAGAGAACAGCAATGACAGGCAGAGTCCTGATCAGAGAACTCAAACTCTCCTC AACGAAGGAAGCTGGAGCACAAAAAGCAAAACTGGGTTGCATGACGCTTATCTGACTCGGCGTGGTCCAC CTGAGCCGCAGCAGGTGTGAGGCAGCTGCCGTTCGATGGGTAGGGACTTCCAGTCACGCAAGACGCAGCA TTTCAAGCAACCTGCTGTAAACACCGCCGAGTTAGCAATTCTGCACTGTACACAGAAAACGGTGTTAGGA GTGCCAATCTCATGTTATATGACTTTTGCCACCATAAAAAGAAAAAAAGAAAAAAAAGAGCCCCAAGAAG GTCACCCTCCTTGTCTGCATGGCCGGAAGTCTTACATGTCTTGGGAGTTTGTGGGGAGGGGGTGAAATCG GGACTTCTTCTAGCTGCCACGGTAGGGCCTGGGAGCACTGGGAGCCAAAAGGGGGCTGGAGCGGAGGTTC CTCAACATCAAATCCAGAAAAACAGGGTGGGGACACGGCAGGGCCCAGCAGCACCATCCCCTGAACACCC ACAAACACTGTCCCTTCCTCAGCAGGTGGAGCCATCTGCTGTCCTCTGCTCCCATGTGGCCCTCTTCATA CCTAAAGATGGGACCAGGATCTGTGCTGGAGAACAGTCTTATCTCCCTCCCTCTACCCTGTCCTGGCACA ATCAACGAACACTTTTTTTTTTTAAAGACAGAGTTTCACTCTTGTCGCCCAGGCTGGAGTACAATGGCAC AATCTCAGCTCACTGCAGCCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCT GGGATTACAGGCACACACCACCATGCCCAGCTAATTTTTGTATTTTTAGTACAGATAGGGTTTCACCATG TTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTCAGCTTCCCAAAGTGCTGGGAT TACCGGCGTGAGCCACCGCACCTGGCCGTCAACACACAATTAAATCTTAAACACAAACCTGCATATTGGC TGACCACGTGCACCTGCAAAACCCTTACCTCCCACCCCCAGGAAGAGGGGGTTCTCGTCCCCACCTCTCA TTCCCACCCTTGAAATTGCGAAGAGGATTATAGGTAACCTGCAGGCACCCTCGCCAGAGCGTCTGTGCTT CCAGACACTTCTCCCCATTGCCGGCAACCCGGCTCCACTGCCGCGCCCAGCCTCCTCTGTTCACTGCTCT GGCCTCGGCGCCTGGAAACCGCGTGTCCATCAAAACGTGAAGGTGAACCTCGTAAGTTTATGCAAACTGG ACAGGAGGGAGAGCAGAGGCAGAGATCACCGTGTCCACTCGACGTCCTGAGCGAAAAGCCACGTGTGCCC ACGTGACGATGGAGACAGGAGGACCAGGGCTCTGCCTGCCCCCTTTTCTGAGCCCCTACTGCATTCAGCT CTGGGGCCTGGGCCCTCGACGGCCACCACCTCCTCACCTGGGCTCCTGCGCAGCCAAGCGCAGTCCCGCA CGCTCATCTTCCACGTCAGCTCCTGCAGCGAGAGCTTGGCATGCTTCCCCAGGGAGATGAACTTCTTGGT GTTCCTGAGGAAGCGGCGTTCGTTGTGCCTGGAGCCCCAGAGGCCTGGGGGCACCAGCCGGCGCAGGCAG GCCCGCACGAAGCCGTACACCTGCCAGGGGCTGCTGTGCTGGCGGAGCAGCTGCACCAGGCGACGGGGGT CTGTGTCCTCCTCCTCGGGGGCCGCCACAGAGCCCTGGGGCTTCTCCCGGGCACAGACACCGGCTGCTGG GGTGACCGCAGCTCGCAGCGGGCAGTGCGTCTTGAGGAGCACCCCGTAGGGGCACTGCGCGTGGTTCCCA AGCAGCTCCAGAAACAGGGGCCGCATTTGCCAGTAGCGCTGGGGCAGGCGGGGCAACCTGCGGGGAGTCC CTGGCATCCAGGGCCTGGAACCCAGAAAGATGGTCTCCACGAGCCTCCGAGCGCCAGTCAGGCTGGGCCT CAGAGAGCTGAGTAGGAAGGAGGGCCGCAGCTGCTCCTTGTCGCCTGAGGAGTAGAGGAAGTGCTTGGTC TCGGCGTACACCGGGGGACAAGGCGTGTCCCAGGGACGTGGTGGCCGCGATGTGGATGGGGGGCCCGCGT GGTGCTGGCGGCCCACGGATGGGTGGGAGTGGCGCGTGCCAGAGAGCGCACCCTCCAAAGAGGTGGCTTC TTCGGCGGGTCTGGCAGGTGACACCACACAGAAACCACGGTCACTCGGTCCACGCGTCCTGCCCGGGTGG GCCCAGGACCCCTGCCCAACGGGCGTCCGCTCCGGCTCAGGGGCAGCGCCACGCCTGGGCCTCTTGGGCA ACGGCAGACTTCGGCTGGCACTGCCCCCGCGCCTCCTCGCACCCGGGGCTGGCAGGCCCAGGGGGACCCC GGCCTCCCTGACGCTATGGTTCCAGGCCCGTTCGCATCCCAGACGCCTTCGGGGTCCACTAGCGTGTGGC GGGGGCCGGGCCTGAGTGGCAGCGCCGAGCTGGTACAGCGGCGGCCCGCACACCTGGTAGGCGCAGCTGG GAGCCACCAGCACAAAGAGCGCGCAGCGTGCCAGCAGGTGAACCAGCACGTCGTCGCCCACGCGGCGCAG CAGCAGCCCCCACGCCCCGCTCCCCCGCAGTGCGTCGGTCACCGTGTTGGGCAGGTAGCTGCGCACGCTG GTGGTGAAGGCCTCGGGGGGGCCCCCGCGGGCCCCGTCCAGCAGCGCGAAGCCGAAGGCCAGCACGTTCT TCGCGCCGCGCTCGCACAGCCTCTGCAGCACTCGGGCCACCAGCTCCTTCAGGCAGGACACCTGCGGGGG AAGCGCCCTGAGTCGCCTGCGCTGCTCTCCGCATGTCGCTGGTTCCCCCCGGCCGCCCTCAACCCCAGCC GGACGCCGACCCCGGGGAGGCCCACCTGGCGGAAGGAGGGGGCGGCGGGGGGCGGCCGTGCGTCCCAGGG CACGCACACCAGGCACTGGGCCACCAGCGCGCGGAAAGCCGCCGGGTCCCCGCGCTGCACCAGCCGCCAG CCCTGGGGCCCCAGGCGCCGCACGAACGTGGCCAGCGGCAGCACCTCGCGGTAGTGGCTGCGCAGCAGGG AGCGCACGGCTCGGCAGCGGGGAGCGCGCGGCATCGCGGGGGTGGCCGGGGCCAGGGCTTCCCACGTGCG CAGCAGGACGCAGCGCTGCCT
Protein Sequence	>NP_001180305.1 telomerase reverse transcriptase isoform 2 [Homo sapiens] MPRAPRCRAVRSLLRSHYREVLPLATFVRRLGPQGWRLVQRGDPAAFRALVAQCLVCVPWDARPPPAAPS FRQVSCLKELVARVLQRLCERGAKNVLAFGFALLDGARGGPPEAFTTSVRSYLPNTVTDALRGSGAWGLL LRRVGDDVLVHLLARCALFVLVAPSCAYQVCGPPLYQLGAATQARPPPHASGPRRRLGCERAWNHSVREA GVPLGLPAPGARRRGGSASRSLPLPKRPRRGAAPEPERTPVGQGSWAHPGRTRGPSDRGFCVVSPARPAE EATSLEGALSGTRHSHPSVGRQHHAGPPSTSRPPRPWDTPCPPVYAETKHFLYSSGDKEQLRPSFLLSSL RPSLTGARRLVETIFLGSRPWMPGTPRRLPRLPQRYWQMRPLFLELLGNHAQCPYGVLLKTHCPLRAAVT PAAGVCAREKPQGSVAAPEEEDTDPRRLVQLLRQHSSPWQVYGFVRACLRRLVPPGLWGSRHNERRFLRN TKKFISLGKHAKLSLQELTWKMSVRDCAWLRRSPGVGCVPAAEHRLREEILAKFLHWLMSVYVVELLRSF FYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGL RPIVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQ DPPPELYFVKVDVTGAYDTIPQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQ PYMRQFVAHLQETSPLRDAVVIEQSSSLNEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTL LCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLSYARTSIRASLTFNRGFKAGRNMRRK LFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLC YSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLLKLTRHRVTYVPLLGSLRTAQTQLSRKLPGTTLT ALEAAANPALPSDFKTILD
Molecule Role	Protective antigen
Molecule Role Annotation	Telomerase is expressed in 85-90% of pancreas cancer, and immunogenic telomerase peptides have been characterised. A phase I/II study was conducted to investigate the safety, tolerability, and immunogenecity of telomerase peptide vaccination. Forty-eight patients with non-resectable pancreatic cancer received intradermal injections of the telomerase peptide GV1001 at three dose levels, in combination with granulocyte-macrophage colony-stimulating factor. Monthly booster vaccinations were offered as follow-up treatment. Immune responses were measured as delayed-type hypersensitivity skin reaction and in vitro T-cell proliferation. GV1001 was well tolerated. Immune responses were observed in 24 of 38 evaluable patients, with the highest ratio (75%) in the intermediate dose group. Twenty-seven evaluable patients completed the study. Median survival for the intermediate dose-group was 8.6 months, significantly longer for the low- (P = 0.006) and high-dose groups (P = 0.05). One-year survival for the evaluable patients in the intermediate dose group was 25% (Bernhardt et al., 2006).
Related Vaccines(s)	Autologous Renal Cell Carcinoma Tumor Lysate-Pulsed Dendritic Cell Vaccine , Cancer Subunit GV1001 Protein Vaccine , hTERT I540/R572Y/D988Y Multipeptide Vaccine , hTERT mRNA/Survivin Peptide-double-loaded Autologous Dendritic Cell Vaccine , hTERT Multipeptide/Montanide ISA-51 VG/Imiquimod Vaccine GX 301 , hTERT Vaccine V934/V935 , hTERT-LAMP mRNA-loaded Autologous Dendritic Cell Vaccine GRNVAC1 , hTERT/Survivin/Melanoma Tumor Cell-Derived mRNA-Transfected Dendritic Cell Vaccine , Ovarian Cancer Stem Cell/hTERT/Survivin mRNAs-loaded Autologous Dendritic Cell Vaccine , Primary Prostate Cancer Tissue/hTERT/Survivin mRNA-loaded Autologous Dendritic Cell Vaccine , Recombinant Vaccinia-CEA(6D)-TRICOM Vaccine , Survivin Sur1M2 Peptide Vaccine , Synthetic hTERT DNA Vaccine INO-1400 , Telomerase-specific Type 5 Adenovirus OBP-301 Vaccine , Telomerase: 540-548 Peptide Vaccine , UV1 Telomerase Peptide Vaccine
References

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