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VP2

Gene Name VP2
Sequence Strain (Species/Organism) Rotavirus sp.
VO ID VO_0011254
NCBI Protein GI 431460
Other Database IDs CDD:282884
Taxonomy ID 10970
Gene Strand (Orientation) ?
Protein pI 5.78
Protein Weight 97494.97
Protein Length 928
Protein Note Rotavirus VP2 protein; pfam05087
Protein Sequence
>AAA47305.1 VP2 [Rotavirus sp.]
MAYRKRGARRETNLKQDERMQEKEDSKNINNDSPKSQLSEKVLSKKEEIITDNQEEVKISDEVKKSNKEE
SKQLLEVLKTKEEHQKEVQYEILQKTIPTFEPKESILKKLEDIKPEQAKKQTKLFRIFEPKQLPIYRANG
ERELRNRWYWKLKRDTLPDGDYDVREYFLNLYDQVLMEMPDYLLLKDMAVENKNSRDAGKVVDSETAAIC
DAIFQDEETEGAVRRFIAEMRQRVQADRNVVNYPSILHPIDHAFNEYFLQHQLVEPLNNDIIFNYIPERI
RNDVNYILNMDRNLPSTARYIRPNLLQDRLNLHDNFESLWDTITTSNYILARSVVPDLKELVSTEAQIQK
MSQDLQLEALTIQSETQFLTGINSQAANDCFKTLIADMLSQRTMSLDFVTTNYMSLISGMWLLTVIPNDM
FIRESLVACQLAIINTIVYPAFGMQRMHYRNGDPQTPFQIAEQQIQNFQVANWLHFVNYNQFRQVVIDGV
LNQVLNDNIRNGHVVNQLMEALMQLSRQQFPTMPVDYKRSIQRGILLLSNRLGQLVDLTRLLSYNYETLM
ACITMNMQHVQTLTTEKLQLTSVTSLCMLIGNATVIPSPQTLFHYYNVNVNFHSNYNERINDAVAIITAA
NRLNLYQKKMKSIVEDFLKRLQIFDVARVPDDQMYRLRDRLRLLPVEIRRLDIFNLIAMNMEQIERASDK
IAQGVIIAYRDMQLERDEMYGYVNIARNLDGFQQINLEELMRSGDYAQITNMLLNNQPVALVGALPFITD
SSVISLIAKLDATVFAQIVKLRKVDTLKPILYKINSDSNDFYLVANYDWIPTSTTKVYKQVPQQFDFRAS
MHMLTSNLTFTVYSDLLAFVSADTVEPINAVAFDNMRIMNEL

Molecule Role Protective antigen
Molecule Role Annotation Both inbred BALB/c and outbred CD-1 mice were immunized with rotavirus VP2/6-rVLPs (2/6-VLPs) combined with CT-E29H, orally or intranasally (i.n.), and the comparative efficacy of different formulations was then determined. Two immunizations with 2-6VLPs and CT-E29H were sufficient to protect BALB/c mice, regardless of the route of administration (Siadat-Pajouh and Cai, 2001).
Related Vaccines(s) HSVT[VP7/6/2] , Rotavirus VP2/VP 6 Protein Vaccine
References