VIOLIN: Vaccine Investigation and Online Information Network

MSP4/5
Gene Name	MSP4/5
Sequence Strain (Species/Organism)	Plasmodium yoelii
VO ID	VO_0011236
NCBI Gene ID	3800676
NCBI Nucleotide GI	AY563017.1
NCBI Protein GI	49798469
Other Database IDs	CDD:289699
Taxonomy ID	73239
Gene Strand (Orientation)	?
Protein Name	merozoite surface protein 4/5
Protein pI	4.1
Protein Weight	18420.75
Protein Length	253
Protein Note	EGF domain; pfam12947
Protein Sequence	>AAT68597.1 merozoite surface protein 4/5, partial [Plasmodium yoelii yoelii] VHEISLINTKKYQRNIFCAKRILGDPPSANPSTSLNQNEDNHNSNPDANKGNTNKSDKLNGDNIPNSQSK SENTNLSESPKTGTASNPPQPEPSVQPGNTNGDSQNSIHSDDEEEDDEDEDDDEEDCSVNNGGCGENLLC EKMESGIIKCSCPSGYKLNGTSCIELLSAHS
Molecule Role	Protective antigen
Molecule Role Annotation	Oral immunization of mice with Escherichia coli-expressed Plasmodium yoelii merozoite surface protein 4/5 or the C-terminal 19-kDa fragment of merozoite surface protein 1 induced systemic antibody responses and protected mice against lethal malaria infection (Wang et al., 2004).
Related Vaccines(s)	P. yoelii MSP1 and MSP4/5 Proteins Subunit Vaccine
References