VIOLIN: Vaccine Investigation and Online Information Network

HEP17
Gene Name	HEP17
Sequence Strain (Species/Organism)	Plasmodium yoelii
VO ID	VO_0011228
NCBI Gene ID	3790041
NCBI Protein GI	1399353
Other Database IDs	CDD:284100
Taxonomy ID	5861
Gene Strand (Orientation)	?
Protein Name	hepatocyte erythrocyte protein 17 kDa
Protein pI	10.09
Protein Weight	17587.89
Protein Length	243
Protein Note	Circumsporozoite-related antigen (CRA); pfam06589
Protein Sequence	>AAC47199.1 hepatocyte erythrocyte protein 17 kDa [Plasmodium yoelii] MKINIASIIFIIFSLCLVNDAYGKNKYGKNGKYGSQNVIKKHGEPVINVQDLISDMVRKEEEIVKLTKNK KSLRKINVALATALSVVSAILLGGAGLVMYNTEKGRRPFQIGKSKKGGSAMARDSSFPMNEESPLGFSPE EMEAVASKFRESMLKDGVPAPSNTPNVQN
Molecule Role	Protective antigen
Molecule Role Annotation	Immunization of mice with subunit vaccines based on the Plasmodium yoelii 17kDa hepatocyte erythrocyte protein (PyHEP17), orthologue of Plasmodium falciparum exported protein 1 (PfExp1), induces antigen-specific immune responses and protects against sporozoite challenge (Dobaño and Doolan, 2007).
Related Vaccines(s)	P. yoelii DNA vaccine encoding PyHEP17 Protein
References