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ClpP
Gene Name	ClpP
Sequence Strain (Species/Organism)	Streptococcus pneumoniae D39
VO ID	VO_0011193
NCBI Gene ID	4441476
NCBI Protein GI	WP_000613477
Locus Tag	SPD_0650
Genbank Accession	CP000410
Protein Accession	YP_816144
3D structure: PDB ID	1Y7O
Other Database IDs	CDD:178955 CDD:132928
Taxonomy ID	1301
Gene Starting Position	668966
Gene Ending Position	669556
Gene Strand (Orientation)	+
Protein Name	ATP-dependent Clp protease proteolytic subunit
Protein pI	4.37
Protein Weight	22213.63
Protein Length	293
Protein Note	ATP-dependent Clp protease proteolytic subunit; Reviewed; PRK00277
DNA Sequence	>NC_008533.1:668966-669556 Streptococcus pneumoniae D39, complete genome AATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTC AAAGACCGCATCATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAACTGC TTTTCTTGGATGCCCAAGATAGTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTC AGCTGGTTTGGCAATCGTAGATACCATGAACTTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATG GCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAAAGGCAAACGTTTCATGCTTCCAAATGCTG AATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAACTGATATGGCTATCGCTGC AGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAGTCAATGGAA AAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTG ATGAAATTATGGCCAACAATTCATTGAACTA
Protein Sequence	>WP_000613477.1 MULTISPECIES: ATP-dependent Clp protease proteolytic subunit [Streptococcus] MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVS AGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAA EHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Molecule Role	Protective antigen
Molecule Role Annotation	The protective effects of ATP-dependent caseinolytic protease (ClpP) was evaluated. Vaccinated mice were intraperitoneally and/or intranasally challenged with different pneumococcal strains. In intraperitoneal challenge models with pneumococcal strain D39 (serotype 2), clpP elicited some protection in mice (Wu et al., 2010).
Related Vaccines(s)	S. pneumoniae ClpP protein Vaccine
References

ClpP