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HN

Gene Name HN
Sequence Strain (Species/Organism) Mumps rubulavirus
VO ID VO_0011171
NCBI Gene ID 1489765
NCBI Protein GI 9695422
Locus Tag MuVgp6
Genbank Accession AB040874
Protein Accession NP_054713
Taxonomy ID 1979165
Gene Starting Position 6613
Gene Ending Position 8361
Gene Strand (Orientation) ?
Protein Name hemagglutinin-neuraminidase
Protein pI 7.68
Protein Weight 59974.82
Protein Length 582
DNA Sequence 
>NC_002200.1:6613-8361 Mumps virus, complete genome
GATGGAGCCCTCCAAACTCTTCACAATGTCAGACAATGCCACCTTTGCACCTGGGCCTGTTATCAATGCG
GCTGACAAGAAGACATTCCGAACCTGCTTCCGAATATTGGTACTGTCTGTACAAGCTGTTACCCTTATAT
TAGTTATTGTCACTTTAGGTGAGCTTGTGAGGATGATCAATGATCAAGGCTTGAGCAATCAGTTGTCTTC
AATTGCAGACAAGATAAGAGAGTCAGCTACTATGATTGCATCTGCTGTGGGAGTAATGAATCAAGTTATT
CACGGAGTAACGGTATCCTTACCCCTACAAATTGAGGGAAACCAAAATCAATTGTTATCCACGCTTGCCA
CAATCTGTACAGGCAAAAAACAAGTCTCAAACTGCTCTACAAACATCCCCTTAGTTAATGACCTTAGGTT
TATAAATGGGATCAATAAATTCATCATTGAAGATTATGCAACTCATGATTTCTCTATCGGCCATCCACTC
AACATGCCTAGCTTTATCCCAACTGCAACTTCACCCAATGGTTGCACAAGAATTCCATCCTTTTCTCTAG
GTAAGACACACTGGTGCTACACACATAATGTAATTAATGCCAACTGCAAGGATCATACTTCGTCCAACCA
ATATATTTCCATGGGGATACTTGTTCAGACCGCGTCAGGGTATCCTATGTTCAAAACCTTAAAGATCCAA
TATCTCAGTGATGGCCTGAATCGGAAAAGCTGCTCAATTGCAACAGTCCCTGATGGATGCGCAATGTACT
GTTATGTCTCAACTCAACTTGAAACCGACGACTATGCGGGGTCCAGCCCACCTACCCAGAAACTTACCCT
GTTATTCTATAATGATACCGTCACAGAAAGGACAATATCTCCAACTGGTCTCGAAGGGAACTGGGCCACT
TTGGTTCCAGGAGTGGGGAGTGGAATATATTTCGAGAATAAATTGATCTTTCCTGCATATGGGGGTGTCT
TGCCCAATAGTTCACTCGGAGTTAAATCAGCAAGAGAATTTTTCCGGCCTGTTAATCCATATAATCCATG
TTCAGGACCACAACAAGATTTAGATCAGCGTGCTTTGAGATCATACTTCCCAAGTTACTTCTCTAATCGA
AGAGTACAGAGTGCATTTCTTGTCTGTGCCTGGAATCAGATCCTAGTTACAAATTGCGAGCTAGTTGTCC
CCTCAAACAATCAGACACTGATGGGTGCAGAAGGAAGAGTTTTATTGATCAATAATCGACTATTATATTA
TCAGAGAAGTACCAGCTGGTGGCCGTATGAACTCCTCTATGAGATATCATTCACATTTACAAACTCTGGT
CAATCATCTGTGAATATGTCCTGGATACCTATATATTCATTCACTCGTCCTGGTTCAGGCAACTGCAGTG
GTGAAAATGTGTGCCCAACTGCTTGTGTGTCAGGGGTTTATCTTGATCCCTGGCCATTAACTCCATATAG
CCACCAATCAGGCATTAACAGAAATTTCTATTTCACAGGTGCACTATTAAATTCAAGCACAACTAGAGTA
AATCCTACCCTTTATGTCTCTGCCCTTAATAATCTTAAAGTACTAGCCCCATATGGTAATCAGGGACTGT
TTGCCTCGTACACTACAACCACCTGCTTTCAAGATACCGGTGATGCTAGTGTGTATTGTGTTTATATTAT
GGAACTAGCATCGAATATCGTTGGAGAATTCCAAATTCTACCTGTGCTAACCAGATTGACCATCACTTG
Protein Sequence 
>NP_054713.1 hemagglutinin-neuraminidase [Mumps rubulavirus]
MEPSKLFTMSDNATFAPGPVINAADKKTFRTCFRILVLSVQAVTLILVIVTLGELVRMINDQGLSNQLSS
IADKIRESATMIASAVGVMNQVIHGVTVSLPLQIEGNQNQLLSTLATICTGKKQVSNCSTNIPLVNDLRF
INGINKFIIEDYATHDFSIGHPLNMPSFIPTATSPNGCTRIPSFSLGKTHWCYTHNVINANCKDHTSSNQ
YISMGILVQTASGYPMFKTLKIQYLSDGLNRKSCSIATVPDGCAMYCYVSTQLETDDYAGSSPPTQKLTL
LFYNDTVTERTISPTGLEGNWATLVPGVGSGIYFENKLIFPAYGGVLPNSSLGVKSAREFFRPVNPYNPC
SGPQQDLDQRALRSYFPSYFSNRRVQSAFLVCAWNQILVTNCELVVPSNNQTLMGAEGRVLLINNRLLYY
QRSTSWWPYELLYEISFTFTNSGQSSVNMSWIPIYSFTRPGSGNCSGENVCPTACVSGVYLDPWPLTPYS
HQSGINRNFYFTGALLNSSTTRVNPTLYVSALNNLKVLAPYGNQGLFASYTTTTCFQDTGDASVYCVYIM
ELASNIVGEFQILPVLTRLTIT
Molecule Role Protective antigen
Molecule Role Annotation A novel mumps vaccine with good immunity and safety was developed by selecting an antigen (HN) component of the mumps virus. The clinical and pathological observations after challenge of vaccinated rhesus monkeys indicated further that the immune response induced by this vaccine provided complete protection from wild-type virus infection (Liang et al., 2008).
Related Vaccines(s) Mumps HN Protein Subunit Vaccine , rvOka-HN (mumps virus)
References