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G glycoprotein

Gene Name G glycoprotein
Sequence Strain (Species/Organism) Infectious hematopoietic necrosis virus
VO ID VO_0011109
NCBI Gene ID 1489848
NCBI Protein GI 9628086
Locus Tag IHNVgp4
Genbank Accession KP216199
Protein Accession NP_042679
Taxonomy ID 11290
Gene Starting Position 2998
Gene Ending Position 4524
Gene Strand (Orientation) ?
Protein Name glycoprotein
Protein pI 6.5
Protein Weight 54073.98
Protein Length 508
DNA Sequence 
>NC_001652.1:2998-4524 Infectious hematopoietic necrosis virus, complete genome
AATGGACACCATGATCACCACTCCGCTCATTCTCATTCTGATCACCTGCGGAGCAAACAGCCAAACCGTC
AAACCCGACACCGCAAGCGAATCAGACCAACCCACCTGGTCAAACCCGCTCTTCACCTATCCCGAGGGAT
GCACTCTGGACAAGCTCTCTAAGGTCAATGCCTCTCAACTGAGATGCCCAAGGATCTTCGACGATGAGAA
CAGGGGGCTAATTGCCTATCCCACATCCATCCGGTCCCTGTCAGTCGGAAACGACCTCGGGGACATTCAC
ACCCAAGGGAACCACATCCACAAAGTCCTGTACCGCACAATCTGCTCAACAGGGTTCTTCGGGGGTCAGA
CGATAGAGAAGGCGCTTGTAAAAATGAAACTCTCTACGAAAGAAGCAGGGGCGTATGACACCACAACCGC
AGCCGCTCTGTACTTCCCAGCTCCCCGATGCCAATGGTACACCGACAACGTACAAAACGATCTCATCTTC
TACTACACAACACAAAAGAGTGTTCTTAGAGATCCCTACACCAGAGACTTTCTGGACTCAGATTTTATTG
GAGGAAAATGTACCAAATCACCCTGCCAGACTCATTGGTCCAACGTAGTTTGGATGGGTGATGCAGGGAT
ACCAGCCTGTGATTCCAGCCAAGAGATAAAAGCTCACCTCTTTGTTGATAAAATCTCCAATCGAGTCGTG
AAGGCAACGAGCTACGGACACCACCCCTGGGGACTGCATCAGGCCTGTATGATTGAATTCTGTGGGCAAC
AGTGGATACGGACAGATCTCGGTGACCTAATATCTGTCGTATACAATTCTGGATCAGAAATCCTCTCGTT
CCCGAAGTGTGAAGACAAGACCGTGGGAATGAGGGGAAACTTGGATGACTTTGCCTATCTAGACGATCTG
GTGAAGGCCTCTGAGAGCAGAGAGGAATGTCTTGAGGCGCACGCCGAGATAATATCAACAAACAGTGTGA
CTCCATACCTCCTATCCAAATTCCGATCTCCACATCCCGGAATAAATGACGTCTACGCTATGCACAAAGG
CTCCATCTATCACGGGATGTGCATGACGGTCGCTGTGGACGAGGTATCCAAGGACAGGACAACGTACAGG
GCCCATCGCGCTACCAGCTTCACGAAATGGGAACGACCCTTTGGGGATGAGTGGGAGGGCTTTCACGGAT
TGCACGGAAACAACACCACCATTATTCCAGACCTGGAGAAATACGTCGCCCAGTACAAGATGAGCATGAT
GGAACCGATGAGCATCAAATCCGTACCCCATCCAAGCATCCTGGCCCTCTACAATGAGACAGACGTGTCA
GGGATCTCCATCAGGAAACTGGACTCATTCGACCTTCAATCACTCCACTGGAGTTTCTGGCCCACAATCT
CCGCACTGGGTGGAATTCCCTTTGTTCTCCTCCTTGCTGTTGCCGCGTGCTGCTGCTGGTCAGGGAGACC
TCCCACTCCCTCCGTGCCGCAGAGTATCCCCATGTATCACCTGGCAAACCGGTCCTA
Protein Sequence 
>NP_042679.1 glycoprotein [Infectious hematopoietic necrosis virus]
MDTMITTPLILILITCGANSQTVKPDTASESDQPTWSNPLFTYPEGCTLDKLSKVNASQLRCPRIFDDEN
RGLIAYPTSIRSLSVGNDLGDIHTQGNHIHKVLYRTICSTGFFGGQTIEKALVKMKLSTKEAGAYDTTTA
AALYFPAPRCQWYTDNVQNDLIFYYTTQKSVLRDPYTRDFLDSDFIGGKCTKSPCQTHWSNVVWMGDAGI
PACDSSQEIKAHLFVDKISNRVVKATSYGHHPWGLHQACMIEFCGQQWIRTDLGDLISVVYNSGSEILSF
PKCEDKTVGMRGNLDDFAYLDDLVKASESREECLEAHAEIISTNSVTPYLLSKFRSPHPGINDVYAMHKG
SIYHGMCMTVAVDEVSKDRTTYRAHRATSFTKWERPFGDEWEGFHGLHGNNTTIIPDLEKYVAQYKMSMM
EPMSIKSVPHPSILALYNETDVSGISIRKLDSFDLQSLHWSFWPTISALGGIPFVLLLAVAACCCWSGRP
PTPSVPQSIPMYHLANRS
Molecule Role Protective antigen
Molecule Role Annotation The DNA vaccine pIHNw-G encodes the glycoprotein of the fish rhabdovirus infectious hematopoietic necrosis virus (IHNV). Vaccine performance in rainbow trout was measured 3, 6, 13, 24, and 25 months after vaccination. At three months all fish vaccinated with 0.1 microg pIHNw-G had detectable neutralizing antibody (NAb) and they were completely protected from lethal IHNV challenge with a relative percent survival (RPS) of 100% compared to control fish (Kurath et al., 2006).
Related Vaccines(s) IHNV DNA vaccine pCDNA-G encoding G , IHNV DNA vaccine pCMV4-G , IHNV DNA vaccine pIHN-G encoding glycoproteins , IHNV DNA vaccine pIHNw-G
References