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CDVgp5
Gene Name	CDVgp5
Sequence Strain (Species/Organism)	Canine morbillivirus
VO ID	VO_0011053
NCBI Gene ID	1489793
NCBI Protein GI	9630650
Locus Tag	CDVgp5
Genbank Accession	AF014953
Protein Accession	NP_047205
Taxonomy ID	11232
Gene Starting Position	4934
Gene Ending Position	6922
Gene Strand (Orientation)	+
Protein Name	fusion protein F
Protein pI	9.25
Protein Weight	69080.65
Protein Length	662
DNA Sequence	>NC_001921.1:4934-6922 Canine distemper virus, complete genome CATGCACAAGGGAATCCCCAAAAGCTCCAAAACCCAAACACATACCCAACAAGACCGCCCCCCACAACCC AGCACCGAACTCGAAGAGACCAGGACCTCCCGAGCACGACACAGCACAACATCAGCTCAGCGATCCACGC ACTACGATCCTCGAACATCGGACAGACCCGTCTCCTACACCATGAACAGGACCAGGTCCCGCAAGCAAAC CAGCCACAGATTGAAGAACATCCCAGTTCACGGAAACCACGAGGCCACCATCCAGCACATACCAGAGAGT GTCTCAAAAGGAGCGAGATCCCAGATCGAAAGGCGGCAACCCAATGCAATCAACTCAGGCTCTCAGTGCA CCTGGTTAGTCCTGTGGTGCCTCGGAATGGCCAGTCTCTTTCTTTGTTCCAAGGCTCAGATACATTGGAA TAATTTGTCAACTATTGGGATTATCGGGACTGATAGTGTCCATTACAAGATCATGACTAGGCCCAGTCAC CAGTACTTGGTCATAAAACTGATGCCTAATGTTTCACTTATAGAGAATTGTACCAAAGCAGAATTAGGTG AGTATGAGAAATTATTGAATTCAGTCCTCGAACCAATCAACCAAGCTTTGACTCTAATGACCAAGAATGT GAAGCCCCTGCAGTCATTAGGGTCAGGTAGGAGACAAAGGCGTTTTGCAGGAGTGGTACTTGCAGGTGTA GCTTTAGGAGTGGCTACAGCTGCACAAATCACTGCAGGAATAGCTTTACATCAATCCAACCTCAATGCTC AAGCAATCCAATCTCTTAGAACCAGCCTTGAACAGTCTAACAAAGCTATAGAAGAAATTAGGGAGGCTAC CCAAGAAACCGTCATTGCCGTTCAGGGAGTCCAGGACTACGTCAACAACGAACTCGTCCCTGCCATGCAA CATATGTCATGTGAATTAGTTGGGCAGAGATTAGGGTTAAGACTGCTTCGGTATTATACTGAGTTGTTGT CAATATTTGGCCCGAGTTTACGTGACCCTATTTCAGCCGAGATATCAATTCAGGCACTGATTTATGCTCT TGGAGGAGAAATTCATAAGATACTTGAGAAGTTGGGATATTCTGGAAGTGATATGATTGCAATCTTGGAG AGTCGGGGGATAAAAACAAAAATAACTCATGTTGATCTTCCCGGGAAATTCATCATCCTAAGTATCTCAT ACCCAACTTTATCAGAAGTCAAGGGGGTTATAGTCCACAGACTGGAAGCAGTTTCTTACAACATAGGATC ACAAGAGTGGTACACCACTGTCCCGAGGTATATTGCAACTAATGGTTACTTAATATCTAATTTTGATGAG TCATCTTGTGTATTCGTCTCAGAGTCAGCCATTTGTAGCCAGAACTCCCTGTATCCCATGAGCCCACTCT TACAACAATGTATTAGGGGCGACACTTCATCTTGTGCTCGGACCTTGGTATCTGGGACTATGGGCAACAA ATTTATTCTGTCAAAAGGTAATATCGTCGCAAATTGTGCTTCTATACTATGTAAGTGTTATAGCACAAGC ACAATTATTAATCAGAGTCCTGATAAGTTGCTGACATTCATTGCCTCCGATACCTGCCCACTGGTTGAAA TAGATGGTGCTACTATCCAAGTTGGAGGCAGGCAATACCCTGATATGGTATACGAAGGCAAAGTTGCCTT AGGCCCTGCTATATCACTTGATAGGTTAGATGTAGGTACAAACTTAGGGAACGCCCTTAAGAAACTGGAT GATGCTAAGGTACTGATAGACTCCTCTAACCAGATCCTTGAGACGGTTAGGCGCTCTTCCTTTAATTTTG GCAGTCTCCTCAGTGTTCCTATATTAAGTTGTACAGCCCTGGCTTTGTTGTTGCTGATTTACTGTTGTAA AAGACGCTACCAACAGACACTCAAGCAGCATACTAAGGTCGATCCGGCATTTAAACCTGATCTAACTGGA ACTTCGAAATCCTATGTGAGATCACTCTG
Protein Sequence	>NP_047205.1 fusion protein F [Canine morbillivirus] MHKGIPKSSKTQTHTQQDRPPQPSTELEETRTSRARHSTTSAQRSTHYDPRTSDRPVSYTMNRTRSRKQT SHRLKNIPVHGNHEATIQHIPESVSKGARSQIERRQPNAINSGSQCTWLVLWCLGMASLFLCSKAQIHWN NLSTIGIIGTDSVHYKIMTRPSHQYLVIKLMPNVSLIENCTKAELGEYEKLLNSVLEPINQALTLMTKNV KPLQSLGSGRRQRRFAGVVLAGVALGVATAAQITAGIALHQSNLNAQAIQSLRTSLEQSNKAIEEIREAT QETVIAVQGVQDYVNNELVPAMQHMSCELVGQRLGLRLLRYYTELLSIFGPSLRDPISAEISIQALIYAL GGEIHKILEKLGYSGSDMIAILESRGIKTKITHVDLPGKFIILSISYPTLSEVKGVIVHRLEAVSYNIGS QEWYTTVPRYIATNGYLISNFDESSCVFVSESAICSQNSLYPMSPLLQQCIRGDTSSCARTLVSGTMGNK FILSKGNIVANCASILCKCYSTSTIINQSPDKLLTFIASDTCPLVEIDGATIQVGGRQYPDMVYEGKVAL GPAISLDRLDVGTNLGNALKKLDDAKVLIDSSNQILETVRRSSFNFGSLLSVPILSCTALALLLLIYCCK RRYQQTLKQHTKVDPAFKPDLTGTSKSYVRSL
Molecule Role	Protective antigen
Molecule Role Annotation	Study reports the engineering and the characterization of two replication-competent canine adenovirus type 2 (CAV2)-based vaccines expressing, respectively, the CDV hemagglutinin (HA) and fusion (F) antigens (CDVgp5). We first demonstrated that the intranasal vaccination with a mixture of both recombinant CAV2s provides an excellent level of protection in seronegative puppies, confirming the value of replication-competent adenovirus-based vectors for mucosal vaccination (Fischer et al., 2002).
Related Vaccines(s)	ALVAC- CDV-H/F , Canine distemper virus DNA vaccine encoding F and HA , NYVAC- CDV-H/F
References

CDVgp5