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ompW

Gene Name ompW
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae
NCBI Protein GI ASU14913
Other Database IDs CDD:328747
Taxonomy ID 715
Protein Name Outer membrane protein W
Protein pI 8.7
Protein Weight 21467.67
Protein Length 291
Protein Note Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; cl21487
Protein Sequence 
>ASU14913.1 Outer membrane protein W [Actinobacillus pleuropneumoniae]
MKKAVLAAVLGGALLADSAMAHQAGDVIFRAGAIGVIANSSSDYQTGADVNLDVNNNIQLGLTGTYMLSD
NLGLELLAATPFSHKITGKLGATDLGEVAKVKHLPPSLYLQYYFFDSNATVRPYVGAGLNYTRFFSAESL
KPQLVQNLRVKKHSVAPIANLGVDVKLTDNLSFNAAAWYTRIKTTADYDVPGLGHVSTPITLDPVVLFSG
ISYKF
Molecule Role Protective antigen
Molecule Role Annotation APJL_0126, HbpA and OmpW were further tested in the natural host (swine) by homologous and heterologous challenges., showing that these proteins could induce high titers of antibodies, but vaccination with each protein individually elicited low protective immunity against A. pleuropneumoniae.(Chen et al., 2012)
Related Vaccines(s) A. pleuropneumoniae OmpW vaccine
References