VIOLIN: Vaccine Investigation and Online Information Network

ompA
Gene Name	ompA
Sequence Strain (Species/Organism)	Actinobacillus pleuropneumoniae
NCBI Protein GI	ABV82725
Other Database IDs	ATCC:27088 CDD:332966 CDD:143586
Taxonomy ID	715
Protein Name	OmpA
Protein pI	5.45
Protein Weight	26230.02
Protein Length	286
Protein Note	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; cl28145
Protein Sequence	>ABV82725.1 OmpA [Actinobacillus pleuropneumoniae] MQIDFSKLKLQQQESEDSQWLPVSDLMSGLMILFLFIAVSFILNAKRVADNYQDNQEKIYQALQTEFSPK LKDWKAKIDKDTLTFIFTDPEVLFETGRSDLNAPFKKILDDFFPRYMKVVDNYKTSISEIRIEGHTSTEW DHKSSDDMAYFLNMQLSQDRTRSVLIYLYQLENIAQYRDWIKSNLSAVGLSSSKTIKNTQGIEDKEASKR VTFRIITNAEEQLRKLSEIK
Molecule Role	Protective antigen
Molecule Role Annotation	The splenic lymphocyte proliferation and the levels of IL-4, IL-6 and IL-12 of the inoculated mice were significantly increased, and the T- and B-cell populations were also elevated. Collectively, the candidate may efficiently induce the Th1- and Th2-type immune responses.(Hur et al., 2016)
Related Vaccines(s)	mixture of Salmonella strains delivering ApxIA, ApxIIA, ApxIIIA and OmpA of A. pleuropneumoniae
References