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galU

Gene Name galU
Sequence Strain (Species/Organism) Francisella tularensis subsp. tularensis SCHU S4
NCBI Gene ID 3191600
NCBI Protein GI 56707872
Locus Tag FTT_0757
Genbank Accession AJ749949
Protein Accession YP_169768
Taxonomy ID 177416
Gene Starting Position 776923
Gene Ending Position 777786
Gene Strand (Orientation) ?
Protein Name UTP--glucose-1-phosphate uridylyltransferase
Protein pI 7
Protein Weight 30262.51
Protein Length 287
Protein Note Similar to Q9K0G7 UTP--glucose-1-phosphate uridylyltransferase from Neisseria meningitidis (serogroup B) (289 aa). FASTA: opt: 1017 Z-score: 1291.1 E(): 5e-64 Smith-Waterman score: 1017; 57.439 identity in 289 aa overlap.
DNA Sequence
>gi|255961454:776923-777786 Francisella tularensis subsp. tularensis SCHU S4, complete genome
AATGAAAATAAGAAAAGCAGTTTTTCCTGTAGCTGGATGGGGCACTAGATTTTTACCAGCTACTAAATCA
TGTCCTAAAGAAATGCTAACAGTTGTTGATAAACCATTGATCCAATATGCTGTTGAAGAGGCTATAGAGG
CAGGCTGTAAAGAGATAATATTTGTTACTAGCTCAAATAAAAAATCCCTAGAAGATCATTTTGATAGAAA
CTTTGAATTAGAATATTCGCTAGAAAAAAAACAAAAATATGAATTGTTAGATTTAGTAAAAAATATAATT
CCTAAAGATGTAAGTTTTTTCTTTGTACGTCAGCCAGAGGCGCTAGGACTAGGGCATGCGGTTTTATGTG
CAAAACCACTAGTTGGAATTGAGGATTTTGCAGTTATATTACCTGATGATTTAATTTACAATCATGATTG
TGGTACTGGTACGCTAAAGCAAATGGTTAAGGCGGTAGAAGGTACTGATATTAGAGGTTGTATCGCAACT
CAACAAGTCAAGAGAGAAAAAACAAATTCATATGGTATAGTTGCAAAAGATAATGATAATCTAATCAAAG
CAATTGTTGAAAAGCCAGCACCAGAAAAAGCACCATCAACTAATGCAGTTGTGGGTAGATATTTATTACC
AAATAAGATTTTTAGATGTTTAGAATCAACTTCAGAGGGCGCAGGTGGTGAGATTCAACTAACTGATGCT
ATCGCTAAATTATTAGATCAGGATGAGAAAATTTTGTCTTATGAATTTAAGGGTACTCGTTATGATTGTG
GCAGTAAATTAGGTTTTTTAATTGCTAATTATGAGATAGCTTTACAGCATCAAGAGTTAGGACATAAATT
CAAAGAATACCTTCAAAATAGATA
Protein Sequence
>gi|56707872|ref|YP_169768.1| UTP--glucose-1-phosphate uridylyltransferase [Francisella tularensis subsp. tularensis SCHU S4]
MKIRKAVFPVAGWGTRFLPATKSCPKEMLTVVDKPLIQYAVEEAIEAGCKEIIFVTSSNKKSLEDHFDRN
FELEYSLEKKQKYELLDLVKNIIPKDVSFFFVRQPEALGLGHAVLCAKPLVGIEDFAVILPDDLIYNHDC
GTGTLKQMVKAVEGTDIRGCIATQQVKREKTNSYGIVAKDNDNLIKAIVEKPAPEKAPSTNAVVGRYLLP
NKIFRCLESTSEGAGGEIQLTDAIAKLLDQDEKILSYEFKGTRYDCGSKLGFLIANYEIALQHQELGHKF
KEYLQNR
Molecule Role Virmugen
Molecule Role Annotation A galU mutant is attenuated in mice, with only transient weight loss observed. Two months after inoculation, mice were challenge with wild type F. tularensis and were protected, once again only experiencing transient weight loss (Jayakar et al., 2011).
Related Vaccines(s) Francisella tularensis galU mutant vaccine
References