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rpoB

Gene Name rpoB
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1255679
NCBI Protein GI 16767407
Locus Tag STM4153
Genbank Accession AF170176
Protein Accession NP_463022
Taxonomy ID 700720
Gene Starting Position 4365907
Gene Ending Position 4369935
Gene Strand (Orientation) +
Protein Name DNA-directed RNA polymerase subunit beta
Protein pI 4.89
Protein Weight 139687.68
Protein Length 1342
Protein Note DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
DNA Sequence
>gi|16763390:4365907-4369935 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
TATGGTTTACTCCTATACCGAGAAAAAACGTATTCGTAAGGATTTTGGTAAACGTCCACAAGTTCTGGAT
GTACCTTATCTCCTTTCTATCCAGCTTGACTCGTTTCAGAAGTTTATCGAGCAAGATCCTGAAGGGCAGT
ACGGCCTGGAAGCAGCCTTCCGTTCCGTGTTCCCGATTCAGAGCTACAGCGGTAATTCCGAGCTGCAGTA
CGTCAGCTACCGCCTTGGCGAACCGGTGTTTGACGTTCAGGAATGTCAGATCCGTGGCGTGACCTATTCC
GCACCGCTGCGCGTAAAACTGCGTCTGGTGATCTACGAGCGCGAAGCGCCGGAAGGCACCGTAAAAGACA
TTAAAGAACAAGAAGTCTACATGGGCGAAATTCCGCTCATGACCGACAACGGTACCTTTGTTATCAACGG
TACTGAGCGTGTTATCGTTTCTCAGCTGCACCGTAGCCCTGGCGTCTTCTTTGACTCCGACAAAGGTAAA
ACCCACTCTTCGGGTAAAGTGCTGTATAACGCGCGCATCATTCCTTACCGTGGTTCCTGGCTGGACTTCG
AATTCGATCCGAAGGACAACCTGTTCGTACGTATCGACCGTCGCCGTAAACTACCTGCGACCATCATCCT
GCGTGCGCTGAACTACACCACTGAGCAGATCCTTGACCTGTTCTTTGAGAAAGTCGTCTTCGAAATTCGC
GACAACAAACTGCAGATGGAGCTGATTCCAGAACGTCTGCGTGGCGAAACCGCGTCGTTCGATATCGAAG
CTAACGGCAAAGTGTACGTTGAAAAAGGCCGTCGCATTACCGCGCGTCACATCCGTCAGCTGGAAAAAGA
CGATATCAAGCATATCGAAGTTCCGGTTGAGTACATCGCAGGTAAAGTCGTCTCTAAAGACTACGTTGAC
GAATCTACTGGCGAGCTGATCTGCGCGGCGAACATGGAGCTGAGCCTGGATCTGCTGGCTAAGCTGAGCC
AGTCCGGCCACAAGCGTATCGAAACGCTGTTTACCAACGATCTGGACCACGGCCCGTACATTTCTGAAAC
GGTACGCGTCGACCCAACTAACGATCGTCTGAGCGCGCTGGTAGAAATCTACCGCATGATGCGCCCTGGT
GAGCCGCCGACACGCGAAGCGGCTGAAAGCCTGTTTGAGAACCTGTTCTTCTCCGAAGACCGCTATGACC
TGTCTGCGGTGGGTCGTATGAAGTTCAACCGTTCTCTGCTGCGCGACGAAATCGAAGGTTCCGGTATCCT
GAGCAAAGACGACATCATTGATGTCATGAAGAAGCTCATCGATATCCGTAACGGTAAAGGCGAAGTGGAT
GATATCGACCACCTCGGCAACCGTCGTATCCGTTCCGTCGGCGAAATGGCGGAAAACCAGTTCCGCGTTG
GCCTGGTGCGTGTAGAGCGTGCGGTGAAAGAGCGTCTGTCTCTGGGCGATCTGGATACCCTGATGCCTCA
GGATATGATCAACGCCAAGCCGATTTCCGCCGCAGTGAAAGAGTTCTTTGGTTCCAGCCAGCTGTCTCAG
TTTATGGACCAGAACAACCCGCTGTCTGAGATTACGCACAAACGTCGTATCTCCGCACTCGGCCCAGGCG
GTCTGACCCGCGAACGCGCAGGCTTCGAAGTTCGAGACGTACACCCGACGCACTACGGTCGCGTATGTCC
TATCGAAACGCCGGAAGGTCCGAACATCGGTCTGATCAACTCCCTGTCCGTGTACGCACAGACTAACGAA
TATGGCTTCCTTGAGACGCCGTACCGTCGTGTGGTTGATGGCGTGGTTACTGACGAAATTCATTACCTGT
CTGCTATCGAAGAAGGCAACTACGTTATCGCTCAGGCGAACTCCAACCTGGATGACGAAGGCCACTTTGT
AGAAGATTTGGTGACCTGCCGTAGCAAAGGCGAATCCAGCTTGTTCAGCCGCGACCAGGTTGACTACATG
GACGTTTCCACCCAGCAGGTGGTCTCCGTCGGTGCGTCCCTGATCCCGTTCCTGGAACACGATGACGCCA
ACCGTGCATTGATGGGTGCGAACATGCAACGTCAGGCGGTTCCGACTCTGCGCGCTGACAAGCCGCTGGT
GGGTACCGGTATGGAACGTGCTGTCGCCGTCGACTCCGGTGTTACTGCAGTAGCTAAACGTGGCGGTACT
GTTCAGTACGTGGATGCGTCCCGTATCGTTATCAAAGTTAACGAAGACGAGATGTACCCGGGCGAAGCGG
GTATCGACATCTATAACCTGACCAAATACACCCGCTCTAACCAGAACACCTGTATCAACCAGATGCCATG
TGTGTCTCTGGGCGAGCCGGTTGAACGCGGCGACGTGCTGGCAGACGGTCCGTCCACCGACCTCGGTGAA
CTGGCGCTCGGTCAGAACATGCGCGTGGCGTTCATGCCGTGGAACGGCTACAACTTCGAAGACTCCATTC
TCGTTTCCGAGCGTGTTGTCCAGGAAGACCGTTTCACCACCATCCACATTCAGGAACTGGCGTGCGTGTC
CCGTGACACCAAGCTGGGGCCGGAAGAGATCACCGCTGATATCCCGAACGTGGGTGAAGCTGCGCTCTCC
AAACTGGATGAATCCGGTATCGTTTACATCGGCGCGGAAGTGACAGGCGGTGACATTCTGGTCGGTAAGG
TGACGCCGAAAGGTGAAACCCAGCTGACGCCGGAAGAGAAACTGCTGCGTGCGATCTTCGGTGAGAAAGC
GTCTGACGTTAAAGACTCTTCTCTGCGCGTACCTAACGGTGTCTCCGGTACGGTTATCGACGTTCAGGTC
TTTACTCGCGATGGCGTAGAAAAAGACAAACGTGCTCTGGAAATCGAAGAGATGCAGCTCAAGCAGGCGA
AAAAAGACCTGTCTGAAGAACTGCAGATCCTCGAAGCGGGCCTGTTTAGCCGTATCCGTGCGGTGCTGGT
TTCCAGCGGCGTTGAAGCTGAGAAGCTCGACAAACTGCCGCGCGACCGCTGGCTGGAACTCGGTCTGACC
GACGAAGAGAAACAAAATCAGCTGGAACAACTGGCTGAGCAGTATGACGAACTGAAACACGAGTTCGAGA
AAAAACTTGAAGCGAAGCGCCGTAAAATCACCCAGGGCGACGATCTGGCGCCGGGCGTGCTGAAGATCGT
GAAGGTCTATCTGGCCGTTAAACGCCGTATCCAGCCGGGTGATAAGATGGCAGGTCGTCACGGTAACAAG
GGTGTTATCTCTAAGATCAACCCGATCGAAGACATGCCTTACGATGAAAACGGCACGCCGGTAGACATCG
TACTGAACCCGCTGGGCGTACCGTCTCGTATGAACATCGGCCAGATTCTGGAAACCCACCTGGGTATGGC
TGCGAAAGGTATTGGCGACAAGATTAACGCCATGCTGAAACAGCAGCAGGAAGTCGCGAAACTGCGCGAA
TTCATCCAGCGTGCCTACGATCTGGGCGCCGACGTTCGTCAGAAAGTCGACCTGAGCACCTTCAGCGATG
ATGAAGTGCTGCGTCTGGCAGAAAACCTGCGCAAAGGTATGCCGATTGCCACACCAGTGTTTGACGGTGC
GAAAGAAGCGGAAATCAAAGAGCTGCTGAAACTGGGCGACCTGCCGACCTCCGGTCAGATCACCCTGTTC
GATGGCCGTACGGGTGAACAGTTCGAACGTCCGGTAACCGTCGGTTACATGTACATGCTGAAACTGAACC
ACCTGGTTGATGACAAGATGCATGCGCGTTCTACCGGTTCTTACAGCCTGGTTACTCAGCAGCCGCTGGG
TGGTAAGGCGCAGTTCGGTGGTCAGCGCTTCGGGGAGATGGAAGTGTGGGCGCTGGAAGCTTACGGCGCC
GCCTACACCCTGCAGGAAATGCTCACCGTTAAGTCTGATGACGTGAATGGTCGTACCAAGATGTATAAGA
ACATCGTGGACGGCAACCATCAGATGGAACCGGGTATGCCGGAATCCTTCAACGTTCTGTTGAAAGAGAT
CCGCTCGCTGGGCATCAACATCGAACTGGAAGACGAGTA
Protein Sequence
>gi|16767407|ref|NP_463022.1| DNA-directed RNA polymerase subunit beta [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQY
VSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVING
TERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIIL
RALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKD
DIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISET
VRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGIL
SKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQ
DMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP
IETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLDDEGHFV
EDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLV
GTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPC
VSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVS
RDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA
SDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLV
SSGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIV
KVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA
AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGA
KEAEIKELLKLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLG
GKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEI
RSLGINIELEDE
Molecule Role Virmugen
Molecule Role Annotation A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs (Roesler et al., 2004).
Related Vaccines(s) Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine
References