• Vaccine Name: Pseudorabies recombinant vector vaccine encoding gp50 protein
• Target Pathogen: Pseudorabies virus
• Target Disease: Aujeszky's disease
• Vaccine Ontology ID: VO_0004003
• Type: Recombinant vector vaccine
• Status: Research
• gp50 gene engineering:
  • Type: Recombinant vector construction
  • Description:
  • Detailed Gene Information: Click Here.
• Immunization Route: Intramuscular injection (i.m.)

Pig Response

• Vaccination Protocol: 4-6 wk old male pigs from a PRV negative herd were vaccinated intramuscularly with two injections in the thigh of 10^7 CCID50 of NYVAC/gpSO 4 weeks apart. The control group was not vaccinated (Brockmeier and Mengeling, 1996).
• Challenge Protocol: Challenge consisted of administering 10^8 PFU of Indiana-Funkhauser strain of PRV oranasally, 4 weeks after the 2nd immunization (Brockmeier and Mengeling, 1996).
• Efficacy: Vaccinated pigs were protected from PRV challenge (Brockmeier and Mengeling, 1996).