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Vaccine Detail

Dendritic Cell Survivin Vaccine
Vaccine Information
  • Vaccine Name: Dendritic Cell Survivin Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: whole cell cancer vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Antigen: survivin+, CD11c+, Human Leukocyte Antigen - antigen D Related (HLA-DR)+ (NCT02851056)
  • Immunization Route: Intramuscular injection (i.m.)
  • Description: The Dendritic Cell Survivin Vaccine (DC:AdmS) is made using the participant's own blood cells. The vaccine will contain a virus called an adenovirus, similar the virus that causes the common cold. The dendritic cells contain survivin+, CD11c+, Human Leukocyte Antigen - antigen D Related (HLA-DR)+ by flow-cytometry. The vaccine is given in combination with G-CSF, T cells, and the CD34 progenitor cells. (NCT02851056)
Host Response
References
NCT02851056: Survivin Vaccine : Multiple Myeloma Autologous Hematopoietic Cell Transplant (HCT) [https://clinicaltrials.gov/study/NCT02851056]